KR20230134758A - Cosmetic composition for soothing or moisturizing skin containing oligopeptide nanocapsules - Google Patents

Abstract

The present invention provides a cosmetic composition expected to have skin soothing, skin moisturizing and skin barrier function improvement effects, including nanoencapsulated peptides, centella extract, calamine, hyaluronic acid, licorice extract, green tea extract, cypress extract and glycerin, It relates to skin barrier function improvement cosmetic and quasi-drug compositions containing this as an active ingredient, which has the effect of increasing skin moisture retention, resulting in a skin moisturizing effect, and thereby improving the skin barrier function. In addition, by nano-encapsulating the peptide and including it in the composition, it effectively prevents the peptide ingredient from deteriorating and being contaminated during storage/distribution, allowing it to penetrate the skin in its intact state when applied/applied to the skin. The effect of improving skin barrier function can be effectively achieved.

Description

Cosmetic composition for soothing or moisturizing skin containing oligopeptide nanocapsules {Cosmetic composition for soothing or moisturizing skin containing oligopeptide nanocapsules}

The present invention relates to a cosmetic composition for skin soothing or moisturizing containing oligopeptide nanocapsules.

The skin is an organ that comes in contact with the external environment. It protects the human body from physical damage or chemicals caused by external factors, prevents bacteria, mold, viruses, etc. from penetrating into the skin, and acts as a protective barrier to prevent moisture loss. . The skin consists of three layers: epidermis, dermis, and subcutaneous fat. Among these, the epidermis is the thinnest layer and performs an important function of moisturizing and protecting the skin. In particular, the skin has elasticity and softness due to the moisture present in the stratum corneum of the epidermis, and it is known that 10 to 20% moisture content is essential to maintain the elasticity of the stratum corneum.

Meanwhile, the stratum corneum, the outermost layer of the skin, contains lipid components such as free fatty acids, glycerolipids, and ceramides, and the natural moisturizing factor NMF (Natural Moisturizing Factor), a hydrophilic hygroscopic substance, plays an important role in maintaining skin flexibility and moisture. However, when the moisture content of the stratum corneum decreases (generally 10% or less), the skin becomes dry, itching, and atopic dermatitis may occur. Therefore, it is necessary to maintain moisture in the stratum corneum by providing a barrier that can suppress moisture loss even in a dry environment. There is a need to promote.

Today, moisturizer products used as cosmetic compositions to maintain moisture in the stratum corneum focus not only on simple moisture replenishment but also on restoring the skin barrier function, which is the most important function of the skin. In relation to this, products centered on natural moisturizing factors such as amino acids, sodium lactate, sodium pyrrolidone carboxylate, and urea, as well as high molecular compounds such as glycerin, hyaluronic acid, and polyethylene glycol, which have the property of retaining moisture well. products are being released, and today, the development of moisturizers focusing on peptide ingredients, the smallest unit with protein function, is also being actively developed.

The present invention is a cosmetic composition expected to have skin soothing, skin moisturizing, and skin barrier function improvement effects, including nanoencapsulated peptides, centella extract, calamine, hyaluronic acid, licorice extract, green tea extract, cypress extract, and glycerin. The purpose is to provide cosmetic and quasi-drug compositions that improve skin barrier function containing this as an active ingredient.

In addition, the technical problems to be solved by the present invention are not limited to the technical problems mentioned above, and other technical problems not mentioned will be clearly apparent to those skilled in the art from the description below. It will be understandable.

In the present specification, a cosmetic composition for soothing skin or moisturizing skin is provided including encapsulated peptide, centella extract, calamine, hyaluronic acid, licorice extract, green tea extract, cypress extract, and glycerin.

For example, the peptides include sh-Oligopeptide-5, rh-Oligopeptide-1, Copper Tripeptide-1, and Acetyl Tetrapeptide. -11 (Acetyl Tetrapeptide-11), Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Tripeptide-1, Acetyl Hexapeptide-8 It may be one or more selected from the group consisting of (Acetyl Hexapeptide-8), Hexapeptide-9, Palmitoyl Tetrapeptide-7, and Nonapeptide-1. .

