JP2024528351A - ポリペプチド抑制剤及びその用途 - Google Patents

ポリペプチド抑制剤及びその用途 Download PDF

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Publication number
JP2024528351A
JP2024528351A JP2023522408A JP2023522408A JP2024528351A JP 2024528351 A JP2024528351 A JP 2024528351A JP 2023522408 A JP2023522408 A JP 2023522408A JP 2023522408 A JP2023522408 A JP 2023522408A JP 2024528351 A JP2024528351 A JP 2024528351A
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JP
Japan
Prior art keywords
seq
protein
amino acid
polypeptide
fam19a5
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Pending
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JP2023522408A
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English (en)
Japanese (ja)
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JP2024528351A5 (https=
Inventor
ヨン ソン，ジェ
クァク，ホユン
オ，シテク
イ，ミン－ヒョク
ジョン，ヨンウ
ハ，ヌイ
チョ，ウン－ホ
イ，スヒョン
イ，サン－ミョン
イ，イェリム
ビ チョ，ウン
クン イ，ジェ
キム，ハン－ビョル
クォン，スン－グ
Original Assignee
ニューラクル サイエンス カンパニー リミテッド
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Application filed by ニューラクル サイエンス カンパニー リミテッド filed Critical ニューラクル サイエンス カンパニー リミテッド
Publication of JP2024528351A publication Critical patent/JP2024528351A/ja
Publication of JP2024528351A5 publication Critical patent/JP2024528351A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
JP2023522408A 2021-07-08 2022-07-08 ポリペプチド抑制剤及びその用途 Pending JP2024528351A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163219670P 2021-07-08 2021-07-08
US63/219,670 2021-07-08
PCT/IB2022/056357 WO2023281475A1 (en) 2021-07-08 2022-07-08 Polypeptide inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2024528351A true JP2024528351A (ja) 2024-07-30
JP2024528351A5 JP2024528351A5 (https=) 2025-07-16

Family

ID=84801485

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023522408A Pending JP2024528351A (ja) 2021-07-08 2022-07-08 ポリペプチド抑制剤及びその用途

Country Status (6)

Country Link
US (1) US20250333441A1 (https=)
EP (1) EP4367128A4 (https=)
JP (1) JP2024528351A (https=)
KR (1) KR20240034159A (https=)
CN (1) CN117881687A (https=)
WO (1) WO2023281475A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005508145A (ja) * 2001-06-15 2005-03-31 インサイト・ゲノミックス・インコーポレイテッド 細胞成長、分化および細胞死関連タンパク質
CN104254343A (zh) * 2012-02-15 2014-12-31 高丽大学校产学协力团 参与调节胶质细胞生成的fam19a5的医药用途
WO2019207513A1 (en) * 2018-04-24 2019-10-31 Neuracle Science Co., Ltd. Use of anti-family with sequence similarity 19, member a5 antibodies for the treatment of neuropathic pain
CN113195533B (zh) * 2019-01-02 2024-04-26 纽洛可科学有限公司 抗序列相似家族19成员a5的抗体及其使用方法

Also Published As

Publication number Publication date
EP4367128A1 (en) 2024-05-15
KR20240034159A (ko) 2024-03-13
CN117881687A (zh) 2024-04-12
WO2023281475A1 (en) 2023-01-12
EP4367128A4 (en) 2025-08-27
US20250333441A1 (en) 2025-10-30

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