KR20220008589A - Cosmetic Compostion For Moisturizing Skin Comprising Mixed Extracts of Cinnamomum loureirii Nees, Sanguisorba officinalis L. and Zingiber officinale As Active Ingredient - Google Patents

Abstract

The present invention relates to a cosmetic composition comprising a mixed extract of Cinnamomum loureirii Nees, Sanguisorba officinalis L., and Zingiber officinale as an active ingredient, and more specifically relates to a cosmetic composition for moisturizing skin which is excellent in a skin moisturizing effect and a skin barrier improvement effect.

Description

A cosmetic composition for moisturizing the skin comprising a mixed extract of cinnamon tree, cucumber grass and ginger as an active ingredient

The present invention relates to a cosmetic composition comprising a mixed extract of broiler broiler, cucumber grass and ginger as an active ingredient, and more particularly, to a cosmetic composition for moisturizing the skin.

The goal of cosmetics is to maintain beautiful and healthy skin, and to delay the aging of the skin that occurs naturally with aging. In general, aging is caused by oxidative damage to biomaterials by active oxygen, such as hydrogen peroxide, hydroxy radicals, and superoxide radicals. That is, reactive oxygen species peroxidize the lipids constituting the cell membrane to destroy the cell membrane, oxidize proteins, and attack hexane to cause oxidative damage, destroying biological materials and causing cell death. If this phenomenon continues, aging of the skin progresses, and wrinkles, loss of elasticity, and a crumbly appearance appear on the skin.

As we age, not only wrinkles and loss of elasticity, but also metabolic ability and blood circulation disorders occur, causing the skin to become rough and dark easily. The reason the skin becomes rough is because of a lack of moisture. In general, the moisture content of the skin consists of about 70% in the dermis layer and about 30%-10% in the epidermis layer. In the epidermal layer with keratinocytes, there are ingredients that have a hydrophilic structure called Natural Moisturizing Factor (NMF), which holds water molecules and maintains moisture. Natural moisturizing factors include sebum, amino acids, lactic acid, urea, and inorganic salts. These factors make the skin smooth and soft by maintaining about 30 to 10% of the moisture in the epidermal layer.

For this reason, it is very important to prevent skin aging to properly maintain the moisture content of the epidermal layer of the skin. However, natural moisturizing factors such as sodium pyrrolidone carboxylate (PCA-Na), sodium lactate, and urea, which are commonly used in cosmetics, can improve moisturizing power, but have strong electrolytic properties, so emulsification stability of cosmetics There is a problem that harms Amino acids, collagen, and elastin also have moisturizing properties, but there is a limit to their moisturizing ability. In addition, substances such as ascorbic acid, DL-α-tocopherol, and dibutyl hydroxyl toluene (BHT) have excellent antioxidant effects and prevent skin aging, thereby improving skin health. Maintains normal hydration. However, since these substances are used as synthetic products, they may cause skin stability problems when used for a long period of time or in large amounts. Therefore, it is one of the important research tasks in the cosmetic industry to develop substances that are safe, usable, and have a high moisturizing effect like natural moisturizing factors in external skin preparations.

Therefore, research on skin aging and moisture improvement is expected to continue, and many cosmetics using natural products are being developed to solve these skin problems and reduce skin irritation caused by various external factors. Natural ingredients have fewer side effects on the skin and are increasingly valuable as cosmetic raw materials as consumer response increases. To this end, research to develop substances with excellent safety and excellent skin-beauty effects by searching for the skin physiological activity of various natural materials is currently being actively conducted.

Various patent documents have been published on the moisturizing effect of plant extracts. Korean Patent No. 10-1814498 discloses a cosmetic composition containing a mixed extract of eucalyptus leaves and red shamrock leaves to have skin protection effects such as skin moisturizing enhancement and skin irritation relief. In addition, Korean Patent Registration No. 10-1926263 discloses a cosmetic composition containing marjoram, molochia and lemon balm mixed fermented extract to improve skin wrinkles, skin whitening, skin moisturizing, skin irritation relief and antioxidant effects.

