KR20210143057A - Cleasing form composition having antimicrobial activity - Google Patents

Abstract

The present invention provides a cleansing foam composition containing, as active ingredients: hydroxyapatite; Aloe barbadensis leaf juice; a Centella asiatica extract; a Piper methysticum extract; a Viscum album extract; Prunus mume fruit filtrate fermented with Lactobacillus and Aspergillus; an Avena sativa powder extract; a Malpighia emarginata extract; a Vaccinium subg. Oxycoccus extract; a Vaccinium angustifolium extract; a Citrus sinensis extract; a Punica granatum extract; a Fragaria chiloensis extract; a Vitis vinifera extract; a Lonicera periclymenum extract; a Zanthoxylum piperitum fruit extract; a Pulsatilla vulgaris extract; a Citrus × paradisi extract; and a Carica papaya fruit extract.

Description

A cleansing foam composition with excellent antibacterial activity {CLEASING FORM COMPOSITION HAVING ANTIMICROBIAL ACTIVITY}

The present invention relates to a cleansing foam composition having excellent antibacterial activity, and more particularly, it is safe for the skin and removes various bacteria present on the skin through adsorption or sterilization process, but especially has excellent antibacterial activity against bacteria causing acne, At the same time, it relates to a cleansing foam composition that provides a whitening effect.

In general, cosmetics play a role in preventing moisture evaporation by forming a moisture barrier on the stratum corneum of the skin. When applying lipstick, powder, etc.) to the skin, it is strongly adsorbed to the skin and is not easily removed by ordinary soap or detergent in water. Therefore, to remove these cosmetics, first use a cleansing cream and then wash the rest of the cosmetic ingredients with water using a cleansing foam.

Cleansing Foam is a facial cleanser that removes facial waste and makeup residues with sufficient foam when removing makeup or general cleansing. The composition of a general cleansing foam contains a surfactant including fatty acid soap as the main component, and oil and moisturizer are blended for the purpose of excellent cleaning power. The alkali-type cleansing foam, which has fatty acid soap as its main ingredient, has excellent foaming properties, is easy to rinse, and is refreshing after use. In general, such cleansing foam cosmetics include a cream type, aerosol type (Korean Patent Publication No. 2003-0048255), and a solid type (Korea Patent Publication No. 1998-076171) cleansing foam containing a surfactant containing fatty acid soap as a main component.

Although the above various cleansing foams go through a rinsing process, they can only remove fine dust, bacteria, or viruses attached to the surface, but cannot fundamentally remove the bacteria that cause acne. Focusing on this point, they completed the present invention while researching a cleansing foam that provides antibacterial activity against acne bacteria at the same time as rinsing.

In order to solve the above problems, the present invention is safe for the skin and removes various bacteria present on the skin through adsorption or sterilization process, but has excellent antibacterial activity against bacteria causing acne, and at the same time provides a whitening effect is to do

The technical problem of the present invention as described above is achieved by the following means.

(1) Hydroxyapatite, Aloe vera leaf water, Centella asiatica extract, Kava kava extract, Mistletoe extract, Lactobacillus and Aspergillus plum fruit ferment filtrate, Oat flour extract, Acerola extract, Cranberry extract, Low sweet blueberry extract , Orange extract, pomegranate extract, beach strawberry extract, grape extract, honeysuckle extract, chrysanthemum fruit extract, walnut flower extract, grapefruit extract, and papaya fruit extract as active ingredients.

(2) in (1) above,

A cleansing foam composition comprising chamomile flower oil and tea tree leaf oil.

(3) in (2) above,

Decyl glucoside, sodium lauroyl glutamate, coco-glucoside, glycerin, sodium hyaluronate, potassium cocoate, sodium cocoyl ethionate, 1,2-hexanediol, stearic acid, lauric acid, potassium Hydroxide, myristic acid, betaine, butylene glycol, beta-glucan, allantoin, tocopherol, dimethyl sulfone and disodium EDIT A cleansing foam composition comprising more.