For example, the peptide may be nanoencapsulated with one or more polymers selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methylcellulose, sodium carboxymethylcellulose, hydroxymethylpropylcellulose, and ethylcellulose.

For example, the nanoencapsulated peptide may be a sphere with a diameter of 100 to 200 nm.

For example, the Centella extract may be a fractionated extract obtained by fractionation with one or more fractionation solvents selected from the group consisting of butanol, acetone, hexane, ethanol, and water.

For example, the Centella extract contains Lactobacillus buchneri, Lactobacillus paracasei subsp. Tolerans, Lactobacillus harbinensis, and Saccharomyces in the fractionated extract. A fermented extract obtained by inoculating one or more strains selected from the group consisting of Saccharomycopsis fibuligera and Pichia kudriavzevii and naturally fermenting them for 24 to 36 hours under conditions of 28 to 33 ° C. It can be.

For example, the composition contains 20 to 50 parts by weight of centella extract, 10 to 30 parts by weight of calamine, 40 to 80 parts by weight of hyaluronic acid, 10 to 20 parts by weight of licorice extract, and 10 to 50 parts by weight of green tea extract per 100 parts by weight of the encapsulated peptide. It may contain 20 parts by weight, 5 to 15 parts by weight of Cypress extract, and 25 to 35 parts by weight of glycerin.

For example, the cosmetic composition includes preservatives, stabilizers, surfactants, thickeners, solubilizers, moisturizers, emollients, ultraviolet absorbers, preservatives, disinfectants, emulsifiers, antioxidants, pH adjusters, organic and inorganic pigments, fragrances, cooling agents, and It may further include at least one selected from limiting agents.

In addition, in this specification, the composition contains the above composition as an active ingredient, and is used in skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, sunscreen, We provide cosmetics that improve skin barrier function and have at least one formulation selected from foundation, essence, nutritional essence, pack, soap, shampoo, rinse, hair treatment, cleansing foam, cleansing lotion, cleansing cream, body lotion, and body cleanser. .

Additionally, the present specification provides a quasi-drug composition containing the composition as an active ingredient.

The skin soothing or skin moisturizing cosmetic composition according to the present invention, and the skin barrier function improving cosmetics and quasi-drugs containing the same as an active ingredient, increase skin moisture retention and bring about a skin moisturizing effect, thereby improving the skin barrier function. there is.

In addition, by nano-encapsulating the peptide and including it in the composition, it effectively prevents the peptide ingredient from deteriorating and being contaminated during storage/distribution, allowing it to penetrate the skin in its intact state when applied/applied to the skin. The effect of improving skin barrier function can be effectively achieved.

Figure 1 schematically shows steps for manufacturing a cosmetic composition according to an embodiment of the present invention.

Hereinafter, a cosmetic composition for skin soothing or skin moisturizing containing nanoencapsulated peptides, centella extract, calamine, hyaluronic acid, etc. according to specific embodiments of the present invention will be described in more detail.

As a term used throughout the claims and detailed description of this specification, 'skin barrier function' is an inherent function of the skin that protects the human body from physical damage and chemicals caused by external factors and prevents bacteria, fungi, and viruses from penetrating into the skin. It should be understood as a concept that includes the function of preventing moisture loss and maintaining elasticity by maintaining a sufficient amount of moisture.

The cosmetic composition according to one embodiment of the present invention has a skin soothing or skin moisturizing effect, and specifically contains encapsulated peptide, centella extract, calamine, hyaluronic acid, licorice extract, green tea extract, cypress extract, and glycerin. It may be.

In detail, a peptide is the smallest unit with protein function, a biological substance in which amino acids are linked through peptide bonds, and is a factor that plays an important role in our body. In particular, peptides are a combination of amino acids that make up the human body, so when used, they are quickly absorbed into the skin and rarely cause side effects.

For example, the peptides according to the present invention include sh-Oligopeptide-5, rh-Oligopeptide-1, Copper Tripeptide-1, Acetyl Tetrapeptide-11, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Tripeptide-1, Acetyl Hexapeptide One type selected from the group consisting of Acetyl Hexapeptide-8, Hexapeptide-9, Palmitoyl Tetrapeptide-7, and Nonapeptide-1 It may be more than one, and in detail, it may be SH-Oligopeptide-5 (sh-Oligopeptide-5) or RH-Oligopeptide-1 (rh-Oligopeptide-1).