Accordingly, the present inventors have studied the application potential of various natural materials, which are not known so far, to cosmetics. As a result, broiler trees, cucumber grass and ginger were selected and extracts were prepared therefrom to measure the moisturizing effect. As a result, the efficacy is very Because it is excellent, it was discovered that efficacy as a cosmetic can be expected.

It is an object of the present invention to provide a cosmetic composition for skin protection that contains a mixed extract of broiler broiler, cucumber grass and ginger to exhibit a moisturizing effect.

In addition, an object of the present invention is to provide a cosmetic composition that exhibits an efficacy effect by preparing a supercritical extract and an ultrasonic extract together with a solvent extract in order to maximize the efficacy of the mixed extract of broiler broiler, cucumber grass and ginger, and undergoing a purification process.

The above object is achieved by a cosmetic composition for moisturizing the skin containing a mixed extract of cinnamon, cucumber grass and ginger.

Preferably, the cosmetic composition has an effect of improving the skin barrier function.

Also preferably, the mixed extract of cinnamon tree, cucumber grass and ginger may be contained in an amount of 0.001 to 30.0% by weight based on the total weight of the cosmetic composition.

Also preferably, the broiler tree, cucumber grass and ginger mixed extract (a) purified water, methanol, ethanol, glycerin, ethyl acetate, butylene glycol, propylene glycol, dichloromethane, chloroform, ethyl ether, butylene glycol, hexane and It is characterized in that extraction is performed by an extraction method selected from the group consisting of a solvent extraction method for extraction using one or more solvents selected from the group consisting of mixtures thereof, (b) supercritical extraction method, and (c) ultrasonic extraction method.

Also preferably, the mixed extract is characterized in that it contains broiler broiler, cucumber grass and ginger in a mixed weight ratio of 1-3:1-3:1-3.

Also preferably, the cosmetic composition is a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing agent, oil, powder foundation, emulsion foundation, wax foundation and spray. It may have any one formulation selected from

The mixed extract of broiler tree, cucumber grass and ginger according to the present invention is excellent in moisturizing effect and skin barrier function recovery effect.

All technical terms used in the present invention, unless otherwise defined, have the following definitions and have the meanings as commonly understood by one of ordinary skill in the art of the present invention. In addition, although preferred methods and samples are described herein, similar or equivalent ones are also included in the scope of the present invention.

The term "about" means 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, means an amount, level, value, number, frequency, percentage, dimension, size, amount, weight or length varying by 4, 3, 2 or 1%.

Throughout this specification, unless the context requires otherwise, the terms "comprises" and "comprising" include, but are not limited to, a given step or element, or group of steps or elements, but any other step or element, or It is to be understood that a step or group of elements is not excluded.

The present invention relates to a cosmetic composition for moisturizing the skin containing a mixed extract of broiler broiler, cucumber grass and ginger.

Cinnamomum loureirii Nees is a tall evergreen tree reaching a height of 8 m. Leaves are alternate phyllotaxis, long oval, 10-12cm long. Flowers bloom in June, hang from the leaf axil of new branches in umbel, and have a light yellow-green color. The fruit is a berry, about 1.5cm long, and ripens black. Cinnamaldehyde, an active ingredient in broiler bark, is widely used for medicinal purposes and is known to have various pharmacological effects such as antipyretic, anti-inflammatory, and vascular relaxation.

Cucumber ( Sanguisorba officinalis L.) is a perennial herb belonging to the Rosaceae family. It grows in semi-shade or sunny grassy forests with good drainage and is 30-150 cm tall. The leaves are 2.5-5 cm long and 1-2.5 cm wide, with triangular saw teeth and oval shape. The root of cucumber plant is called jiyu (地楡) and is used as medicine. The root of cucumber plant contains Sanguisorbienin and tannin, which are known to be effective in hemostasis.