(4) in (1) above,

Hydroxyapatite 0.1 to 5% by weight, Aloe vera leaf water 20 to 30% by weight, Centella asiatica extract 0.1 to 5% by weight, Kava kava extract 0.1 to 5% by weight, Mistletoe extract 0.1 to 1% by weight, Lactobacillus and Aspergillus Plum tree fruit fermentation filtrate 0.1~1% by weight, oat flour extract 0.1~1% by weight, acerola extract 0.1~1% by weight, cranberry extract 0.1~1% by weight, low sweet blueberry extract 0.1~1% by weight, orange extract 0.1 to 1% by weight, pomegranate extract 0.1 to 1% by weight, beech strawberry extract 0.1 to 1% by weight, grape extract 0.1 to 1% by weight, honeysuckle extract 0.1 to 1% by weight, chrysanthemum extract 0.1 to 1% by weight , A cleansing foam composition containing 0.1 to 1% by weight of a wild flower extract, 0.1 to 1% by weight of a grapefruit extract, and 0.1 to 1% by weight of a papaya fruit extract as active ingredients.

(5) in (3) above,

Chamomile flower oil 0.1~1% by weight, tea tree leaf oil 0.1~1% by weight, decylglucoside 10~15% by weight, sodium lauroyl glutamate 5~15% by weight, coco-glucoside 5~10% by weight, glycerin 5~ 10% by weight, sodium hyaluronate 5-10% by weight, potassium cocoate 3-8% by weight, sodium cocoylethionate 2-6% by weight, 1,2-hexanediol 0.1-2% by weight, Stearic acid 1-5% by weight, lauric acid 1-5% by weight, potassium hydroxide 0.1-5% by weight, myristic acid 0.1-5% by weight, betaine 0.1-5% by weight, butylene glycol 0.1 ~5% by weight, beta-glucan 0.1~5% by weight, allantoin 0.1~1% by weight, tocopherol 0.1~1% by weight, dimethylsulfone 0.1~1% by weight and disodium EDTA 0.1~1% by weight. Cleansing foam composition, characterized in that.

The cleansing foam composition of the present invention is safe for the skin and removes various bacteria present on the skin through adsorption or sterilization process, but has excellent antibacterial activity against bacteria causing acne, and at the same time provides a whitening effect.

Hereinafter, the present invention will be described in more detail.

The cleansing foam composition according to the present invention comprises hydroxyapatite, aloe vera leaf water, centella asiatica extract, kava kava extract, mistletoe extract, lactobacillus and aspergillus plum tree fruit fermentation filtrate, oat powder extract, acerola extract, cranberry extract, Low-sweet blueberry extract, orange extract, pomegranate extract, beach strawberry extract, grape extract, honeysuckle extract, chrysanthemum fruit extract, walnut flower extract, grapefruit extract, and papaya fruit extract are contained as active ingredients.

The cleansing foam composition according to the present invention exhibits antibacterial activity through adsorption of bacteria, viruses or various fine dust by hydroxyapatite, and in addition to aloe vera leaf water, centella asiatica extract, kava kava extract, mistletoe extract, lactobacillus and Aspergillus plum tree fruit fermentation filtrate, oat powder extract, acerola extract, cranberry extract, lowsweet blueberry extract, orange extract, pomegranate extract, beach strawberry extract, grape extract, honeysuckle extract, It provides a cleansing foam composition having a very large synergistic effect in antibacterial activity and excellent whitening effect by adding a mixed extract consisting of an extract of Halmi flower extract, a grapefruit extract, and a papaya fruit extract.

In addition, the present invention preferably chamomile flower oil, tea tree leaf oil, decyl glucoside, sodium lauroyl glutamate, coco-glucoside, glycerin, sodium hyaluronate, potassium cocoate, sodium cocoyl ethionate, 1 ,2-hexanediol, stearic acid, lauric acid, potassium hydroxide, myristic acid, betaine, butylene glycol, beta-glucan, allantoin, tocopherol, dimethyl sulfone and disodium EDTA include more

Among the ingredients, chamomile flower oil and tea tree leaf oil are preferable in terms of not only improving the physical properties of the cleansing foam, but also retaining its own antibacterial activity and more sustaining the antibacterial power of the composition.

