KR20210094509A - 재조합 점액종 바이러스 및 이의 용도 - Google Patents

재조합 점액종 바이러스 및 이의 용도 Download PDF

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KR20210094509A
KR20210094509A KR1020217006855A KR20217006855A KR20210094509A KR 20210094509 A KR20210094509 A KR 20210094509A KR 1020217006855 A KR1020217006855 A KR 1020217006855A KR 20217006855 A KR20217006855 A KR 20217006855A KR 20210094509 A KR20210094509 A KR 20210094509A
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cancer
virus
therapy
oncolytic virus
melanoma
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Korean (ko)
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제프 키에페
라몬 모레노
스파이로 무스
에릭 바르티
Original Assignee
무스크 파운데이션 포 리서치 디벨롭먼트
시스템즈 온콜로지, 엘엘씨
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Publication of KR20210094509A publication Critical patent/KR20210094509A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
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    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
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    • A61K9/0048—Eye, e.g. artificial tears
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Dermatology (AREA)
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  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Inorganic Chemistry (AREA)
KR1020217006855A 2018-08-16 2019-08-16 재조합 점액종 바이러스 및 이의 용도 Ceased KR20210094509A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862718990P 2018-08-16 2018-08-16
US62/718,990 2018-08-16
US201862741404P 2018-10-04 2018-10-04
US62/741,404 2018-10-04
US201862754622P 2018-11-02 2018-11-02
US62/754,622 2018-11-02
US201962813375P 2019-03-04 2019-03-04
US62/813,375 2019-03-04
PCT/US2019/046823 WO2020037206A1 (en) 2018-08-16 2019-08-16 Recombinant myxoma viruses and uses thereof

Publications (1)

Publication Number Publication Date
KR20210094509A true KR20210094509A (ko) 2021-07-29

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KR1020217006855A Ceased KR20210094509A (ko) 2018-08-16 2019-08-16 재조합 점액종 바이러스 및 이의 용도

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Country Link
US (1) US20210196771A1 (https=)
EP (1) EP3837354A4 (https=)
JP (1) JP2021533789A (https=)
KR (1) KR20210094509A (https=)
CN (1) CN112771157A (https=)
AU (1) AU2019321667A1 (https=)
BR (1) BR112021002639A2 (https=)
CA (1) CA3109216A1 (https=)
IL (1) IL280854A (https=)
MX (1) MX2021001883A (https=)
WO (1) WO2020037206A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210031485A (ko) 2018-07-13 2021-03-19 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 Tnf를 발현하는 점액종 바이러스로 암을 치료하는 방법
US11591616B1 (en) 2019-04-22 2023-02-28 Colorado State University Research Foundation Apoptotic upregulation by myxoma virus expressing walleye dermal sarcoma virus orfC
BR112022000928A2 (pt) 2019-07-19 2022-03-08 Seneca Therapeutics Inc Terapia oncolítica do vírus seneca valley de segunda geração: composições e métodos da mesma
TW202122411A (zh) 2019-09-02 2021-06-16 美國亞利桑那州立大學亞利桑那州評議委員會 以黏液瘤(myxoma)病毒治療癌症之新穎溶瘤病毒平臺
EP4041266A1 (en) * 2019-10-10 2022-08-17 Arizona Board of Regents on behalf of Arizona State University Oncolytic virus comprising immunomodulatory transgenes and uses thereof
CA3168771A1 (en) * 2020-02-20 2021-08-26 Eric Bartee Recombinant myxoma viruses and uses thereof
US12071633B2 (en) 2020-10-13 2024-08-27 Kriya Therapeutics, Inc. Viral vector constructs for delivery of nucleic acids encoding cytokines and uses thereof for treating cancer
WO2022139440A1 (ko) * 2020-12-22 2022-06-30 바이로큐어 주식회사 신규한 재조합 믹소마바이러스 및 이의 용도
EP4281549A4 (en) * 2021-01-19 2025-05-07 Seneca Therapeutics, Inc. ONCOLYTIC THERAPY COMPOSITIONS CONTAINING SENECA VALLEY VIRUS AND METHODS THEREFOR
JP2024508920A (ja) * 2021-03-01 2024-02-28 オンコミクス セラピューティクス，インク． 多武装の粘液腫ウイルス
EP4490271A1 (en) * 2022-03-10 2025-01-15 City of Hope Membrane-bound il-12 for cellular immunotherapy
JPWO2024111633A1 (https=) * 2022-11-24 2024-05-30

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2670804A1 (en) * 2006-05-19 2007-11-29 Sanofi Pasteur Inc. Immunological composition
WO2008070367A2 (en) * 2006-11-01 2008-06-12 Facet Biotech Corporation Mammalian cell-based immunoglobulin display libraries
FR2946536B1 (fr) * 2009-06-11 2011-07-29 Agronomique Inst Nat Rech Utilisation d'une souche attenuee de myxoma virus comme oncolytique
RU2696312C2 (ru) * 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
ES2924402T3 (es) * 2015-10-02 2022-10-06 Symphogen As Anticuerpos anti-PD-1 y composiciones
HUE048265T2 (hu) * 2015-10-27 2020-08-28 Pharmassist Ltd Eljárás PD-L1 mennyiségi meghatározására
WO2018049248A1 (en) * 2016-09-09 2018-03-15 Icellhealth Consulting Llc Oncolytic virus equipped with bispecific engager molecules

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WO2020037206A1 (en) 2020-02-20
BR112021002639A2 (pt) 2021-05-11
AU2019321667A1 (en) 2021-03-04
MX2021001883A (es) 2021-07-15
EP3837354A1 (en) 2021-06-23
CN112771157A (zh) 2021-05-07
JP2021533789A (ja) 2021-12-09
CA3109216A1 (en) 2020-02-20
IL280854A (en) 2021-04-29
US20210196771A1 (en) 2021-07-01
WO2020037206A4 (en) 2020-05-14
EP3837354A4 (en) 2022-06-01

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