KR20210137422A - 티로신 키나아제 억제제로서의 퀴나졸린 유도체, 조성물, 이들의 제조 방법 및 이들의 용도 - Google Patents

티로신 키나아제 억제제로서의 퀴나졸린 유도체, 조성물, 이들의 제조 방법 및 이들의 용도 Download PDF

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KR20210137422A
KR20210137422A KR1020217011604A KR20217011604A KR20210137422A KR 20210137422 A KR20210137422 A KR 20210137422A KR 1020217011604 A KR1020217011604 A KR 1020217011604A KR 20217011604 A KR20217011604 A KR 20217011604A KR 20210137422 A KR20210137422 A KR 20210137422A
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amino acid
halogen
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알렉산더 플로어
알렉산더 메이웨그
조지 트레이너
데이비드 엠 엡스타인
매튜 오코너
엘리자베스 벅
루카 아리스타
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블랙 다이아몬드 테라퓨틱스, 인코포레이티드
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    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
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KR1020217011604A 2018-09-25 2019-09-24 티로신 키나아제 억제제로서의 퀴나졸린 유도체, 조성물, 이들의 제조 방법 및 이들의 용도 Ceased KR20210137422A (ko)

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US201862736293P 2018-09-25 2018-09-25
US62/736,293 2018-09-25
US201962903592P 2019-09-20 2019-09-20
US62/903,592 2019-09-20
PCT/US2019/052784 WO2020068867A1 (en) 2018-09-25 2019-09-24 Quinazoline derivatives as tyrosine kinase inhibitor, compositions, methods of making them and their use

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CN (1) CN113382986A (https=)
AU (1) AU2019346550A1 (https=)
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AU2019346550A1 (en) 2018-09-25 2021-04-22 Black Diamond Therapeutics, Inc. Quinazoline derivatives as tyrosine kinase inhibitor, compositions, methods of making them and their use
EP4013749B1 (en) 2019-08-15 2026-03-11 Black Diamond Therapeutics, Inc. Alkynyl quinazoline compounds
WO2021195206A1 (en) * 2020-03-24 2021-09-30 Black Diamond Therapeutics, Inc. Polymorphic forms and related uses
AR122450A1 (es) * 2020-05-08 2022-09-14 Lilly Co Eli Compuestos de (trifluorometil)pirimidin-2-amina
US20230265098A1 (en) * 2020-07-02 2023-08-24 Enliven Therapeutics, Inc. Alkyne quinazoline derivatives as inhibitors of erbb2
US20230271936A1 (en) * 2020-08-10 2023-08-31 Abbisko Therapeutics Co., Ltd Efgr inhibitor, preparation method therefor and application thereof
WO2022040377A1 (en) 2020-08-20 2022-02-24 Black Diamond Therapeutics, Inc. Methods for preparing quinazoline derivatives
AU2021347232A1 (en) 2020-09-23 2023-04-27 Erasca, Inc. Tricyclic pyridones and pyrimidones
WO2022076671A1 (en) * 2020-10-08 2022-04-14 Black Diamond Therapeutics, Inc. Method of treating cancers using quinazoline derivatives
CN116710096A (zh) * 2020-11-02 2023-09-05 黑钻治疗公司 用炔取代的喹唑啉衍生物治疗癌症的方法
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