KR20210042120A - 항체-약물 콘주게이트와 튜불린 저해제의 조합 - Google Patents
항체-약물 콘주게이트와 튜불린 저해제의 조합 Download PDFInfo
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- KR20210042120A KR20210042120A KR1020217006189A KR20217006189A KR20210042120A KR 20210042120 A KR20210042120 A KR 20210042120A KR 1020217006189 A KR1020217006189 A KR 1020217006189A KR 20217006189 A KR20217006189 A KR 20217006189A KR 20210042120 A KR20210042120 A KR 20210042120A
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- antibody
- pharmaceutical composition
- amino acid
- drug conjugate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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| IL288485B2 (en) * | 2019-05-29 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-TROP2 antibody conjugates - a drug for use in cancer treatment |
| WO2021200131A1 (ja) * | 2020-03-30 | 2021-10-07 | 国立研究開発法人国立がん研究センター | 抗体薬物複合体 |
| KR20240038138A (ko) | 2020-07-13 | 2024-03-22 | 리제너론 파마슈티칼스 인코포레이티드 | 단백질에서 글루타민 잔기에 접합된 캄토테신 유사체 및 그의 용도 |
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| WO2022099762A1 (zh) * | 2020-11-12 | 2022-05-19 | 博瑞生物医药(苏州)股份有限公司 | 一种抗体偶联物中间体及其制备方法 |
| EP4265274B1 (en) * | 2020-12-18 | 2025-03-19 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | B7-h3 targeting antibody-drug conjugate, and preparation method therefor and use thereof |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| TW202320858A (zh) | 2021-07-19 | 2023-06-01 | 美商薩諾管理公司 | 免疫接合物及方法 |
| CN117881431A (zh) * | 2021-08-24 | 2024-04-12 | 昆山新蕴达生物科技有限公司 | 一种由可断裂连接子偶联的抗体偶联药物 |
| WO2023042097A1 (en) * | 2021-09-15 | 2023-03-23 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate for use in methods of treating chemotherapy-resistant cancer |
| CN119255825A (zh) * | 2022-05-24 | 2025-01-03 | 第一三共株式会社 | 抗-cdh6抗体-药物缀合物的剂量方案 |
| CN118955615B (zh) * | 2022-07-05 | 2026-01-30 | 上海药明合联生物技术有限公司 | 偶联连接子 |
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| EA202190471A1 (ru) | 2021-05-24 |
| JP2024075668A (ja) | 2024-06-04 |
| TW202019487A (zh) | 2020-06-01 |
| JPWO2020031936A1 (ja) | 2021-08-10 |
| BR112021001750A2 (pt) | 2021-04-27 |
| AU2025226765A1 (en) | 2025-09-25 |
| CA3108754A1 (en) | 2020-02-13 |
| US12497465B2 (en) | 2025-12-16 |
| EP3834843A4 (en) | 2022-05-11 |
| WO2020031936A1 (ja) | 2020-02-13 |
| JP7458981B2 (ja) | 2024-04-01 |
| CN112512587A (zh) | 2021-03-16 |
| AU2019320336A1 (en) | 2021-03-04 |
| US20210290775A1 (en) | 2021-09-23 |
| AU2019320336B2 (en) | 2025-06-05 |
| JP2024178243A (ja) | 2024-12-24 |
| EP3834843A1 (en) | 2021-06-16 |
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