On the other hand, peptides are substances in which amino acids are combined, and can lose their original secondary, tertiary, or quaternary structures due to external stimuli such as acids, bases, heat, inorganic salts, organic solvents, or radiation. There is a problem, and if it is denatured in this way, it may be difficult to fully perform its original role, such as maintaining moisture in the stratum corneum and improving skin barrier function, when applied to the skin. Therefore, in the present invention, peptides are nanoencapsulated and when applied to the skin, the nanocapsules are broken due to physical force and the peptides inside are released, so that the peptides react with other ingredients contained in the cosmetic composition until applied to the skin. It can effectively prevent peptides from being denatured.

Specifically, the nanoencapsulation method may be performed using a method commonly used in the art, and may be performed, for example, by a nano precipitation method.

Additionally, it may be nanoencapsulated with one or more polymers selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methylcellulose, sodium carboxymethylcellulose, hydroxymethylpropylcellulose, and ethylcellulose.

For example, the nanoencapsulated peptide may be a sphere with a diameter of 100 to 200 ㎚, and more specifically, it may be a sphere with a diameter of 80 to 150 ㎚.

Meanwhile, Centella asiatica, also called Centella asiatica, is a perennial herb that commonly grows in the mountains and fields of the southern islands of the Korean Peninsula. The main stem extends to the side and has two degenerated scale-shaped leaves near the node where the root comes from. Meanwhile, extracts of Centella are known to improve symptoms related to venous circulation disorders, such as lower extremity heaviness, pain, and restless lower extremity symptoms, and topical agents are known to be used for the auxiliary treatment of wounds and skin ulcers. Meanwhile, Centella extract is known to have triterpenoid saponins and flavonoids, including asiaticoside, as active ingredients.

Centella extract according to an embodiment of the present invention may be a solvent extract extracted with one or more solvents selected from water, ethanol, and methanol, and the extraction method includes hot water extraction and cold needle extraction commonly known in the art. , it may be performed by selecting one or more extraction methods selected from reflux cooling extraction, solvent extraction, steam distillation, ultrasonic extraction, elution, and compression methods.

Specifically, the Centella extract may be a fractionated extract obtained by fractionation with one or more fractionation solvents selected from the group consisting of butanol, acetone, hexane, ethanol, and water. Specifically, the Centella extract obtained by the above-described method may be It may be obtained by fractionating for 0.5 hours in a fractionation solvent mixed with 50% ethanol solution and butanol (BuOH) at a weight ratio of 1:1.

More specifically, the Centella extract contains Lactobacillus buchneri, Lactobacillus paracasei subsp. Tolerans, Lactobacillus harbinensis, and Saka in the fractionated extract. Obtained by natural fermentation for 24 to 36 hours under conditions of 28 to 33 ℃ by inoculating one or more strains selected from the group consisting of Saccharomycopsis fibuligera and Pichia kudriavzevii It may be a fermented extract.

On the other hand, when centella extract is fermented and used using the above strain, it can exhibit efficacy more suitable for skin soothing or skin moisturizing improvement purposes. Specifically, the strains may be cultured in YM medium or MRS medium at a temperature of 35°C for about 36 hours. Meanwhile, the strain may be inoculated at 0.5 to 1% by weight based on the total weight of Centella extract.

Meanwhile, the fermentation process may be performed for 24 to 36 hours under temperature conditions of 28 to 33°C after strain inoculation. Specifically, if fermented for less than 24 hours, there may be a problem that fermentation cannot be carried out effectively, and if fermented for more than 36 hours, contamination may be a problem.

On the other hand, the fermented product obtained by the above method may be obtained by additionally performing a process of separating the supernatant, filtering the supernatant, and sterilizing it, and then powdering it through hot air drying.

Meanwhile, calamine is a light red powder obtained by mixing zinc oxide and iron oxide, and is mainly used as a base for shaking lotions in cosmetics. Calamine lotion is suitable for people with weak skin because the zinc oxide as an ingredient has anti-inflammatory and protective effects. It is known to be used to treat acne-prone skin or skin after sunburn.

