CA3173734A1 - Methods and compositions using synthetic nanocarriers comprising immunosuppressant - Google Patents

Methods and compositions using synthetic nanocarriers comprising immunosuppressant

Info

Publication number
CA3173734A1
CA3173734A1 CA3173734A CA3173734A CA3173734A1 CA 3173734 A1 CA3173734 A1 CA 3173734A1 CA 3173734 A CA3173734 A CA 3173734A CA 3173734 A CA3173734 A CA 3173734A CA 3173734 A1 CA3173734 A1 CA 3173734A1
Authority
CA
Canada
Prior art keywords
synthetic nanocarriers
immunosuppressant
subject
disease
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3173734A
Other languages
English (en)
French (fr)
Inventor
Petr Ilyinskii
Takashi Kei Kishimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cartesian Therapeutics Inc
Original Assignee
Selecta Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2020/028132 external-priority patent/WO2021211100A1/en
Application filed by Selecta Biosciences Inc filed Critical Selecta Biosciences Inc
Publication of CA3173734A1 publication Critical patent/CA3173734A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA3173734A 2020-02-26 2021-02-26 Methods and compositions using synthetic nanocarriers comprising immunosuppressant Pending CA3173734A1 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US202062981606P 2020-02-26 2020-02-26
US202062981586P 2020-02-26 2020-02-26
US202062981594P 2020-02-26 2020-02-26
US202062981602P 2020-02-26 2020-02-26
US202062981595P 2020-02-26 2020-02-26
US202062981584P 2020-02-26 2020-02-26
US202062981589P 2020-02-26 2020-02-26
US202062981612P 2020-02-26 2020-02-26
US62/981,589 2020-02-26
US62/981,594 2020-02-26
US62/981,595 2020-02-26
US62/981,612 2020-02-26
US62/981,606 2020-02-26
US62/981,586 2020-02-26
US62/981,584 2020-02-26
US62/981,602 2020-02-26
PCT/US2020/028132 WO2021211100A1 (en) 2020-04-14 2020-04-14 Methods and compositions for inducing autophagy
USPCT/US2020/028132 2020-04-14
PCT/US2021/019927 WO2021174013A1 (en) 2020-02-26 2021-02-26 Methods and compositions using synthetic nanocarriers comprising immunosuppressant

Publications (1)

Publication Number Publication Date
CA3173734A1 true CA3173734A1 (en) 2021-09-02

Family

ID=74947602

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3173734A Pending CA3173734A1 (en) 2020-02-26 2021-02-26 Methods and compositions using synthetic nanocarriers comprising immunosuppressant

Country Status (10)

Country Link
US (1) US20210290601A1 (https=)
EP (1) EP4110334A1 (https=)
JP (1) JP2023515202A (https=)
KR (1) KR20220146559A (https=)
CN (1) CN115379839A (https=)
AU (1) AU2021225955A1 (https=)
CA (1) CA3173734A1 (https=)
IL (1) IL295868A (https=)
MX (1) MX2022010568A (https=)
WO (1) WO2021174013A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX374963B (es) 2011-04-29 2025-03-06 Selecta Biosciences Inc Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos.
BR122020023215B1 (pt) 2013-05-03 2022-11-22 Selecta Biosciences, Inc Composição e kit de nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico
ES3036482T3 (en) 2017-03-11 2025-09-19 Cartesian Therapeutics Inc Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
AU2020287627A1 (en) 2019-06-04 2021-11-18 Selecta Biosciences, Inc. Formulations and doses of PEGylated uricase
IL297274A (en) * 2020-04-14 2022-12-01 Selecta Biosciences Inc Methods and compositions for inducing autophagy
ES2986744A1 (es) * 2023-04-13 2024-11-12 Servicio Andaluz De Salud Rapamicina y estatinas como protectores frente daño hepático
CN117860782B (zh) * 2024-03-11 2024-05-28 中国康复科学所(中国残联残疾预防与控制研究中心) 双阴性t细胞在制备治疗脊髓损伤的药物中的用途

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US4806621A (en) 1986-01-21 1989-02-21 Massachusetts Institute Of Technology Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
CA1340581C (en) 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
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US5843452A (en) * 1992-11-09 1998-12-01 Pharmagenesis, Inc. Immunotherapy composition and method
US5512600A (en) 1993-01-15 1996-04-30 Massachusetts Institute Of Technology Preparation of bonded fiber structures for cell implantation
US5514378A (en) 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
US5565215A (en) 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
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BR122020023215B1 (pt) * 2013-05-03 2022-11-22 Selecta Biosciences, Inc Composição e kit de nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico
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WO2023133319A1 (en) * 2022-01-10 2023-07-13 Selecta Biosciences, Inc. High affinity il-2 receptor agonists and synthetic nanocarrier dose sparing
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Also Published As

Publication number Publication date
US20210290601A1 (en) 2021-09-23
AU2021225955A1 (en) 2022-09-22
CN115379839A (zh) 2022-11-22
IL295868A (en) 2022-10-01
EP4110334A1 (en) 2023-01-04
KR20220146559A (ko) 2022-11-01
MX2022010568A (es) 2022-11-30
JP2023515202A (ja) 2023-04-12
WO2021174013A1 (en) 2021-09-02

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