CO2022011987A2 - Usos y composiciones a base de polifenoles para mejorar la biodisponibilidad oral del hidroxitirol - Google Patents
Usos y composiciones a base de polifenoles para mejorar la biodisponibilidad oral del hidroxitirolInfo
- Publication number
- CO2022011987A2 CO2022011987A2 CONC2022/0011987A CO2022011987A CO2022011987A2 CO 2022011987 A2 CO2022011987 A2 CO 2022011987A2 CO 2022011987 A CO2022011987 A CO 2022011987A CO 2022011987 A2 CO2022011987 A2 CO 2022011987A2
- Authority
- CO
- Colombia
- Prior art keywords
- hydroxytyrosol
- polyphenols
- compositions
- hydroxytyrol
- improve
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
La invención se refiere a composiciones de origen natural, que comprenden hidroxitirosol y polifenoles que no son hidroxitirosol y que no se encuentran de forma natural en el olivo (O. europaea), caracterizadas por permitir una biodisponibilidad particularmente alta de hidroxitirosol y una actividad antiaterosclerótica particularmente alta de hidroxitirosol, una vez administrado por vía oral. Dichas composiciones pueden consistir en mezclas de extractos vegetales. La invención también se refiere al uso de dichas composiciones para el tratamiento de enfermedades cardiovasculares, en particular la aterosclerosis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES2020070147 | 2020-02-28 | ||
PCT/EP2021/054840 WO2021170806A1 (en) | 2020-02-28 | 2021-02-26 | Uses and compositions based on polyphenols for improving the oral bioavailability of hydroxytyrosol |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2022011987A2 true CO2022011987A2 (es) | 2022-09-09 |
Family
ID=70471066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2022/0011987A CO2022011987A2 (es) | 2020-02-28 | 2022-08-23 | Usos y composiciones a base de polifenoles para mejorar la biodisponibilidad oral del hidroxitirol |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP4110309A1 (es) |
JP (1) | JP2023514680A (es) |
KR (1) | KR20220123074A (es) |
CN (1) | CN115003291A (es) |
AU (1) | AU2021228197A1 (es) |
BR (1) | BR112022015705A2 (es) |
CO (1) | CO2022011987A2 (es) |
MX (1) | MX2022010216A (es) |
TW (1) | TWI795736B (es) |
WO (1) | WO2021170806A1 (es) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4540884A (en) | 1982-12-29 | 1985-09-10 | Finnigan Corporation | Method of mass analyzing a sample by use of a quadrupole ion trap |
US5397894A (en) | 1993-05-28 | 1995-03-14 | Varian Associates, Inc. | Method of high mass resolution scanning of an ion trap mass spectrometer |
US6258846B1 (en) | 1999-06-01 | 2001-07-10 | Drugtech Corporation | Nutritional supplements |
US7112609B2 (en) | 1999-06-01 | 2006-09-26 | Drugtech Corporation | Nutritional supplements |
ES2288123B1 (es) * | 2006-06-05 | 2008-10-01 | Furfural Español, S.A. | Composicion alimentaria funcional rica en compuestos fenolicos y uso de dicha composicion. |
WO2008006581A2 (en) * | 2006-07-14 | 2008-01-17 | Dsm Ip Assets B.V. | Compositions and use thereof for the treatment, co-treatment or prevention of imflammatory disorders |
MX2010000832A (es) * | 2007-07-23 | 2010-07-06 | Probelte Pharma S A | Enriquecimiento de productos nutricionales con extractos de oliva conteniendo hidroxitirosol y productos nutricionales enriquecidos con hidroxitirosol. |
FR2942224B1 (fr) * | 2009-02-18 | 2012-11-30 | Centre De Cooperation Internationale En Rech Agronomique Pour Le Developpement Cirad | Procede d'extraction de composes phenoliques a partir d'eau de vegetation de l'olive et preparation d'extrait titre en polyphenols d'olive et de raisin |
ES2592210T3 (es) * | 2009-04-17 | 2016-11-28 | Dsm Ip Assets B.V. | Combinaciones de hidroxitirosol para mejorar la función mitocondrial y producción de energía |
EP2338500A1 (en) * | 2009-12-23 | 2011-06-29 | Phenofarm S.r.l. | Process for producing concentrated and refined actives from tissues and byproducts of Olea europaea with membrane technologies |
EP3003338A1 (en) * | 2013-05-29 | 2016-04-13 | Nestec S.A. | Compositions for use in cartilage breakdown |
WO2015006651A1 (en) * | 2013-07-11 | 2015-01-15 | Specialty Nutrition Group, Inc. | Compositions comprising hydroxytyrosol, resveratrol, lycopene, flavanols, and/or flavonoids and use thereof |
RU2016107746A (ru) * | 2013-08-09 | 2017-09-11 | Сантори Холдингз Лимитед | Средство, способствующее абсорбции гидрокситирозола и его производных in vivo, и применение такого средства |
-
2021
- 2021-02-26 TW TW110107154A patent/TWI795736B/zh active
- 2021-02-26 CN CN202180010682.2A patent/CN115003291A/zh active Pending
- 2021-02-26 MX MX2022010216A patent/MX2022010216A/es unknown
- 2021-02-26 BR BR112022015705A patent/BR112022015705A2/pt unknown
- 2021-02-26 EP EP21708626.3A patent/EP4110309A1/en active Pending
- 2021-02-26 KR KR1020227026369A patent/KR20220123074A/ko unknown
- 2021-02-26 JP JP2022549378A patent/JP2023514680A/ja active Pending
- 2021-02-26 AU AU2021228197A patent/AU2021228197A1/en active Pending
- 2021-02-26 WO PCT/EP2021/054840 patent/WO2021170806A1/en unknown
-
2022
- 2022-08-23 CO CONC2022/0011987A patent/CO2022011987A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
TWI795736B (zh) | 2023-03-11 |
AU2021228197A1 (en) | 2022-07-07 |
WO2021170806A1 (en) | 2021-09-02 |
EP4110309A1 (en) | 2023-01-04 |
BR112022015705A2 (pt) | 2022-09-27 |
JP2023514680A (ja) | 2023-04-07 |
KR20220123074A (ko) | 2022-09-05 |
MX2022010216A (es) | 2022-09-19 |
CN115003291A (zh) | 2022-09-02 |
TW202131912A (zh) | 2021-09-01 |
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