Meanwhile, hyaluronic acid is a complex polysaccharide made of amino acids and uronic acid, and is a high molecular compound made of N-acetylglucosamine and glucuronic acid. It is present in the vitreous body of the eye and the umbilical cord, and plays a role in preventing the invasion of bacteria or poisons. It is known to perform. Meanwhile, hyaluronic acid is a polymer compound with a molecular weight of about 200,000 to 400,000 in which N-acetylglucosamine and glucuronic acid are alternately bonded in a chain shape.

Meanwhile, the cosmetic composition for skin soothing or skin moisturizing according to an embodiment of the present invention contains 20 to 50 parts by weight of centella extract, 10 to 30 parts by weight of calamine, and 40 to 80 parts by weight of hyaluronic acid per 100 parts by weight of the encapsulated peptide. parts, 10 to 20 parts by weight of licorice extract, 10 to 20 parts by weight of green tea extract, 5 to 15 parts by weight of Cypress extract, and 25 to 35 parts by weight of glycerin.

The licorice extract, green tea extract, and cypress extract may be included to relieve skin irritation and have a skin soothing effect, and glycerin may be included to obtain an additional skin moisturizing effect.

Meanwhile, the cosmetic composition of the present invention may additionally contain ingredients commonly used in cosmetic compositions in addition to the above composition, such as preservatives, stabilizers, surfactants, thickeners, solubilizers, moisturizers, emollients, ultraviolet absorbers, and preservatives. , it may further include at least one selected from a disinfectant, an emulsifier, an antioxidant, a pH adjuster, an organic and inorganic pigment, a fragrance, a coolant, and an antiperspirant.

In addition, the cosmetic composition of the present invention can be prepared in any formulation commonly manufactured in the art, for example, solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, interface. It may be formulated as an activator-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, and spray, but is not limited thereto. More specifically, soft lotion, nourishing lotion, nourishing cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray, powder, hair tonic, hair cream, hair lotion, hair shampoo, hair. It can be manufactured in various forms such as rinse, hair conditioner, hair spray, hair aerosol, pomade, gel, etc., solution, brush gel, emulsion, oil, wax, aerosol, etc., but is not limited to this.

For example, the cosmetic composition may be a skin external preparation formulation intended to be used as a skin barrier function improving cosmetic or quasi-drug composition. When it has the skin external preparation formulation, it may be used as a softening lotion, nourishing lotion, essence, massage cream, nutritional cream, It may have a formulation of a pack, cleanser, gel, or skin-adhesive type cosmetic, and may also have a formulation of a transdermal administration type such as lotion, ointment, gel, cream patch, or spray.

In addition, in the external preparation composition of each dosage form, other ingredients in addition to the above essential ingredients can be appropriately selected and mixed by a person skilled in the art according to the dosage form or purpose of use of the external preparation without difficulty.

Specifically, when the formulation of the present invention is a paste, cream, or gel, the carrier ingredient may include animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, or zinc oxide. This can be used. When the formulation of the present invention is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder can be used as the carrier ingredient. In particular, when the formulation is a spray, chlorofluorohydrocarbon and propane may be used as carrier ingredients. /May contain propellants such as butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizing agent or emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol, or fatty acid ester of sorbitan can be used. When the formulation of the present invention is a suspension, the carrier ingredients include water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester, and polyoxyethylene sorbitan ester, and microcrystals. Cellulose, aluminum metahydroxide, bentonite, agar, or tracant may be used.

When the formulation of the present invention is a surfactant-containing cleansing agent, the carrier ingredients include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, and fatty acid amide. Ether sulfate, alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester can be used.

For example, the cosmetic composition includes skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, sunscreen, foundation, essence, nutritional essence, It may have at least one formulation selected from packs, soaps, shampoos, conditioners, hair treatments, cleansing foams, cleansing lotions, cleansing creams, body lotions, and body cleansers.

According to an embodiment of the present invention described above, a cosmetic composition for skin soothing or skin moisturizing, cosmetics and quasi-drugs containing the same as an active ingredient to improve skin barrier function, increase skin moisture retention, thereby bringing about a skin moisturizing effect, thereby improving skin barrier function. It has the effect of improving barrier function.