Ginger ( Zingiber officinale ) is a monocotyledonous perennial plant of the ginger family. The rhizome grows sideways, is fleshy, has a lumpy shape, and has a pungent taste and fragrant smell, so it is often used as a spice. In oriental medicine, dried rhizomes are used as medicine, and are known to be effective in treating chills, fever, headache, and phlegm caused by colds, and is also effective in stomach pain caused by eating and eating.

In the present invention, the broiler tree, cucumber grass and ginger mixed extract means obtained by extraction from various organs or parts of broiler tree, cucumber grass and ginger. Preferably, it can be extracted from the bark of a broiler tree, the root of cucumber grass and the rhizome of ginger.

In addition, the broiler tree, cucumber grass and ginger mixed extract can be prepared according to a conventional method known in the art. For example, extraction is performed using (a) solvent extraction, (b) supercritical extraction using reduced pressure and high temperature with carbon dioxide, or (c) ultrasonic extraction.

In the present invention, the mixed extract of broiler tree, cucumber grass and ginger is prepared using various extraction solvents, for example, water, anhydrous or hydrous lower alcohols having 1-4 carbon atoms (eg, methanol, ethanol, propanol and butanol), propylene glycol, It can be obtained using one or more extraction solvents selected from the group consisting of 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform, nucleic acids, and mixtures thereof, It is preferably obtained using ethanol, 70% (v/v) ethanol or water, and most preferably obtained using 70% (v/v) ethanol.

On the other hand, it will be apparent to those skilled in the art that, for the mixed extract of broiler tree, cucumber grass and ginger of the present invention, an extract exhibiting substantially the same effect can be obtained using other extraction solvents as well as the above-described extraction solvent.

In addition, the mixed extract of broiler broiler, cucumber grass and ginger of the present invention includes not only the extract using the above-described extraction solvent, but also an extract that has undergone a conventional purification and fermentation process. For example, decompression by carbon dioxide, extraction by supercritical extraction by high temperature, extraction by extraction using ultrasound, separation using an ultrafiltration membrane having a constant molecular weight cut-off value, various chromatography (size, charge, hydrophobicity or affinity Active fractions obtained through various purification and extraction methods that are separated by ) or additionally performed are also included in the extract of the present invention.

In addition, the present invention provides a cosmetic composition, characterized in that the extract is obtained by cooling the extract at room temperature, heating a liquid obtained by filtration, and further concentrating a solvent under reduced pressure or freeze-drying.

The extraction method by the supercritical extraction method by the reduced pressure by carbon dioxide and the high temperature refers to the supercritical fluid extraction method, and in general, the supercritical fluid is a liquid having a gas when it reaches a critical point under high temperature and high pressure conditions, and It has gaseous properties and chemically has a polarity similar to that of a non-polar solvent. Due to these properties, supercritical fluids are used for the extraction of fat-soluble substances (J. Chromatogr. A. 1998;479:200-205).

Carbon dioxide becomes a supercritical fluid with both liquid and gas properties as the pressure and temperature reach the critical point through the operation of the supercritical fluid device, and as a result, the solubility in fat-soluble solutes increases. When the supercritical carbon dioxide passes through an extraction vessel containing a certain amount of the sample, the fat-soluble substance contained in the sample is extracted into the supercritical carbon dioxide.

After extracting the fat-soluble substance, if supercritical carbon dioxide containing a small amount of co-solvent is again flowed through the sample remaining in the extraction container, components that were not extracted with pure supercritical carbon dioxide alone can be extracted.

The supercritical fluid used in the supercritical extraction method of the present invention can effectively extract the active ingredient by using supercritical carbon dioxide or a mixed fluid in which a cosolvent is additionally mixed with carbon dioxide.