The composition according to the present invention comprises 0.1 to 5% by weight of hydroxyapatite, 20 to 30% by weight of aloe vera leaf water, 0.1 to 5% by weight of Centella asiatica extract, 0.1 to 5% by weight of kava kava extract, 0.1 to 1% by weight of mistletoe extract, Lactobacillus and Aspergillus fermented plum fruit filtrate 0.1~1% by weight, oat flour extract 0.1~1% by weight, acerola extract 0.1~1% by weight, cranberry extract 0.1~1% by weight, low-sweet blueberry extract 0.1 ~1% by weight, orange extract 0.1~1% by weight, pomegranate extract 0.1~1% by weight, beach strawberry extract 0.1~1% by weight, grape extract 0.1~1% by weight, honeysuckle extract 0.1~1% by weight, Chopi tree It contains 0.1 to 1% by weight of a fruit extract, 0.1 to 1% by weight of a wild flower extract, 0.1 to 1% by weight of a grapefruit extract, and 0.1 to 1% by weight of a papaya fruit extract as active ingredients.

In addition, the composition according to the present invention is preferably 0.1 to 1% by weight of chamomile flower oil, 0.1 to 1% by weight of tea tree leaf oil, 10 to 15% by weight of decyl glucoside, 5 to 15% by weight of sodium lauroyl glutamate, coco- Glucoside 5-10% by weight, glycerin 5-10% by weight, sodium hyaluronate 5-10% by weight, potassium cocoate 3-8% by weight, sodium cocoylethionate 2-6% by weight, 1,2 -Hexanediol 0.1-2 wt%, stearic acid 1-5 wt%, lauric acid 1-5 wt%, potassium hydroxide 0.1-5 wt%, myristic acid 0.1-5 wt%, betaine 0.1 ~5% by weight, butylene glycol 0.1-5% by weight, beta-glucan 0.1-5% by weight, allantoin 0.1-1% by weight, tocopherol 0.1-1% by weight, dimethylsulfone 0.1-1% by weight and disodium DTA further comprises 0.1 to 1% by weight.

The extract among the components may be prepared by hot water extraction or extraction with an organic solvent such as anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms and then concentration under reduced pressure. For the fermented plum tree fruit filtrate of Lactobacillus and Aspergillus, 1% by weight of mixed bacteria obtained by mixing Lactobacillus and Aspergillus oryzae in a ratio of 1:1 by weight was added to the juice of the plum tree fruit, and 10% at 30°C. Let it be obtained by filtering the fermented product obtained by time-fermenting.

The ingredients included in the cosmetic composition of the present invention include ingredients commonly used in cosmetic compositions in addition to the active ingredients, for example, conventional adjuvants such as antioxidants, stabilizers, solubilizers, vitamins, pigments and fragrances, and carriers. may include more.

Hereinafter, preferred examples are presented to help the understanding of the present invention, but the following examples are only illustrative of the present invention, and the scope of the present invention is not limited to the following examples.

[Example]

The cleansing foams of Examples 1,2 and Comparative Examples 1, 2 and 3 were prepared with the ingredients and contents shown in Table 1 below.

