KR20240004737A - 피임 화합물 및 방법 - Google Patents
피임 화합물 및 방법 Download PDFInfo
- Publication number
- KR20240004737A KR20240004737A KR1020237041162A KR20237041162A KR20240004737A KR 20240004737 A KR20240004737 A KR 20240004737A KR 1020237041162 A KR1020237041162 A KR 1020237041162A KR 20237041162 A KR20237041162 A KR 20237041162A KR 20240004737 A KR20240004737 A KR 20240004737A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- alkyl
- pharmaceutically acceptable
- acceptable salt
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 229940002612 prodrug Drugs 0.000 claims abstract description 10
- 239000012453 solvate Substances 0.000 claims abstract description 10
- -1 nitro, carboxy Chemical group 0.000 claims description 54
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- 125000003118 aryl group Chemical group 0.000 claims description 39
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 23
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163184014P | 2021-05-04 | 2021-05-04 | |
| US63/184,014 | 2021-05-04 | ||
| US202263307943P | 2022-02-08 | 2022-02-08 | |
| US63/307,943 | 2022-02-08 | ||
| US202263326524P | 2022-04-01 | 2022-04-01 | |
| US63/326,524 | 2022-04-01 | ||
| PCT/US2022/027506 WO2022235693A1 (en) | 2021-05-04 | 2022-05-03 | Contraceptive compounds and methods |
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|---|---|
| KR20240004737A true KR20240004737A (ko) | 2024-01-11 |
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| AU (1) | AU2022270088A1 (https=) |
| CA (1) | CA3217096A1 (https=) |
| IL (1) | IL308171A (https=) |
| MX (1) | MX2023012958A (https=) |
| WO (1) | WO2022235693A1 (https=) |
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| WO2025251031A1 (en) * | 2024-05-30 | 2025-12-04 | Yourchoice Therapeutics, Inc. | Contraceptive compounds and dosing for the same |
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| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| CN1255396C (zh) * | 1996-03-18 | 2006-05-10 | 卫材株式会社 | 含有稠环的羧酸衍生物 |
| US7105566B2 (en) * | 2002-10-22 | 2006-09-12 | Allergan, Inc. | Methods of treatment during vascular procedures |
| AU2015365738B2 (en) * | 2014-12-19 | 2020-07-23 | Galderma Research & Development | Novel compounds, synthesis method thereof and use of same in medicine and in cosmetics |
| WO2017201200A1 (en) * | 2016-05-19 | 2017-11-23 | Orphagen Pharmaceuticals, Inc. | Therapeutic compositions containing rar-alpha antagonists |
| WO2019014468A1 (en) * | 2017-07-13 | 2019-01-17 | Io Therapeutics, Inc. | RECEPTOR SUBTYPE AND RETINOID COMPOUNDS AND SELECTIVE REXINOIDS OF A FUNCTION IN COMBINATION WITH IMMUNE MODULATORS FOR ANTICANCER IMMUNOTHERAPY |
| EP3709990A4 (en) * | 2017-11-17 | 2021-12-01 | The Regents of the University of California | MANIPULATION OF THE RETIC ACID SIGNAL PATH |
| JP7828661B2 (ja) * | 2021-05-04 | 2026-03-12 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 避妊薬の化合物及び方法 |
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| US20250276962A1 (en) | 2025-09-04 |
| US20220388993A1 (en) | 2022-12-08 |
| US12281105B2 (en) | 2025-04-22 |
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