In addition, by nano-encapsulating the peptide and including it in the composition, it effectively prevents the peptide ingredient from deteriorating and being contaminated during storage/distribution, allowing it to penetrate the skin in its intact state when applied/applied to the skin. The effect of improving skin barrier function can be effectively achieved.

Hereinafter, the present invention will be described in detail through examples. The following examples are merely illustrative of the present invention, and the scope of the present invention is not limited to the following examples.

Example 1: Preparation of cosmetic composition

Prepared by mixing sh-Oligopeptide-5 (sh-Oligopeptide-5) and rh-Oligopeptide-1 (rh-Oligopeptide-1) in a 1:1 weight ratio and containing chitooligosaccharide, gelatin, pectin, and polyethylene glycol. After preparing the mixed solution, nano-encapsulated peptides in the form of spheres with a diameter of 80 to 150 nm were prepared through nano-precipitation.

Meanwhile, the Centella extract was obtained by extracting the washed Centella with 50% ethanol hot water, and fractionating the obtained ethanol hot water extract with a 50% ethanol solution and butanol (BuOH) in a fractionation solvent mixed at a weight ratio of 1:1 for 0.5 hours. A fractionated extract was obtained, and Lactobacillus harbinensis strain was inoculated at 1% by weight and naturally fermented for 24 to 36 hours under conditions of 28 to 33° C. to obtain a fermented extract.

Next, a cosmetic composition and a formulation containing the same were prepared as shown in Table 1 below.

ingredient Example 1 Nanoencapsulated peptides 10.0 centella extract 3.5 calamine 2.0 Hyaluronic acid 6.0 Licorice extract 1.5 green tea extract 1.5 Cypress extract 1.0 glycerin 3.0 Betaine 0.3 beta glucan 0.3 Hydrolyzed Collagen 0.3 galactomyces 0.3 olive oil 0.3 arginine 0.3 xanthan gum 1.5 carbomer 1.0 Purified water 67.2 Total weight (%) 100 (wt%)

Comparative Examples 1, 2, 3 and 4

A cosmetic composition was prepared in the same manner as in Example 1, except that the Centella extract was fractionated but not fermented (Comparative Example 1), and the Centella extract was not fractionated and only fermented (Comparative Example 2). The only difference was that the Centella extract itself was used (Comparative Example 3) and the peptide was not nanoencapsulated (Comparative Example 4).

[Experiment 1. Measurement of skin moisturizing effect]

The electrical conductivity of the skin surface was measured using a Corneometer (Courage + Khazaka, GmbH, Germany), and the test materials prepared in the examples and comparative examples described above were measured in a constant temperature and humidity room maintained at 23°C and 50% relative humidity. A certain amount was applied to the upper forearms of 30 healthy women (0.05/cm ² ), and the skin moisture content was measured immediately after application, 1 hour after application, and 2 hours after application, and normal skin without any treatment was used as a control group. The experimental results are shown in Table 2 below.

Immediately after application
skin electrical conductivity 1 hour after application
skin electrical conductivity 2 hours after application
skin electrical conductivity Example 1 83.4 82.5 80.3 Comparative Example 1 78.3 75.1 74.2 Comparative Example 2 76.7 74.6 73.1 Comparative Example 3 74.4 72.0 71.4 Comparative Example 4 65.4 63.2 62.5

Referring to the experimental results in Table 2, it was confirmed that the composition according to Example 1 of the present invention and the formulation containing the same provided superior skin moisture retention and sustainability compared to the comparative examples.

[Experiment 2. Sensory test to measure skin soothing effect]

Sensory evaluation of the cosmetic compositions of the above Examples and Comparative Examples was conducted, and the results are shown in Table 3 below. Sensory evaluation was conducted on 50 women using a formulation containing the cosmetic composition prepared according to Examples and Comparative Examples for 3 weeks, and then evaluated by applying a 5-point scale according to moisture, skin irritation, skin trouble, and preference. (5: very good, 4: excellent, 3: average, 2: poor, 1: very poor).