As the co-solvent, one or a mixture of two or more selected from the group consisting of chloroform, olive oil, ethanol, methanol, water, ethyl acetate, nucleic acid and diethyl ether may be used. Preferably, one or a mixture of two or more selected from the group consisting of olive oil, ethanol, methanol, and water may be used.

Most of the extracted samples contain carbon dioxide, and since carbon dioxide is volatilized into the air at room temperature, the extract obtained by the above method can be used as a cosmetic composition, and the cosolvent can be removed by a vacuum evaporator.

In addition, the ultrasonic extraction method is an extraction method using energy generated by ultrasonic vibration, and ultrasonic waves can destroy an insoluble solvent contained in a sample in an aqueous solvent. Because the kinetic energy of the particles is increased, sufficient energy required for the reaction is obtained, and the high pressure is induced by the impact effect of ultrasonic energy to increase the mixing effect of the material and the solvent contained in the sample, thereby increasing the extraction efficiency.

The extraction solvent that can be used for the ultrasonic extraction method may be one or a mixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, nucleic acid, and diethyl ether. The extracted sample is vacuum filtered to recover the filtrate, then removed by a vacuum evaporator, and an extract can be obtained through a conventional extract preparation method of freeze-drying.

According to the present invention, the mixed extract of cinnamon tree, cucumber grass and ginger is contained in an amount of 0.001 to 30.0% by weight, preferably 0.01 to 20% by weight, more preferably 0.1 to 10% by weight, based on the total weight of the cosmetic composition. % is contained. When the content of the extract is less than 0.001% by weight, the skin moisturizing effect does not appear, and when it exceeds 30.0% by weight, the degree of increase in the skin moisturizing effect for the content increase is insignificant, there is a problem in safety and stability of the formulation, and economical not even an enemy

The mixed extract according to the present invention may include cinnamon tree, cucumber grass and ginger in a mixed weight ratio of 1 to 3:1 to 3:1 to 3, preferably in a mixed weight ratio of 1:1:1 .

After removing unnecessary ingredients through a purification process to use the broiler, cucumber grass and ginger mixed extract prepared by a conventional method in a cosmetic formulation, it may include a cosmetic composition exhibiting an efficacious effect. The purification process can be any conventional purification process, and liquid-liquid extraction using a difference in solubility, precipitation and a filter, and chromatography using the size of polarity and molecular weight, etc. can be used. Also, for example, after dissolving the mixed extract of broiler tree, cucumber grass and ginger in an aqueous ethanol solution (50% (v/v), 70% (v/v) solution, etc.) or other aqueous solution, the HP-20, sephadex column is filled After separating the water-soluble material and the oil-soluble material by using the difference in polarity and molecular weight using a column, the oil-soluble material is concentrated by TLC and freeze-dried to prepare a concentrate.

The ingredients included in the cosmetic composition of the present invention may include ingredients commonly used in cosmetic compositions in addition to the active ingredient as an active ingredient, for example, conventional ingredients such as antioxidants, stabilizers, solubilizers, vitamins, pigments and fragrances. adjuvants, and carriers.

The cosmetic composition of the present invention may be prepared in any formulation conventionally prepared in the art, for example, solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing , oil, powder foundation, emulsion foundation, wax foundation, pack, massage cream, spray, etc., but is not limited thereto. More specifically, it may be prepared in the form of a flexible lotion, a nourishing lotion, a nourishing cream, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray, or a powder.

When the formulation of the present invention is a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as a carrier component. can

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as a carrier component, for example, water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 ,3-butylglycol oil, glycerol fatty ester, polyethylene glycol or fatty acid ester of sorbitan.

When the formulation of the present invention is a suspension, as a carrier component, a liquid diluent such as water, ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, and microcrystals Adult cellulose, aluminum metahydroxide, bentonite, agar, or tracanth may be used.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In particular, in the case of a spray, additional chlorofluorohydrocarbon, propane /may contain propellants such as butane or dimethyl ether.

