JP2022514700A - 細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体 - Google Patents

細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体 Download PDF

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JP2022514700A
JP2022514700A JP2021536201A JP2021536201A JP2022514700A JP 2022514700 A JP2022514700 A JP 2022514700A JP 2021536201 A JP2021536201 A JP 2021536201A JP 2021536201 A JP2021536201 A JP 2021536201A JP 2022514700 A JP2022514700 A JP 2022514700A
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virus
rbp
seq
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lambda
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JPWO2020128108A5 (https=
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ヘスス・フェルナンデス－ロドリゲス
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エリゴ・バイオサイエンス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10342—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021536201A 2018-12-21 2019-12-23 細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体 Pending JP2022514700A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862783258P 2018-12-21 2018-12-21
US62/783,258 2018-12-21
US201962802777P 2019-02-08 2019-02-08
US62/802,777 2019-02-08
US16/696,769 US11661443B2 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
EPPCT/EP2019/082640 2019-11-26
US16/696,769 2019-11-26
PCT/EP2019/082640 WO2020109339A1 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
PCT/EP2019/086990 WO2020128108A1 (en) 2018-12-21 2019-12-23 Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles

Publications (3)

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JP2022514700A true JP2022514700A (ja) 2022-02-14
JPWO2020128108A5 JPWO2020128108A5 (https=) 2023-01-10
JP2022514700A5 JP2022514700A5 (https=) 2023-01-10

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JP2021536201A Pending JP2022514700A (ja) 2018-12-21 2019-12-23 細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体

Country Status (7)

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EP (1) EP3898953A1 (https=)
JP (1) JP2022514700A (https=)
KR (1) KR20210107053A (https=)
CN (1) CN113498435A (https=)
CA (1) CA3120160A1 (https=)
IL (1) IL283796A (https=)
WO (1) WO2020128108A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11584781B2 (en) 2019-12-30 2023-02-21 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
TR202014396A2 (tr) * 2020-09-10 2022-03-21 Univ Yildiz Teknik Mikroorganizma hedefli, antimikrobiyal bileşen/bileşenler içeren nanoformülasyonlar.
WO2022144381A1 (en) * 2020-12-30 2022-07-07 Eligo Bioscience Microbiome modulation of a host by delivery of dna payloads with minimized spread
JP2024520940A (ja) * 2021-05-12 2024-05-27 エリゴ・バイオサイエンス 産生細菌細胞及び産生方法におけるその使用
EP4342538A1 (en) * 2022-09-20 2024-03-27 Technische Universität München Simultaneous production of structural proteins from heterologous bacteriophage in cell-free expression system
EP4615856A1 (en) * 2022-11-10 2025-09-17 Laboratory Corporation of America Holdings Synthetic phage with recombinant tail-spike proteins and related methods
CN116003531B (zh) * 2022-12-28 2023-09-05 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10660943B2 (en) 2013-02-07 2020-05-26 The Rockefeller University Sequence specific antimicrobials
EP3234136B1 (en) * 2014-12-16 2024-08-21 C3J Therapeutics, Inc. Compositions of and methods for in vitro viral genome engineering

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CELL SYSTEMS, vol. 1, JPN6023047274, 2015, pages 187 - 196, ISSN: 0005199583 *
J. MOL. BIOL., vol. 371, JPN6023047279, 2007, pages 836 - 849, ISSN: 0005347886 *
MOLECULAR MICROBIOLOGY, vol. 105, no. 3, JPN6023047275, 2017, pages 385 - 398, ISSN: 0005347888 *
TRENDS IN MICROBIOLOGY, vol. 27, no. 1, JPN6023047276, 17 December 2018 (2018-12-17), pages 51 - 63, ISSN: 0005347890 *
VIROLOGY, vol. 507, JPN6023047278, 2017, pages 263 - 266, ISSN: 0005347887 *
VIRUSES, vol. 8, JPN6023047277, 2016, pages 1 - 21, ISSN: 0005347889 *

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Publication number Publication date
CN113498435A (zh) 2021-10-12
EP3898953A1 (en) 2021-10-27
CA3120160A1 (en) 2020-06-25
WO2020128108A1 (en) 2020-06-25
KR20210107053A (ko) 2021-08-31
IL283796A (en) 2021-07-29

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