KR20220122659A - 아우리스타틴-관련 화합물, 접합된 아우리스타틴 화합물, 및 이들의 사용 방법 - Google Patents

아우리스타틴-관련 화합물, 접합된 아우리스타틴 화합물, 및 이들의 사용 방법 Download PDF

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KR20220122659A
KR20220122659A KR1020227023304A KR20227023304A KR20220122659A KR 20220122659 A KR20220122659 A KR 20220122659A KR 1020227023304 A KR1020227023304 A KR 1020227023304A KR 20227023304 A KR20227023304 A KR 20227023304A KR 20220122659 A KR20220122659 A KR 20220122659A
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group
compound
val
target
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시브 슐라이어
브라이언 에이. 멘델손
피아 챌리타-이드
다우디 잭슨
크리스토퍼 켐볼
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싸이톰스 테라퓨틱스, 인크.
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    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020227023304A 2020-01-06 2021-01-06 아우리스타틴-관련 화합물, 접합된 아우리스타틴 화합물, 및 이들의 사용 방법 Ceased KR20220122659A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062957780P 2020-01-06 2020-01-06
US62/957,780 2020-01-06
PCT/US2021/012364 WO2021142029A1 (en) 2020-01-06 2021-01-06 Auristatin-related compounds, conjugated auristatin-related compounds, and methods of use thereof

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KR20220122659A true KR20220122659A (ko) 2022-09-02

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US (3) US20230071763A1 (https=)
EP (2) EP4087855A1 (https=)
JP (1) JP2023510724A (https=)
KR (1) KR20220122659A (https=)
CN (2) CN114929286A (https=)
AU (1) AU2021206218A1 (https=)
BR (1) BR112022013223A2 (https=)
CA (1) CA3163860A1 (https=)
CL (1) CL2022001773A1 (https=)
CO (1) CO2022010796A2 (https=)
EC (1) ECSP22061054A (https=)
IL (1) IL294456A (https=)
MX (1) MX2022008381A (https=)
PE (1) PE20221574A1 (https=)
PH (1) PH12022551426A1 (https=)
WO (3) WO2021142029A1 (https=)

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EP4087855A1 (en) * 2020-01-06 2022-11-16 CytomX Therapeutics, Inc. Auristatin-related compounds, conjugated auristatin-related compounds, and methods of use thereof
US20250333539A1 (en) 2022-03-23 2025-10-30 Cytomx Therapeutics, Inc. Activatable antigen-binding protein constructs and uses of the same
JP2025512798A (ja) 2022-03-25 2025-04-22 サイトムエックス セラピューティクス，インク． 活性化可能な二重アンカー型マスク化分子及びその使用方法
EP4504782A2 (en) 2022-04-01 2025-02-12 CytomX Therapeutics, Inc. Cd3-binding proteins and methods of use thereof
WO2023192973A1 (en) 2022-04-01 2023-10-05 Cytomx Therapeutics, Inc. Activatable multispecific molecules and methods of use thereof
JP2025525868A (ja) 2022-08-01 2025-08-07 サイトムエックス セラピューティクス，インク． プロテアーゼ切断性部分及びその使用方法
JP2025525867A (ja) 2022-08-01 2025-08-07 サイトムエックス セラピューティクス，インク． プロテアーゼ切断性部分及びその使用方法
AR130078A1 (es) 2022-08-01 2024-10-30 Cytomx Therapeutics Inc Substratos escindibles por proteasas, y métodos de uso de los mismos
EP4565250A1 (en) 2022-08-01 2025-06-11 CytomX Therapeutics, Inc. Protease-cleavable substrates and methods of use thereof
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