JP2024504658A - 担体材料とコンジュゲートさせるための抗原前駆体を含む反応性炭水化物の合成プロセス - Google Patents

担体材料とコンジュゲートさせるための抗原前駆体を含む反応性炭水化物の合成プロセス Download PDF

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JP2024504658A
JP2024504658A JP2023543005A JP2023543005A JP2024504658A JP 2024504658 A JP2024504658 A JP 2024504658A JP 2023543005 A JP2023543005 A JP 2023543005A JP 2023543005 A JP2023543005 A JP 2023543005A JP 2024504658 A JP2024504658 A JP 2024504658A
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formula
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JP2024504658A5 (https=
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チー シャオ、ツェ
ミニャニ、セルジュ
モフェット、セルジュ
ヴィシュワカルマ、ラム
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コラネックス・キャピタル
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
JP2023543005A 2021-01-15 2022-01-14 担体材料とコンジュゲートさせるための抗原前駆体を含む反応性炭水化物の合成プロセス Pending JP2024504658A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN202121001963 2021-01-15
IN202121001963 2021-01-15
PCT/CA2022/050054 WO2022150924A1 (en) 2021-01-15 2022-01-14 Process for the synthesis of reactive carbohydrates including antigen precursors for conjugation with a carrier material

Publications (2)

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JP2024504658A true JP2024504658A (ja) 2024-02-01
JP2024504658A5 JP2024504658A5 (https=) 2025-01-10

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ID=82446854

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JP2023543005A Pending JP2024504658A (ja) 2021-01-15 2022-01-14 担体材料とコンジュゲートさせるための抗原前駆体を含む反応性炭水化物の合成プロセス

Country Status (9)

Country Link
US (1) US20240308991A1 (https=)
EP (1) EP4277914A4 (https=)
JP (1) JP2024504658A (https=)
KR (1) KR20230148332A (https=)
CN (1) CN116981678A (https=)
AU (1) AU2022207897A1 (https=)
CA (2) CA3244715A1 (https=)
IL (1) IL304459A (https=)
WO (1) WO2022150924A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003525837A (ja) * 1997-08-28 2003-09-02 バイオミラ，インコーポレイテッド ランダムに発生されるグリコペプチドのコンビナトリアルライブラリー
WO2012062996A1 (fr) * 2010-11-09 2012-05-18 Universite Joseph Fourier Derives de 6-amino-6-desoxyglucosamine et leur utilisation comme agents antibacteriens
WO2018200645A1 (en) * 2017-04-25 2018-11-01 Adjuvance Technologies, Inc. Triterpene saponin analogues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019178699A1 (en) * 2018-03-23 2019-09-26 Koranex Capital Precision glycoconjugates as therapeutic tools
CN115003330A (zh) * 2019-09-23 2022-09-02 科纳克斯资本 作为疫苗和诊断工具的新糖缀合物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003525837A (ja) * 1997-08-28 2003-09-02 バイオミラ，インコーポレイテッド ランダムに発生されるグリコペプチドのコンビナトリアルライブラリー
WO2012062996A1 (fr) * 2010-11-09 2012-05-18 Universite Joseph Fourier Derives de 6-amino-6-desoxyglucosamine et leur utilisation comme agents antibacteriens
WO2018200645A1 (en) * 2017-04-25 2018-11-01 Adjuvance Technologies, Inc. Triterpene saponin analogues

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TETRAHEDRON, vol. 70, JPN6026004741, 2014, pages 7283 - 7305, ISSN: 0005793306 *

Also Published As

Publication number Publication date
EP4277914A1 (en) 2023-11-22
IL304459A (en) 2023-09-01
CA3167086A1 (en) 2022-07-21
AU2022207897A9 (en) 2024-05-23
US20240308991A1 (en) 2024-09-19
AU2022207897A1 (en) 2023-08-03
CA3167086C (en) 2025-12-02
CA3244715A1 (en) 2025-11-29
CN116981678A (zh) 2023-10-31
KR20230148332A (ko) 2023-10-24
WO2022150924A1 (en) 2022-07-21
EP4277914A4 (en) 2025-03-05

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