KR20220146559A - 면역억제제를 포함하는 합성 나노담체를 사용하는 방법 및 조성물 - Google Patents

면역억제제를 포함하는 합성 나노담체를 사용하는 방법 및 조성물 Download PDF

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Publication number
KR20220146559A
KR20220146559A KR1020227033127A KR20227033127A KR20220146559A KR 20220146559 A KR20220146559 A KR 20220146559A KR 1020227033127 A KR1020227033127 A KR 1020227033127A KR 20227033127 A KR20227033127 A KR 20227033127A KR 20220146559 A KR20220146559 A KR 20220146559A
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South Korea
Prior art keywords
disease
immunosuppressant
subject
synthetic nanocarrier
disorder
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Pending
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KR1020227033127A
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English (en)
Korean (ko)
Inventor
페트르 일린스키
다카시 게이 기시모토
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셀렉타 바이오사이언시즈, 인크.
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Priority claimed from PCT/US2020/028132 external-priority patent/WO2021211100A1/en
Application filed by 셀렉타 바이오사이언시즈, 인크. filed Critical 셀렉타 바이오사이언시즈, 인크.
Publication of KR20220146559A publication Critical patent/KR20220146559A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
KR1020227033127A 2020-02-26 2021-02-26 면역억제제를 포함하는 합성 나노담체를 사용하는 방법 및 조성물 Pending KR20220146559A (ko)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US202062981606P 2020-02-26 2020-02-26
US202062981586P 2020-02-26 2020-02-26
US202062981594P 2020-02-26 2020-02-26
US202062981602P 2020-02-26 2020-02-26
US202062981595P 2020-02-26 2020-02-26
US202062981584P 2020-02-26 2020-02-26
US202062981589P 2020-02-26 2020-02-26
US202062981612P 2020-02-26 2020-02-26
US62/981,589 2020-02-26
US62/981,594 2020-02-26
US62/981,595 2020-02-26
US62/981,612 2020-02-26
US62/981,606 2020-02-26
US62/981,586 2020-02-26
US62/981,584 2020-02-26
US62/981,602 2020-02-26
PCT/US2020/028132 WO2021211100A1 (en) 2020-04-14 2020-04-14 Methods and compositions for inducing autophagy
USPCT/US2020/028132 2020-04-14
PCT/US2021/019927 WO2021174013A1 (en) 2020-02-26 2021-02-26 Methods and compositions using synthetic nanocarriers comprising immunosuppressant

Publications (1)

Publication Number Publication Date
KR20220146559A true KR20220146559A (ko) 2022-11-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227033127A Pending KR20220146559A (ko) 2020-02-26 2021-02-26 면역억제제를 포함하는 합성 나노담체를 사용하는 방법 및 조성물

Country Status (10)

Country Link
US (1) US20210290601A1 (https=)
EP (1) EP4110334A1 (https=)
JP (1) JP2023515202A (https=)
KR (1) KR20220146559A (https=)
CN (1) CN115379839A (https=)
AU (1) AU2021225955A1 (https=)
CA (1) CA3173734A1 (https=)
IL (1) IL295868A (https=)
MX (1) MX2022010568A (https=)
WO (1) WO2021174013A1 (https=)

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IL297274A (en) * 2020-04-14 2022-12-01 Selecta Biosciences Inc Methods and compositions for inducing autophagy
ES2986744A1 (es) * 2023-04-13 2024-11-12 Servicio Andaluz De Salud Rapamicina y estatinas como protectores frente daño hepático
CN117860782B (zh) * 2024-03-11 2024-05-28 中国康复科学所(中国残联残疾预防与控制研究中心) 双阴性t细胞在制备治疗脊髓损伤的药物中的用途

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Also Published As

Publication number Publication date
US20210290601A1 (en) 2021-09-23
AU2021225955A1 (en) 2022-09-22
CN115379839A (zh) 2022-11-22
CA3173734A1 (en) 2021-09-02
IL295868A (en) 2022-10-01
EP4110334A1 (en) 2023-01-04
MX2022010568A (es) 2022-11-30
JP2023515202A (ja) 2023-04-12
WO2021174013A1 (en) 2021-09-02

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