KR20220048988A - 대식세포 특이적 인게이저 조성물 및 이의 사용 방법 - Google Patents
대식세포 특이적 인게이저 조성물 및 이의 사용 방법 Download PDFInfo
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- KR20220048988A KR20220048988A KR1020227000747A KR20227000747A KR20220048988A KR 20220048988 A KR20220048988 A KR 20220048988A KR 1020227000747 A KR1020227000747 A KR 1020227000747A KR 20227000747 A KR20227000747 A KR 20227000747A KR 20220048988 A KR20220048988 A KR 20220048988A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962860055P | 2019-06-11 | 2019-06-11 | |
US62/860,055 | 2019-06-11 | ||
US201962908978P | 2019-10-01 | 2019-10-01 | |
US62/908,978 | 2019-10-01 | ||
PCT/US2020/037312 WO2020252208A2 (en) | 2019-06-11 | 2020-06-11 | Macrophage specific engager compositions and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20220048988A true KR20220048988A (ko) | 2022-04-20 |
Family
ID=73781864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020227000747A KR20220048988A (ko) | 2019-06-11 | 2020-06-11 | 대식세포 특이적 인게이저 조성물 및 이의 사용 방법 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20220241428A1 (pt) |
EP (1) | EP3983007A4 (pt) |
JP (1) | JP2022536684A (pt) |
KR (1) | KR20220048988A (pt) |
CN (1) | CN114340681A (pt) |
AU (1) | AU2020292339A1 (pt) |
BR (1) | BR112021024978A2 (pt) |
CA (1) | CA3140875A1 (pt) |
GB (1) | GB2603044A (pt) |
IL (1) | IL288788A (pt) |
MX (1) | MX2021015411A (pt) |
WO (1) | WO2020252208A2 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20170151281A1 (en) | 2015-02-19 | 2017-06-01 | Batu Biologics, Inc. | Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer |
CA3149897A1 (en) | 2019-09-03 | 2021-03-11 | Daniel Getts | Methods and compositions for genomic integration |
MX2023005201A (es) | 2020-11-04 | 2023-06-28 | Myeloid Therapeutics Inc | Composiciones de proteinas de fusion quimerica modificadas por ingenieria y metodos de uso de las mismas. |
EP4247419A1 (en) | 2020-11-18 | 2023-09-27 | Pionyr Immunotherapeutics, Inc. | Anti-marco antibodies and uses thereof |
WO2023039221A2 (en) * | 2021-09-10 | 2023-03-16 | Myeloid Therapeutics, Inc. | Macrophage specific engager compositions and methods of use thereof |
WO2023215814A2 (en) * | 2022-05-04 | 2023-11-09 | The Scripps Research Institute | Sialidase fusion molecules and related uses |
CN116059348A (zh) * | 2022-09-16 | 2023-05-05 | 四川大学华西医院 | 基于nkg2d的细胞接合器分子在清除衰老细胞中的应用 |
CN117205152B (zh) * | 2023-02-23 | 2024-04-09 | 南京大学 | 一种药物载体,其制备方法及其在疾病治疗中的应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
US6146850A (en) * | 1991-11-04 | 2000-11-14 | Xoma Corporation | Proteins encoding gelonin sequences |
WO1998005795A1 (en) * | 1996-08-02 | 1998-02-12 | The Center For Blood Research, Inc. | Enrichment of dendritic cells from blood |
US20090285757A1 (en) * | 2008-05-16 | 2009-11-19 | Northeastern University | Methods of targeting cells for diagnosis and therapy |
EP2332994A1 (en) * | 2009-12-09 | 2011-06-15 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Trispecific therapeutics against acute myeloid leukaemia |
SG11201705293WA (en) * | 2014-12-29 | 2017-07-28 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
CA3219372A1 (en) * | 2015-05-04 | 2016-11-10 | Affimed Gmbh | Combination of a cd30xcd16 antibody with a pd-1 antagonist for therapy |
WO2018140831A2 (en) * | 2017-01-27 | 2018-08-02 | Silverback Therapeutics, Inc. | Tumor targeting conjugates and methods of use thereof |
MX2019010172A (es) * | 2017-02-28 | 2019-12-18 | Affimed Gmbh | Combinacion de un anticuerpo anti-cd16a con una citocina. |
TW201900213A (zh) * | 2017-05-27 | 2019-01-01 | 美商免疫醫療公司 | 免疫球蛋白a陽性細胞的調節 |
CA3067244A1 (en) * | 2017-06-12 | 2018-12-20 | Emory University | T-cell antigen targeted chimeric antigen receptor (car) and uses in cell therapies |
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2020
- 2020-06-11 WO PCT/US2020/037312 patent/WO2020252208A2/en unknown
- 2020-06-11 KR KR1020227000747A patent/KR20220048988A/ko unknown
- 2020-06-11 US US17/618,349 patent/US20220241428A1/en active Pending
- 2020-06-11 JP JP2021573387A patent/JP2022536684A/ja active Pending
- 2020-06-11 CA CA3140875A patent/CA3140875A1/en active Pending
- 2020-06-11 EP EP20822720.7A patent/EP3983007A4/en active Pending
- 2020-06-11 BR BR112021024978A patent/BR112021024978A2/pt unknown
- 2020-06-11 CN CN202080057211.2A patent/CN114340681A/zh active Pending
- 2020-06-11 MX MX2021015411A patent/MX2021015411A/es unknown
- 2020-06-11 GB GB2118129.2A patent/GB2603044A/en active Pending
- 2020-06-11 AU AU2020292339A patent/AU2020292339A1/en active Pending
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2021
- 2021-12-08 IL IL288788A patent/IL288788A/en unknown
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GB2603044A (en) | 2022-07-27 |
AU2020292339A1 (en) | 2022-01-20 |
US20220241428A1 (en) | 2022-08-04 |
WO2020252208A3 (en) | 2021-01-21 |
EP3983007A2 (en) | 2022-04-20 |
BR112021024978A2 (pt) | 2022-05-10 |
MX2021015411A (es) | 2022-04-18 |
CA3140875A1 (en) | 2020-12-17 |
GB202118129D0 (en) | 2022-01-26 |
IL288788A (en) | 2022-02-01 |
CN114340681A (zh) | 2022-04-12 |
JP2022536684A (ja) | 2022-08-18 |
EP3983007A4 (en) | 2023-11-15 |
WO2020252208A2 (en) | 2020-12-17 |
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