Manufacture of cleansing foam Composition (wt%) Example comparative example One 2 One 2 3 hydroxyapatite One One - - One Aloe Vera Leaf Water 25.78 25.78 25.78 25.78 - Centella asiatica extract One One One One - Kava Kava Extract (Leaf/Root/Stem) 1.2 1.2 1.2 1.2 - Mistletoe Extract 0.2 0.2 0.2 0.2 - Plum Fruit Fermentation Filtrate of Lactobacillus and Aspergillus 0.2 0.2 0.2 0.2 - oat flour extract 0.1 0.1 0.1 0.1 - acerola extract 0.1 0.1 0.1 0.1 0.1 cranberry extract 0.1 0.1 0.1 0.1 0.1 Low Sweet Blueberry Extract 0.1 0.1 0.1 0.1 0.1 orange extract 0.1 0.1 0.1 0.1 0.1 pomegranate extract 0.2 0.2 0.2 0.2 0.2 Beach Strawberry Extract 0.1 0.1 0.1 0.1 0.1 grape extract 0.1 0.1 0.1 0.1 0.1 Honeysuckle Extract 0.1 0.1 0.1 0.1 0.1 Chopi tree fruit extract 0.1 0.1 0.1 0.1 0.1 Halmi flower extract 0.1 0.1 0.1 0.1 0.1 Grapefruit Extract 0.2 0.2 0.2 0.2 0.2 Papaya Fruit Extract 0.1 0.1 0.1 0.1 0.1 chamomile flower oil - 0.1 0.1 - 0.1 tea tree leaf oil - 0.1 0.1 - 0.1 Decylglucoside 13 13 13 13 13 Sodium Lauroyl Glutamate 10 10 10 10 10 Coco-Glucoside 7 7 7 7 7 glycerin 7 7 7 7 7 Sodium Hyaluronate 8 8 8 8 8 potassium cocoate 5 5 5 5 5 Sodium Cocoyl Cethionate 4 4 4 4 4 1,2-Hexanediol One One One One One Stearic Acid 3 3 3 3 3 lauric acid 3 3 3 3 3 potassium hydroxide One One One One One Myristic Acid One One One One One betaine One One One One One Butylene Glycol One One One One One beta-glucan One One One One One allantoin 0.1 0.1 0.1 0.1 0.1 tocopherol 0.1 0.1 0.1 0.1 0.1 Dimethylsulfone 0.1 0.1 0.1 0.1 0.1 Disodium EDIT 0.1 0.1 0.1 0.1 0.1 Purified water to 100 to 100 to 100 to 100 to 100

[Experimental Example 1] Measurement of anti-acne effect

The antibacterial effect of the cleansing foams prepared in Examples 1 and 2 was tested. As the test bacteria, Propionibacterium acnes ATCC6919, an acne bacterium, was used.

In order to measure the antimicrobial activity, the strain P. acnes ATCC6919 was first cultured anaerobically in Reinforced Clostridial (RC) medium (Difco, USA) at 37°C for 48 hours (Bactron Anaerobic Chamber, Sheldon Manufacturing Inc., USA). The cultured P. acnes ATCC6919 was prepared in a suspension format, and the cleansing foam of each Example and Comparative Example was added to the RC medium to a concentration of 2.5% (w/v), and then vortex-mixed for 10 seconds. Thereafter, in an anaerobic environment (90% N ₂ , 5% H2, 5% CO ₂ ), incubated at 37° C. for 120 minutes, and the results obtained by measuring by the plate count technique are shown in Table 2 below.

Antibacterial activity against acne bacteria Test Items unit Results (after 30 seconds) Results (after 60 seconds) Example 1 log reduction 2.40 3.33 Example 2 log reduction 3.12 4.20 Comparative Example 1 log reduction 1.10 1.35 Comparative Example 2 log reduction 0.53 0.78 Comparative Example 3 log reduction 1.52 1.93

* Log reduction(LR)=log(A)-log(B)

- A: log value of the number of viable cells after a certain period of time in the control group

- B: log value of the number of viable cells after a certain period of time in the test group

1 or more: 90% or more, 2 or more: 99% or more, 3 or more: 99.9% or more, 4 or more: 99.99% or more, 5 or more: 99.999% or more

As shown in the test results in Table 2, all products of Examples of the present invention showed significantly superior results compared to Comparative Examples, and Comparative Example 2 showed the worst results, and Example 2 showed the best antibacterial activity. appear.

[Experimental Example 2] Confirmation of pigmentation inhibitory effect

In order to verify the pigmentation inhibitory effect of the samples prepared in Examples and Comparative Examples, an experiment was conducted in the following manner.

Forty healthy subjects were selected, and aluminum foil with 7 holes of 7 mm in diameter was attached to the lower arm of both arms in two rows, and 60mJ was used using an artificial sunlight irradiation device (ORIEL solar simulator 1000W) at a distance of 10cm from the arm. /cm ² The amount of light was irradiated. Before irradiation, the irradiation site was well washed with 70% ethanol aqueous solution. Samples of Examples and Comparative Examples were applied as a pair in the same row twice a day from 3 days before irradiation until 8 weeks after irradiation.