In the case of cleansing in which the formulation of the present invention contains a surfactant, aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, fatty acid as carrier components Amide ether sulfates, alkylamidobetaines, fatty alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters can be used.

When the cosmetic composition of the present invention is a soap, a surfactant-containing cleansing formulation, or a surfactant-free cleansing formulation, it may be applied to the skin and then wiped off, removed, or washed off with water. As a specific example, the soap is liquid soap, powder soap, solid soap, and oil soap, the surfactant-containing cleansing formulation is a cleansing foam, cleansing water, cleansing towel, and cleansing pack, and the surfactant-free cleansing formulation is a cleansing cream , cleansing lotion, cleansing water, and cleansing gel, but not limited thereto.

Hereinafter, the present invention will be described in more detail through a preparation example. These preparation examples are only for illustrating the present invention in more detail, and it will be apparent to those of ordinary skill in the art that the scope of the present invention is not limited by these preparation examples according to the gist of the present invention. .

Preparation Example 1 : Broiler tree, cucumber grass and ginger mixed extract

After washing the bark of the broiler tree, the root of cucumber, and the rhizome of ginger, it was rapidly cooled at -70°C, freeze-dried at -50°C and 5 m torr for 3 days, and then thoroughly pulverized using a grinder to prepare a powder. After mixing 60 g each of the prepared broiler bark, cucumber root, and ginger rhizome, it was extracted with 70% (v/v) ethanol solution under reflux 3 times for 5 hours each, cooled, and then cooled, Whatman # 4 Filtration with filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 6.7 g. Then, the dried broiler tree, cucumber grass and ginger mixed extract powder was used by dissolving it in 50% 1,3-butylene glycol.

Preparation Example 2 : Supercritical fluid mixed extract of broiler tree, cucumber grass and ginger

After mixing 60 g each of the prepared broiler bark, cucumber root, and ginger rhizome, it is used as a co-solvent in a supercritical state under a pressure of about 300 atmospheres (atm) at a temperature of about 60 ° C. Extracted using olive oil), salt was removed using an ultrafiltration membrane, and concentrated under reduced pressure and freeze-dried to obtain 31.3 g of a dried mixed extract powder of broiler, cucumber and ginger. This was used by dissolving it in 50% 1,3-butylene glycol.

Preparation Example 3 : Preparation of ultrasonic mixed extract of broiler, cucumber and ginger

After mixing 60 g each of the prepared broiler bark, cucumber root, and ginger rhizome, it was extracted using ultrasound (extracted at 30°C for about 2 hours at 25 KHz intensity using a Supernonic ultrasonic device). After removing the salt using an ultrafiltration membrane, 7.1 g was obtained through concentration under reduced pressure and freeze-drying. The prepared dried broiler tree, cucumber grass and ginger mixed extract powder was used by dissolving it in 50% 1,3-butylene glycol.

Preparation Example 4 : Broiler tree, cucumber grass and ginger mixed extract

After mixing 96 g, 48 g, and 48 g of the prepared broiler bark, cucumber root, and ginger rhizome, respectively, it was extracted with 70% (v/v) ethanol solution at reflux 3 times for 5 hours each, cooled, and cooled, after Whatman (Whatman) Filtered with #4 filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 6.7 g. Then, the dried broiler tree, cucumber grass and ginger mixed extract powder was used by dissolving it in 50% 1,3-butylene glycol.

Preparation Example 5 : Broiler tree, cucumber grass and ginger mixed extract

After mixing 48 g, 96 g, and 48 g of the prepared broiler bark, cucumber root, and ginger rhizome, respectively, it was extracted with 70% (v/v) ethanol solution under reflux 3 times for 5 hours, cooled, and cooled, (Whatman) Filtered with #4 filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 7.7 g. Then, the dried broiler tree, cucumber grass and ginger mixed extract powder was dissolved in 50% 1,3-butylene glycol and used.

