KR20230148332A - 운반체 물질과의 접합을 위한 항원 전구체를 포함하는 반응성 탄수화물의 합성을 위한 방법 - Google Patents

운반체 물질과의 접합을 위한 항원 전구체를 포함하는 반응성 탄수화물의 합성을 위한 방법 Download PDF

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Publication number
KR20230148332A
KR20230148332A KR1020237027069A KR20237027069A KR20230148332A KR 20230148332 A KR20230148332 A KR 20230148332A KR 1020237027069 A KR1020237027069 A KR 1020237027069A KR 20237027069 A KR20237027069 A KR 20237027069A KR 20230148332 A KR20230148332 A KR 20230148332A
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formula
compound
reaction
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carried out
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English (en)
Korean (ko)
Inventor
쯔 치에 시아오
세르게 미그나니
세르게 모펫
람 비슈와카르마
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코라넥스 캐피탈
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
KR1020237027069A 2021-01-15 2022-01-14 운반체 물질과의 접합을 위한 항원 전구체를 포함하는 반응성 탄수화물의 합성을 위한 방법 Pending KR20230148332A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN202121001963 2021-01-15
IN202121001963 2021-01-15
PCT/CA2022/050054 WO2022150924A1 (en) 2021-01-15 2022-01-14 Process for the synthesis of reactive carbohydrates including antigen precursors for conjugation with a carrier material

Publications (1)

Publication Number Publication Date
KR20230148332A true KR20230148332A (ko) 2023-10-24

Family

ID=82446854

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237027069A Pending KR20230148332A (ko) 2021-01-15 2022-01-14 운반체 물질과의 접합을 위한 항원 전구체를 포함하는 반응성 탄수화물의 합성을 위한 방법

Country Status (9)

Country Link
US (1) US20240308991A1 (https=)
EP (1) EP4277914A4 (https=)
JP (1) JP2024504658A (https=)
KR (1) KR20230148332A (https=)
CN (1) CN116981678A (https=)
AU (1) AU2022207897A1 (https=)
CA (2) CA3244715A1 (https=)
IL (1) IL304459A (https=)
WO (1) WO2022150924A1 (https=)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1007541B1 (en) * 1997-08-28 2006-08-23 Biomira, Inc. Randomly generated glycopeptide combinatorial libraries
FR2967068A1 (fr) * 2010-11-09 2012-05-11 Univ Joseph Fourier Derives de 6-amino-desoxyglucosamine et leur utilisation comme agents antibacteriens
CA3061205A1 (en) * 2017-04-25 2018-11-01 Memorial Sloan Kettering Cancer Center Triterpene saponin analogues
WO2019178699A1 (en) * 2018-03-23 2019-09-26 Koranex Capital Precision glycoconjugates as therapeutic tools
CN115003330A (zh) * 2019-09-23 2022-09-02 科纳克斯资本 作为疫苗和诊断工具的新糖缀合物

Also Published As

Publication number Publication date
EP4277914A1 (en) 2023-11-22
IL304459A (en) 2023-09-01
CA3167086A1 (en) 2022-07-21
JP2024504658A (ja) 2024-02-01
AU2022207897A9 (en) 2024-05-23
US20240308991A1 (en) 2024-09-19
AU2022207897A1 (en) 2023-08-03
CA3167086C (en) 2025-12-02
CA3244715A1 (en) 2025-11-29
CN116981678A (zh) 2023-10-31
WO2022150924A1 (en) 2022-07-21
EP4277914A4 (en) 2025-03-05

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PA0105 International application

Patent event date: 20230809

Patent event code: PA01051R01D

Comment text: International Patent Application

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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20250109

Comment text: Request for Examination of Application