KR20210068079A - Cd3 및 cd137에 결합할 수 있지만 동시에는 결합하지 않는 항원 결합 분자 - Google Patents

Cd3 및 cd137에 결합할 수 있지만 동시에는 결합하지 않는 항원 결합 분자 Download PDF

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KR20210068079A
KR20210068079A KR1020217012569A KR20217012569A KR20210068079A KR 20210068079 A KR20210068079 A KR 20210068079A KR 1020217012569 A KR1020217012569 A KR 1020217012569A KR 20217012569 A KR20217012569 A KR 20217012569A KR 20210068079 A KR20210068079 A KR 20210068079A
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amino acid
seq
acid sequence
complementarity determining
determining region
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슈 원 사만사 호
슈 펑
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추가이 세이야쿠 가부시키가이샤
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KR1020217012569A 2018-09-28 2019-09-27 Cd3 및 cd137에 결합할 수 있지만 동시에는 결합하지 않는 항원 결합 분자 Withdrawn KR20210068079A (ko)

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JP2018185120 2018-09-28
JPJP-P-2018-185120 2018-09-28
JP2019104308 2019-06-04
JPJP-P-2019-104308 2019-06-04
PCT/JP2019/038138 WO2020067419A1 (en) 2018-09-28 2019-09-27 Antigen-binding molecules capable of binding cd3 and cd137 but not simultaneously

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US (1) US20210388087A1 (https=)
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JP (3) JP7519990B2 (https=)
KR (1) KR20210068079A (https=)
CN (1) CN113166247A (https=)
AU (1) AU2019347412A1 (https=)
BR (1) BR112021005722A2 (https=)
CA (1) CA3114154A1 (https=)
CL (1) CL2021000739A1 (https=)
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PE (1) PE20211072A1 (https=)
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KR102813659B1 (ko) 2013-11-11 2025-05-28 추가이 세이야쿠 가부시키가이샤 개변된 항체 가변영역을 포함하는 항원 결합 분자
TWI831044B (zh) 2014-11-11 2024-02-01 日商中外製藥股份有限公司 抗原結合分子、包含抗原結合分子的醫藥組合物以及製造及選擇抗原結合分子之方法
TW201938194A (zh) 2017-12-05 2019-10-01 日商中外製藥股份有限公司 包含結合cd3及cd137的改變的抗體可變區之抗原結合分子
JP7314146B2 (ja) 2017-12-28 2023-07-25 中外製薬株式会社 細胞傷害誘導治療剤
MX2021000827A (es) 2018-08-03 2021-03-25 Chugai Pharmaceutical Co Ltd Molecula de union a antigeno que contiene dos dominios de union a antigeno que estan enlazados entre si.
US12509524B2 (en) 2018-09-28 2025-12-30 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule comprising altered antibody variable region
MX2022000111A (es) 2019-07-10 2022-02-10 Chugai Pharmaceutical Co Ltd Moleculas de union a claudina-6 y usos de las mismas.
MX2022011387A (es) * 2020-03-31 2022-10-10 Chugai Pharmaceutical Co Ltd Metodo para producir moleculas de union a antigeno multiespecificas.
CR20220541A (es) 2020-03-31 2022-11-28 Chugai Pharmaceutical Co Ltd Moléculas de unión al antígeno multiespecíficas dirigidas a ligando de tipo delta 3 (dll3) y sus usos
TW202204410A (zh) * 2020-03-31 2022-02-01 日商中外製藥股份有限公司 免疫活化多特異性抗原結合分子及其用途
WO2023036043A1 (zh) * 2021-09-09 2023-03-16 广东东阳光药业有限公司 抗癌结合分子及其应用
WO2023053272A1 (en) * 2021-09-29 2023-04-06 Chugai Seiyaku Kabushiki Kaisha Uses of dll3-targeting multispecific antigen-binding molecules
WO2023053282A1 (ja) * 2021-09-29 2023-04-06 中外製薬株式会社 がんの治療に用いるための細胞傷害誘導治療剤
JP7470760B2 (ja) * 2021-09-29 2024-04-18 中外製薬株式会社 がんの治療に用いるための細胞傷害誘導治療剤
JP7557922B2 (ja) 2021-09-29 2024-09-30 中外製薬株式会社 Ｄｌｌ３標的多重特異性抗原結合分子の使用
WO2024114676A1 (zh) * 2022-11-29 2024-06-06 江苏恒瑞医药股份有限公司 Cldn18.2/4-1bb结合蛋白及其医药用途

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