KR20220123074A - 히드록시티로솔의 경구 생체 이용률 개선을 위한 폴리페놀계 조성물 및 용도 - Google Patents

히드록시티로솔의 경구 생체 이용률 개선을 위한 폴리페놀계 조성물 및 용도 Download PDF

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Publication number
KR20220123074A
KR20220123074A KR1020227026369A KR20227026369A KR20220123074A KR 20220123074 A KR20220123074 A KR 20220123074A KR 1020227026369 A KR1020227026369 A KR 1020227026369A KR 20227026369 A KR20227026369 A KR 20227026369A KR 20220123074 A KR20220123074 A KR 20220123074A
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KR
South Korea
Prior art keywords
hydroxytyrosol
composition
extract
polyphenol
use according
Prior art date
Application number
KR1020227026369A
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English (en)
Korean (ko)
Inventor
오스카 바누에로스 홀티구에라
루스 블란코 로조
조 안토니오 말도날도 로본
루이스 페레즈 마리네즈
호세 루이스 로페즈 라라멘디
모니카 마리아 올리바레즈 마틴
Original Assignee
바이오서치 에스.에이.
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Application filed by 바이오서치 에스.에이. filed Critical 바이오서치 에스.에이.
Publication of KR20220123074A publication Critical patent/KR20220123074A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/55—Linaceae (Flax family), e.g. Linum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
KR1020227026369A 2020-02-28 2021-02-26 히드록시티로솔의 경구 생체 이용률 개선을 위한 폴리페놀계 조성물 및 용도 KR20220123074A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESPCT/ES2020/070147 2020-02-28
ES2020070147 2020-02-28
PCT/EP2021/054840 WO2021170806A1 (en) 2020-02-28 2021-02-26 Uses and compositions based on polyphenols for improving the oral bioavailability of hydroxytyrosol

Publications (1)

Publication Number Publication Date
KR20220123074A true KR20220123074A (ko) 2022-09-05

Family

ID=70471066

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227026369A KR20220123074A (ko) 2020-02-28 2021-02-26 히드록시티로솔의 경구 생체 이용률 개선을 위한 폴리페놀계 조성물 및 용도

Country Status (10)

Country Link
EP (1) EP4110309A1 (zh)
JP (1) JP2023514680A (zh)
KR (1) KR20220123074A (zh)
CN (1) CN115003291A (zh)
AU (1) AU2021228197A1 (zh)
BR (1) BR112022015705A2 (zh)
CO (1) CO2022011987A2 (zh)
MX (1) MX2022010216A (zh)
TW (1) TWI795736B (zh)
WO (1) WO2021170806A1 (zh)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US5397894A (en) 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
US6258846B1 (en) 1999-06-01 2001-07-10 Drugtech Corporation Nutritional supplements
US7112609B2 (en) 1999-06-01 2006-09-26 Drugtech Corporation Nutritional supplements
ES2288123B1 (es) * 2006-06-05 2008-10-01 Furfural Español, S.A. Composicion alimentaria funcional rica en compuestos fenolicos y uso de dicha composicion.
WO2008006581A2 (en) * 2006-07-14 2008-01-17 Dsm Ip Assets B.V. Compositions and use thereof for the treatment, co-treatment or prevention of imflammatory disorders
MX2010000832A (es) * 2007-07-23 2010-07-06 Probelte Pharma S A Enriquecimiento de productos nutricionales con extractos de oliva conteniendo hidroxitirosol y productos nutricionales enriquecidos con hidroxitirosol.
FR2942224B1 (fr) * 2009-02-18 2012-11-30 Centre De Cooperation Internationale En Rech Agronomique Pour Le Developpement Cirad Procede d'extraction de composes phenoliques a partir d'eau de vegetation de l'olive et preparation d'extrait titre en polyphenols d'olive et de raisin
ES2592210T3 (es) * 2009-04-17 2016-11-28 Dsm Ip Assets B.V. Combinaciones de hidroxitirosol para mejorar la función mitocondrial y producción de energía
EP2338500A1 (en) * 2009-12-23 2011-06-29 Phenofarm S.r.l. Process for producing concentrated and refined actives from tissues and byproducts of Olea europaea with membrane technologies
EP3003338A1 (en) * 2013-05-29 2016-04-13 Nestec S.A. Compositions for use in cartilage breakdown
WO2015006651A1 (en) * 2013-07-11 2015-01-15 Specialty Nutrition Group, Inc. Compositions comprising hydroxytyrosol, resveratrol, lycopene, flavanols, and/or flavonoids and use thereof
RU2016107746A (ru) * 2013-08-09 2017-09-11 Сантори Холдингз Лимитед Средство, способствующее абсорбции гидрокситирозола и его производных in vivo, и применение такого средства

Also Published As

Publication number Publication date
TWI795736B (zh) 2023-03-11
CO2022011987A2 (es) 2022-09-09
AU2021228197A1 (en) 2022-07-07
WO2021170806A1 (en) 2021-09-02
EP4110309A1 (en) 2023-01-04
BR112022015705A2 (pt) 2022-09-27
JP2023514680A (ja) 2023-04-07
MX2022010216A (es) 2022-09-19
CN115003291A (zh) 2022-09-02
TW202131912A (zh) 2021-09-01

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