Preparation Example 6 : Broiler tree, cucumber grass and ginger mixed extract

After mixing 48 g, 48 g, and 96 g of the prepared broiler bark, cucumber root, and ginger rhizome, respectively, it was extracted with 70% (v/v) ethanol solution under reflux 3 times for 5 hours each, cooled, and then cooled, Whatman (Whatman) Filtered with #4 filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 8.5 g. Then, the dried broiler tree, cucumber grass and ginger mixed extract powder was used by dissolving it in 50% 1,3-butylene glycol.

Comparative Preparation Example 1: Broiler Extract

192 g of the prepared broiler bark was extracted under reflux three times for 5 hours with 70% (v/v) aqueous ethanol solution, cooled, and filtered with Whatman #4 filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 10.7 g. Then, the dried broiler extract powder was used by dissolving it in 50% 1,3-butylene glycol.

Comparative Preparation Example 2 : Cucumber extract

192 g of the prepared root of cucumber plant was refluxed and extracted three times for 5 hours each with 70% (v/v) ethanol aqueous solution, cooled, and filtered with Whatman #4 filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 9.9 g. Then, the dried cucumber extract powder was used by dissolving it in 50% 1,3-butylene glycol.

Comparative Preparation Example 3 : Ginger Extract

192 g of the prepared rhizomes were extracted under reflux three times for 5 hours each with 70% (v/v) aqueous ethanol solution, cooled, and filtered with Whatman #4 filter paper. After removing salts from the filtered extract using an ultrafiltration membrane, it was concentrated under reduced pressure at 50° C. or less and freeze-dried to obtain 13.2 g. Then, the dried ginger extract powder was dissolved in 50% 1,3-butylene glycol and used.

Formulation example

Cosmetics (Formulation Examples 1 to 6) each comprising a broiler tree, cucumber grass and ginger mixed extract of Preparation Examples 1 to 6, and a cosmetic composition (Comparative Formulation Examples 3 to 5) comprising each of the broiler tree, cucumber grass, and ginger extracts It was prepared according to the composition of Table 1. In addition, for comparison of efficacy, a cosmetic composition containing glycerin and 1,3-butylene glycol as a moisturizer instead of a mixed extract of cinnamon tree, cucumber grass and ginger (Comparative Formulation Example 1), a cosmetic that does not contain either the extract or the moisturizer A composition (Comparative Formulation Example 2) was prepared according to the composition in Table 1 below.

Ingredients (wt%) Formulation Example 1 Formulation Example 2 Formulation Example 3 Formulation Example 4 Formulation Example 5 Formulation Example 6 Comparative Formulation Example 1 Comparative Formulation Example 2 Comparative Formulation Example 3 Comparative Formulation Example 4 Comparative Formulation Example 5 Preparation Example 1 5.0 - - - - - - - - - - Preparation 2 - 5.0 - - - - - - - - - Preparation 3 - - 5.0 - - - - - - - - Preparation 4 - - - 5.0 - - - - - - - Preparation 5 - - - - 5.0 - - - - - - Preparation 6 - - - - - 5.0 - - - - - Comparative Preparation Example 1 - - - - - - - - 5.0 - - Comparative Preparation Example 2 - - - - - - - - - 5.0 - Comparative Preparation Example 3 - - - - - - - - - - 5.0 glycerin - - - - - - 5.0 - - - - 1.3 Butylene Glycol - - - - - - 5.0 - - - - EDTA-2Na 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 cetostearyl alcohol 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Glyceryl Stearate 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 microcrystallin 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 squalane 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 liquid paraffin 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 trioctanoin 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 polysorbate 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Sorbitan Stearate 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 tocopheryl acetate 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 cyclomethicone 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 BHT 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 fragrance, preservative appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100