Moisturizing skin irritation Skin trouble preference Example 1 4.8 4.7 4.7 4.8 Comparative Example 1 4.3 4.4 4.5 4.3 Comparative Example 2 4.2 4.3 4.1 4.0 Comparative Example 3 4.2 4.1 4.1 4.0 Comparative Example 4 4.1 4.0 3.9 4.0

Referring to the results in Table 3, it was confirmed that the composition according to Example 1 of the present invention and the formulation containing the same had superior skin moisture retention ability, skin barrier function improvement ability, and consumer preference compared to the comparative examples.

Although specific embodiments of the present invention have been described and shown above, it is known in the art that the present invention is not limited to the described embodiments, and that various modifications and changes can be made without departing from the spirit and scope of the present invention. This is self-evident to those who have it. Accordingly, such modifications or variations should not be understood individually from the technical idea or viewpoint of the present invention, and the modified embodiments should be regarded as falling within the scope of the claims of the present invention.

Claims (10)

A cosmetic composition for soothing or moisturizing skin containing encapsulated peptides, centella extract, calamine, hyaluronic acid, licorice extract, green tea extract, cypress extract, and glycerin. According to claim 1,
The peptides include sh-Oligopeptide-5, rh-Oligopeptide-1, Copper Tripeptide-1, and Acetyl Tetrapeptide-11 ( Acetyl Tetrapeptide-11), Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Tripeptide-1, Acetyl Hexapeptide-8 -8), one or more types selected from the group consisting of Hexapeptide-9, Palmitoyl Tetrapeptide-7, and Nonapeptide-1, for skin soothing or skin Moisturizing cosmetic composition. According to claim 1,
The peptide is a skin soothing or skin care product nanoencapsulated with one or more polymers selected from the group consisting of chitooligosaccharide, gelatin, pectin, polyethylene glycol, methylcellulose, sodium carboxymethylcellulose, hydroxymethylpropylcellulose, and ethylcellulose. Moisturizing cosmetic composition. According to claim 3,
A cosmetic composition for skin soothing or skin moisturizing, wherein the nanoencapsulated peptide is a sphere having a diameter of 100 to 200 nm. According to claim 1,
The Centella extract is a cosmetic composition for skin soothing or skin moisturizing, which is a fractionated extract obtained by fractionating with one or more fractionation solvents selected from the group consisting of butanol, acetone, hexane, ethanol and water. According to claim 5,
The Centella extract contains Lactobacillus buchneri, Lactobacillus paracasei subsp. Tolerans, Lactobacillus harbinensis, and Saccharomycopsis blood in the fractionated extract. Skin, a fermented extract obtained by inoculating one or more strains selected from the group consisting of Saccharomycopsis fibuligera and Pichia kudriavzevii and naturally fermenting for 24 to 36 hours under conditions of 28 to 33 ° C. Cosmetic composition for soothing or moisturizing skin. According to claim 1,
The composition contains 20 to 50 parts by weight of centella extract, 10 to 30 parts by weight of calamine, 40 to 80 parts by weight of hyaluronic acid, 10 to 20 parts by weight of licorice extract, and 10 to 20 parts by weight of green tea extract per 100 parts by weight of the encapsulated peptide. , A cosmetic composition for skin soothing or skin moisturizing, comprising 5 to 15 parts by weight of cypress extract and 25 to 35 parts by weight of glycerin. According to claim 1,
The cosmetic composition includes preservatives, stabilizers, surfactants, thickeners, solubilizers, moisturizers, emollients, ultraviolet absorbers, preservatives, disinfectants, emulsifiers, antioxidants, pH adjusters, organic and inorganic pigments, fragrances, cooling agents and antiperspirants. A cosmetic composition for skin soothing or skin moisturizing, further comprising at least one selected ingredient. Contains the composition of claim 1 as an active ingredient,
Skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, sunscreen, foundation, essence, nutritional essence, pack, soap, shampoo, conditioner , Cosmetics that improve skin barrier function, having at least one formulation selected from hair treatment, cleansing foam, cleansing lotion, cleansing cream, body lotion, and body cleanser. A quasi-drug composition containing the composition of claim 1 as an active ingredient.