KR20230010593A - MARC1 유전자를 표적으로 하는 RNAi 제제 및 이의 용도 - Google Patents

MARC1 유전자를 표적으로 하는 RNAi 제제 및 이의 용도 Download PDF

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KR20230010593A
KR20230010593A KR1020220084498A KR20220084498A KR20230010593A KR 20230010593 A KR20230010593 A KR 20230010593A KR 1020220084498 A KR1020220084498 A KR 1020220084498A KR 20220084498 A KR20220084498 A KR 20220084498A KR 20230010593 A KR20230010593 A KR 20230010593A
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seq
marc1
rnai agent
antisense strand
group
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Korean (ko)
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홍선우
박준현
최정용
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올릭스 주식회사
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KR1020220084498A 2021-07-08 2022-07-08 MARC1 유전자를 표적으로 하는 RNAi 제제 및 이의 용도 Pending KR20230010593A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020210089864 2021-07-08
KR20210089864 2021-07-08

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KR20230010593A true KR20230010593A (ko) 2023-01-19

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KR1020220084498A Pending KR20230010593A (ko) 2021-07-08 2022-07-08 MARC1 유전자를 표적으로 하는 RNAi 제제 및 이의 용도

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US (1) US20250179498A1 (enExample)
EP (1) EP4368717A4 (enExample)
JP (2) JP7853399B2 (enExample)
KR (1) KR20230010593A (enExample)
CN (1) CN117677697A (enExample)
AU (1) AU2022308807B2 (enExample)
CA (1) CA3225054A1 (enExample)
WO (1) WO2023282704A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024186171A1 (ko) * 2023-03-08 2024-09-12 올릭스 주식회사 비만의 예방 또는 치료용 RNAi 제제 및 이를 이용한 병용 요법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR090905A1 (es) * 2012-05-02 2014-12-17 Merck Sharp & Dohme Conjugados que contienen tetragalnac y peptidos y procedimientos para la administracion de oligonucleotidos, composicion farmaceutica
TWI664187B (zh) * 2013-05-22 2019-07-01 阿尼拉製藥公司 絲胺酸蛋白酶抑制因子Ａ１ ｉＲＮＡ組成物及其使用方法
CN110799192A (zh) * 2017-03-27 2020-02-14 加利福尼亚大学董事会 治疗癌症的组合物和方法
US10835581B2 (en) * 2017-11-28 2020-11-17 University of Pittsburgh—of the Commonwealth System of Higher Education Method of treating insulin resistance
SG11202105900UA (en) * 2018-12-10 2021-07-29 Amgen Inc CHEMICALLY-MODIFIED RNAi CONSTRUCTS AND USES THEREOF
US20200241005A1 (en) * 2019-01-25 2020-07-30 Viscient Biosciences, Inc. Compositions and methods for the diagnosis and treatment of diseases of the liver
US12215382B2 (en) * 2019-03-01 2025-02-04 The General Hospital Corporation Liver protective MARC variants and uses thereof
WO2021237097A1 (en) * 2020-05-21 2021-11-25 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting marc1 gene expression
EP4196584A2 (en) * 2020-08-13 2023-06-21 Amgen Inc. Rnai constructs and methods for inhibiting marc1 expression
US11655473B2 (en) * 2021-05-28 2023-05-23 Novo Nordisk A/S Compositions and methods for inhibiting mitochondria amidoxime reducing component 1 (MARC1) expression

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024186171A1 (ko) * 2023-03-08 2024-09-12 올릭스 주식회사 비만의 예방 또는 치료용 RNAi 제제 및 이를 이용한 병용 요법

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Publication number Publication date
AU2022308807A1 (en) 2024-02-01
CN117677697A (zh) 2024-03-08
WO2023282704A1 (ko) 2023-01-12
JP2024525078A (ja) 2024-07-09
AU2022308807B2 (en) 2026-02-12
CA3225054A1 (en) 2023-02-12
EP4368717A1 (en) 2024-05-15
US20250179498A1 (en) 2025-06-05
JP7853399B2 (ja) 2026-04-28
JP2026120732A (ja) 2026-07-22
EP4368717A4 (en) 2026-07-01

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