KR20210107053A - 박테리아 전달 비히클에서 사용을 위한 분지형 수용체 결합 다수-서브유닛 단백질 복합체 - Google Patents

박테리아 전달 비히클에서 사용을 위한 분지형 수용체 결합 다수-서브유닛 단백질 복합체 Download PDF

Info

Publication number
KR20210107053A
KR20210107053A KR1020217022651A KR20217022651A KR20210107053A KR 20210107053 A KR20210107053 A KR 20210107053A KR 1020217022651 A KR1020217022651 A KR 1020217022651A KR 20217022651 A KR20217022651 A KR 20217022651A KR 20210107053 A KR20210107053 A KR 20210107053A
Authority
KR
South Korea
Prior art keywords
virus
rbp
ala
seq
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020217022651A
Other languages
English (en)
Korean (ko)
Inventor
헤수스 페르난데스-로드리게스
Original Assignee
엘리고 바이오사이언스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/696,769 external-priority patent/US11661443B2/en
Application filed by 엘리고 바이오사이언스 filed Critical 엘리고 바이오사이언스
Publication of KR20210107053A publication Critical patent/KR20210107053A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10342—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020217022651A 2018-12-21 2019-12-23 박테리아 전달 비히클에서 사용을 위한 분지형 수용체 결합 다수-서브유닛 단백질 복합체 Withdrawn KR20210107053A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862783258P 2018-12-21 2018-12-21
US62/783,258 2018-12-21
US201962802777P 2019-02-08 2019-02-08
US62/802,777 2019-02-08
US16/696,769 US11661443B2 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
EPPCT/EP2019/082640 2019-11-26
US16/696,769 2019-11-26
PCT/EP2019/082640 WO2020109339A1 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
PCT/EP2019/086990 WO2020128108A1 (en) 2018-12-21 2019-12-23 Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles

Publications (1)

Publication Number Publication Date
KR20210107053A true KR20210107053A (ko) 2021-08-31

Family

ID=71101098

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217022651A Withdrawn KR20210107053A (ko) 2018-12-21 2019-12-23 박테리아 전달 비히클에서 사용을 위한 분지형 수용체 결합 다수-서브유닛 단백질 복합체

Country Status (7)

Country Link
EP (1) EP3898953A1 (https=)
JP (1) JP2022514700A (https=)
KR (1) KR20210107053A (https=)
CN (1) CN113498435A (https=)
CA (1) CA3120160A1 (https=)
IL (1) IL283796A (https=)
WO (1) WO2020128108A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11584781B2 (en) 2019-12-30 2023-02-21 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
TR202014396A2 (tr) * 2020-09-10 2022-03-21 Univ Yildiz Teknik Mikroorganizma hedefli, antimikrobiyal bileşen/bileşenler içeren nanoformülasyonlar.
WO2022144381A1 (en) * 2020-12-30 2022-07-07 Eligo Bioscience Microbiome modulation of a host by delivery of dna payloads with minimized spread
JP2024520940A (ja) * 2021-05-12 2024-05-27 エリゴ・バイオサイエンス 産生細菌細胞及び産生方法におけるその使用
EP4342538A1 (en) * 2022-09-20 2024-03-27 Technische Universität München Simultaneous production of structural proteins from heterologous bacteriophage in cell-free expression system
EP4615856A1 (en) * 2022-11-10 2025-09-17 Laboratory Corporation of America Holdings Synthetic phage with recombinant tail-spike proteins and related methods
CN116003531B (zh) * 2022-12-28 2023-09-05 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10660943B2 (en) 2013-02-07 2020-05-26 The Rockefeller University Sequence specific antimicrobials
EP3234136B1 (en) * 2014-12-16 2024-08-21 C3J Therapeutics, Inc. Compositions of and methods for in vitro viral genome engineering

Also Published As

Publication number Publication date
CN113498435A (zh) 2021-10-12
EP3898953A1 (en) 2021-10-27
JP2022514700A (ja) 2022-02-14
CA3120160A1 (en) 2020-06-25
WO2020128108A1 (en) 2020-06-25
IL283796A (en) 2021-07-29

Similar Documents

Publication Publication Date Title
JP7635286B2 (ja) 微生物集団の送達用に最適化されたベクター
KR20210100119A (ko) 박테리아 전달 비히클에서 사용을 위한 키메라 수용체 결합 단백질
KR20210107053A (ko) 박테리아 전달 비히클에서 사용을 위한 분지형 수용체 결합 다수-서브유닛 단백질 복합체
KR20220164757A (ko) 마이크로바이옴-연관 질환 또는 장애의 예방, 치료 또는 치유를 위한 마이크로바이옴의 유전자 요법에 의한 미생물총 기능의 조절
US11208437B2 (en) Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles
KR20220122702A (ko) Dna 페이로드의 생체내 전달을 위한 박테리아 전달 비히클
KR20210141999A (ko) Dna-결합 리프레서를 사용한 원핵생물 세포의 전사 제어
CN117616118A (zh) 生产细菌细胞及其在生产方法中的用途
US20210196828A1 (en) Bacterial delivery vehicles for in vivo delivery of a dna payload
KR20240020271A (ko) 생산 박테리아 세포 및 제조 방법에서 이의 용도
US20220064223A1 (en) Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles
KR20230127265A (ko) 최소 확산으로 dna 페이로드의 전달을 통한 숙주의마이크로바이옴 조절
US20230134572A1 (en) Chimeric receptor binding proteins resistant to proteolytic degradation
HK40111917A (en) Chimeric receptor binding proteins for use in bacterial delivery vehicles
CN116940677A (zh) 通过以最小传播递送dna有效载荷对宿主的微生物组调节

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

PC1202 Submission of document of withdrawal before decision of registration

St.27 status event code: N-1-6-B10-B11-nap-PC1202