KR20240034159A - 폴리펩티드 억제제 및 이의 용도 - Google Patents

폴리펩티드 억제제 및 이의 용도 Download PDF

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Publication number
KR20240034159A
KR20240034159A KR1020237036420A KR20237036420A KR20240034159A KR 20240034159 A KR20240034159 A KR 20240034159A KR 1020237036420 A KR1020237036420 A KR 1020237036420A KR 20237036420 A KR20237036420 A KR 20237036420A KR 20240034159 A KR20240034159 A KR 20240034159A
Authority
KR
South Korea
Prior art keywords
seq
amino acid
polypeptide
protein
fam19a5
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237036420A
Other languages
English (en)
Korean (ko)
Inventor
성재영
곽호윤
오시택
이민혁
정용우
하늬
조은호
이수현
이상명
이예림
조은비
이재근
김한별
권순구
Original Assignee
주식회사 뉴라클사이언스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 뉴라클사이언스 filed Critical 주식회사 뉴라클사이언스
Publication of KR20240034159A publication Critical patent/KR20240034159A/ko
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
KR1020237036420A 2021-07-08 2022-07-08 폴리펩티드 억제제 및 이의 용도 Pending KR20240034159A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163219670P 2021-07-08 2021-07-08
US63/219,670 2021-07-08
PCT/IB2022/056357 WO2023281475A1 (en) 2021-07-08 2022-07-08 Polypeptide inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
KR20240034159A true KR20240034159A (ko) 2024-03-13

Family

ID=84801485

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237036420A Pending KR20240034159A (ko) 2021-07-08 2022-07-08 폴리펩티드 억제제 및 이의 용도

Country Status (6)

Country Link
US (1) US20250333441A1 (https=)
EP (1) EP4367128A4 (https=)
JP (1) JP2024528351A (https=)
KR (1) KR20240034159A (https=)
CN (1) CN117881687A (https=)
WO (1) WO2023281475A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005508145A (ja) * 2001-06-15 2005-03-31 インサイト・ゲノミックス・インコーポレイテッド 細胞成長、分化および細胞死関連タンパク質
CN104254343A (zh) * 2012-02-15 2014-12-31 高丽大学校产学协力团 参与调节胶质细胞生成的fam19a5的医药用途
WO2019207513A1 (en) * 2018-04-24 2019-10-31 Neuracle Science Co., Ltd. Use of anti-family with sequence similarity 19, member a5 antibodies for the treatment of neuropathic pain
CN113195533B (zh) * 2019-01-02 2024-04-26 纽洛可科学有限公司 抗序列相似家族19成员a5的抗体及其使用方法

Also Published As

Publication number Publication date
EP4367128A1 (en) 2024-05-15
JP2024528351A (ja) 2024-07-30
CN117881687A (zh) 2024-04-12
WO2023281475A1 (en) 2023-01-12
EP4367128A4 (en) 2025-08-27
US20250333441A1 (en) 2025-10-30

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20231024

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)