Experimental Example 1 : Skin electrical conductivity

The clinical moisturizing effect and lasting power of the cosmetic composition of the formulation were measured as follows. Through the survey, 150 healthy adult males and females who felt that their skin was dry were randomly formed into groups of 25, and Formulation Examples 1 to 6 and Comparative Formulation Examples 1 to 5 suitable for each group were administered twice a day for 4 weeks, respectively. was applied to both faces one by one. The moisturizing effect was evaluated by quantifying the increase rate (%) of skin electrical conductivity according to the amount of moisture in the epidermis using Corneometer CM 820 (Corage + Khazaka, Germany) for 2 weeks from the start of the actual use test and the improvement effect after the end. The experimental results are shown in Table 2 below.

division before use 2 weeks after use 4 weeks after use Formulation Example 1 30.76 45.31 58.22 Formulation Example 2 29.50 44.84 58.75 Formulation Example 3 30.20 47.35 61.35 Formulation Example 4 31.29 41.87 55.48 Formulation Example 5 30.16 42.25 54.44 Formulation Example 6 29.62 40.89 51.67 Comparative Formulation Example 1 30.75 39.33 49.00 Comparative Formulation Example 2 30.55 38.21 47.89 Comparative Formulation Example 3 28.98 40.12 50.25 Comparative Formulation Example 4 31.10 39.54 50.38 Comparative Formulation Example 5 29.85 39.87 50.45

As shown in Table 2, as a comparative formulation, the broiler of the present invention also compared to the cosmetics containing a chemical moisturizer (Comparative Formulation Examples 1 and 2) and the cosmetics containing the single extract (Comparative Formulation Examples 3 to 5), It was confirmed that the moisturizing effect of the cosmetics (Formulation Examples 1 to 6) containing the cucumber grass and ginger mixed extract was more excellent. In addition, when comparing Formulation Example 1 and Formulation Examples 4 to 6, it was confirmed that mixing at a mixing ratio of 1:1:1 is the most preferable since the efficacy of Formulation Example 1 is excellent.

Experimental Example 2: Skin barrier improvement effect

This study was conducted on 25 healthy women indoors at 25℃, 45% relative humidity, and no air flow. Skin barrier damage was induced by using a 1% aqueous solution of sodium lauryl sulfate (SLS), and after applying the cosmetic compositions of Formulation Examples 1 to 6 and Comparative Formulation Examples 1 and 2 to the upper arm, TEWAMETER TM210 (C+K eletronic GmhH. Germany) was used to measure the amount of transdermal water loss. That is, the skin barrier recovery rate (%) was confirmed by measuring the TEWL (Transepidermal Water Loss) value according to the change in TEWL value over time. The experimental results are shown in Table 3 below.

division Skin barrier recovery rate (%) 2D 4D 6D 8D Formulation Example 1 47.88 68.21 84.56 91.35 Formulation Example 2 48.46 65.66 83.32 90.21 Formulation Example 3 52.82 68.32 86.12 93.20 Formulation Example 4 45.55 62.21 68.85 85.56 Formulation Example 5 44.21 60.85 70.25 82.12 Formulation Example 6 46.33 60.10 69.32 77.95 Comparative Formulation Example 1 40.07 52.33 60.65 70.78 Comparative Formulation Example 2 35.65 47.62 57.75 65.22 Comparative Formulation Example 3 41.52 55.98 65.33 72.85 Comparative Formulation Example 4 43.21 57.53 63.21 70.12 Comparative Formulation Example 5 42.85 56.20 64.52 71.51

As shown in Table 3, Formulation Examples 1 to 6 containing the broiler tree, cucumber grass and ginger mixed extract were Comparative Formulation Examples 1 and 2 that did not contain the broiler tree, cucumber grass and ginger mixed extract, and Cosmetics containing the single extract It can be seen that the amount of transdermal water loss is improved compared to (Comparative Formulation Examples 3 to 5). In addition, when comparing Formulation Example 1 and Formulation Examples 4 to 6, it was confirmed that mixing at a mixing ratio of 1:1:1 is the most preferable since the efficacy of Formulation Example 1 is excellent.

