KR20240013778A - 신규한 아실화된 인슐린 유사체 - Google Patents
신규한 아실화된 인슐린 유사체 Download PDFInfo
- Publication number
- KR20240013778A KR20240013778A KR1020237044398A KR20237044398A KR20240013778A KR 20240013778 A KR20240013778 A KR 20240013778A KR 1020237044398 A KR1020237044398 A KR 1020237044398A KR 20237044398 A KR20237044398 A KR 20237044398A KR 20240013778 A KR20240013778 A KR 20240013778A
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- South Korea
- Prior art keywords
- cooh
- oeg
- human insulin
- insulin analogue
- desb30 human
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- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title claims abstract description 106
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Landscapes
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| CN202110570030.6 | 2021-05-24 | ||
| CN202110570030 | 2021-05-24 | ||
| PCT/CN2022/094392 WO2022247773A1 (en) | 2021-05-24 | 2022-05-23 | A novel acylated insulin analog |
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| WO2025098457A1 (zh) * | 2023-11-07 | 2025-05-15 | 甘李药业股份有限公司 | 用于降糖的酰化胰岛素 |
| WO2025098502A1 (zh) * | 2023-11-08 | 2025-05-15 | 甘李药业股份有限公司 | 包含胰岛素衍生物的药物组合物的治疗用途 |
| CN117756914B (zh) * | 2023-12-15 | 2024-09-03 | 瀚晖制药有限公司 | 依柯胰岛素的制备方法 |
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| WO2025228255A1 (zh) * | 2024-04-28 | 2025-11-06 | 正大天晴药业集团股份有限公司 | 酰化人胰岛素类似物 |
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2022
- 2022-05-23 CN CN202210567043.2A patent/CN115385843A/zh active Pending
- 2022-05-23 AU AU2022283328A patent/AU2022283328A1/en active Pending
- 2022-05-23 EP EP22810498.0A patent/EP4347632A4/en active Pending
- 2022-05-23 KR KR1020237044398A patent/KR20240013778A/ko active Pending
- 2022-05-23 US US18/563,090 patent/US20240374692A1/en active Pending
- 2022-05-23 CA CA3217734A patent/CA3217734A1/en active Pending
- 2022-05-23 WO PCT/CN2022/094392 patent/WO2022247773A1/en not_active Ceased
- 2022-05-23 JP JP2023572618A patent/JP2024521757A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240374692A1 (en) | 2024-11-14 |
| WO2022247773A1 (en) | 2022-12-01 |
| EP4347632A4 (en) | 2025-03-26 |
| EP4347632A1 (en) | 2024-04-10 |
| JP2024521757A (ja) | 2024-06-04 |
| CA3217734A1 (en) | 2022-12-01 |
| AU2022283328A1 (en) | 2023-11-16 |
| CN115385843A (zh) | 2022-11-25 |
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