The panel was divided into 10 participants in group 1, and the test was conducted in 4 groups. For the determination of the whitening effect, the degree of pigmentation of Examples and Comparative Examples was visually determined for each, and the degree of inhibition of pigmentation of the formulation of the Example compared to the formulation of Comparative Example was evaluated as a distinct effect, effect, and no difference. Steps were evaluated, and the results are shown in Table 3 below.

pigmentation inhibitory effect formulation formulation distinct effect (persons) Effective (persons) No difference (persons) comparative example Comparative Example 1 2 2 16 Comparative Example 2 0 One 19 Comparative Example 3 5 5 10 Example Example 1 9 8 3 Example 2 13 6 One

As shown in Table 3, the samples of Examples of the present invention exhibit excellent skin whitening effect compared to Comparative Examples 1 to 3. As in Experimental Example 1, Comparative Example 2 showed the worst results, whereas Example 2 showed the best whitening effect.

Claims (5)

Hydroxyapatite, aloe vera leaf water, centella asiatica extract, kava kava extract, mistletoe extract, fermented plum fruit filtrate of Lactobacillus and Aspergillus, oat flour extract, acerola extract, cranberry extract, low sweet blueberry extract, orange extract , pomegranate extract, beach strawberry extract, grape extract, honeysuckle extract, chrysanthemum fruit extract, walnut flower extract, grapefruit extract, and papaya fruit extract as active ingredients. The method of claim 1,
A cleansing foam composition comprising further chamomile flower oil and tea tree leaf oil. 3. The method of claim 2,
Decyl glucoside, sodium lauroyl glutamate, coco-glucoside, glycerin, sodium hyaluronate, potassium cocoate, sodium cocoyl ethionate, 1,2-hexanediol, stearic acid, lauric acid, potassium Hydroxide, myristic acid, betaine, butylene glycol, beta-glucan, allantoin, tocopherol, dimethyl sulfone and disodium EDIT A cleansing foam composition comprising more. The method of claim 1,
Hydroxyapatite 0.1 to 5% by weight, Aloe vera leaf water 20 to 30% by weight, Centella asiatica extract 0.1 to 5% by weight, Kava kava extract 0.1 to 5% by weight, Mistletoe extract 0.1 to 1% by weight, Lactobacillus and Aspergillus Plum tree fruit fermentation filtrate 0.1 to 1% by weight, oat flour extract 0.1 to 1% by weight, acerola extract 0.1 to 1% by weight, cranberry extract 0.1 to 1% by weight, low sweet blueberry extract 0.1 to 1% by weight, orange extract 0.1 to 1% by weight, pomegranate extract 0.1 to 1% by weight, beech strawberry extract 0.1 to 1% by weight, grape extract 0.1 to 1% by weight, honeysuckle extract 0.1 to 1% by weight, chrysanthemum extract 0.1 to 1% by weight , A cleansing foam composition containing 0.1 to 1% by weight of a wild flower extract, 0.1 to 1% by weight of a grapefruit extract, and 0.1 to 1% by weight of a papaya fruit extract as active ingredients. 4. The method of claim 3,
Chamomile flower oil 0.1~1% by weight, tea tree leaf oil 0.1~1% by weight, decylglucoside 10~15% by weight, sodium lauroyl glutamate 5~15% by weight, coco-glucoside 5~10% by weight, glycerin 5~ 10 wt%, sodium hyaluronate 5-10 wt%, potassium cocoate 3-8 wt%, sodium cocoylethionate 2-6 wt%, 1,2-hexanediol 0.1-2 wt%, Stearic acid 1-5% by weight, lauric acid 1-5% by weight, potassium hydroxide 0.1-5% by weight, myristic acid 0.1-5% by weight, betaine 0.1-5% by weight, butylene glycol 0.1 ~5% by weight, beta-glucan 0.1~5% by weight, allantoin 0.1~1% by weight, tocopherol 0.1~1% by weight, dimethyl sulfone 0.1~1% by weight, and disodium EDTA 0.1~1% by weight. Cleansing foam composition, characterized in that.