Experimental Example 3: Safety Test

A human skin patch test was performed to determine whether the cosmetic compositions of Formulation Examples 1 to 6 were irritating to the skin. The test was conducted on 20 women in their 20s and 30s who had never had a hypersensitivity reaction to skin irritation in their past history and had no skin disease or skin allergy symptoms, and Comparative Formulation Examples 1 to 5 were used as control examples.

First, the test site was wiped with 70% ethanol and dried. The prepared test material was dropped into the Finn chamber (100X10, EPITEST) and then sealed and applied to the back of the test subject. The patch was applied for 24 hours, and 1 hour and 24 hours after the patch was removed, the presence or absence of erythema and edema at the test site was observed using a magnifying glass (8MC-150, DAZOR).

The skin reaction was determined according to the regulations (Table 4) of the International Contact Dermatitis Research Group (ICDRG), and the average skin reactivity was calculated according to Equation 1 below, and the results are shown in Table 5.

sign score Evaluation standard - 0 no response ± 0.5 faint or mild erythema + One Demarcated but mild erythema, edema and papules ++ 2 Distinct erythema, papules and vesicles +++ 3 Severe erythema and blistering, crusting

division 24 hours 48 hours Average skin reaction
(n=20) ± + ++ ± + ++ Formulation Example 1 One - - One - - 0.28 Formulation Example 2 - - - - - - 0.00 Formulation Example 3 One - - One - - 0.28 Formulation Example 4 One - - 2 - - 0.42 Formulation Example 5 2 - - 2 - - 0.42 Formulation Example 6 2 - - 2 - - 0.42 Comparative Formulation Example 1 2 - - 2 - - 0.42 Comparative Formulation Example 2 One - - One - - 0.28 Comparative Formulation Example 3 2 - - 2 - - 0.42 Comparative Formulation Example 4 One - - 2 - - 0.42 Comparative Formulation Example 5 One - - One - - 0.28

As shown in Table 5, the cosmetic compositions of Formulation Examples 1 to 6 did not cause skin irritation, so it was found that there was no abnormality in the safety of the cosmetic formulations containing the mixed extract of cinnamon, cucumber and ginger.

As described above in detail a specific part of the present invention, for those of ordinary skill in the art, this specific description is only a preferred embodiment, and it is clear that the scope of the present invention is not limited thereto. Accordingly, the substantial scope of the present invention will be defined by the appended claims and their equivalents.

Claims (5)

Cinnamon tree ( Cinnamomum loureirii Nees ), cucumber grass ( Sanguisorba officinalis L. ) and ginger ( Zingiber officinale ) A cosmetic composition for moisturizing the skin comprising a mixed extract as an active ingredient. The cosmetic composition for skin moisturizing according to claim 1, wherein the cosmetic composition has an effect of improving skin barrier function. The cosmetic composition for skin moisturizing according to claim 1, wherein the mixed extract is contained in an amount of 0.001 to 30.0% by weight based on the total weight of the cosmetic composition. The method according to claim 1, wherein the mixed extract of broiler broiler, cucumber grass and ginger is (a) water, anhydrous or hydrated lower alcohol having 1-4 carbon atoms, propylene glycol, butylene glycol, glycerin, acetone, ethyl acetate, chloroform, butyl A cosmetic composition for moisturizing the skin, which is extracted by a solvent extraction method using an extraction solvent selected from the group consisting of acetate, diethyl ether, dichloromethane, nucleic acids, and mixtures thereof, (b) supercritical extraction method, or (c) ultrasonic extraction method . The cosmetic composition for skin moisturizing according to claim 1, wherein the mixed extract contains broiler broiler, cucumber grass and ginger in a mixed weight ratio of 1-3:1-3:1-3.