KR20210032449A - 면역조작된 만능성 줄기세포로부터 유래된 키메라 항원 수용체 t 세포 - Google Patents
면역조작된 만능성 줄기세포로부터 유래된 키메라 항원 수용체 t 세포 Download PDFInfo
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| WO2023008918A1 (ko) * | 2021-07-28 | 2023-02-02 | 의료법인 성광의료재단 | B2m 유전자의 발현이 저해된 유전적으로 조작된 줄기세포 및 이의 이용방법 |
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| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| WO2020231882A2 (en) | 2019-05-10 | 2020-11-19 | The Regents Of The University Of California | Modified pluripotent cells |
| AU2021207810A1 (en) * | 2020-01-13 | 2022-08-04 | Sana Biotechnology, Inc. | Modification of blood type antigens |
| MX2022011831A (es) * | 2020-03-25 | 2023-01-04 | Sana Biotechnology Inc | Células neurales hipoinmunogénicas para el tratamiento de trastornos y afecciones neurológicas. |
| CN115916962A (zh) * | 2020-04-27 | 2023-04-04 | 萨那生物技术股份有限公司 | 低免疫原性细胞的重复给药 |
| EP4149525A4 (en) * | 2020-05-15 | 2024-08-28 | Rxcell Inc. | HYPOIMMUNOGENIC CELLS AND THEIR USES IN IMMUNE RESPONSES |
| IL300516A (en) * | 2020-08-13 | 2023-04-01 | Sana Biotechnology Inc | Methods for treating susceptible patients with hypoimmunogenic cells, and related methods and compounds |
| US11591381B2 (en) | 2020-11-30 | 2023-02-28 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CA3200509A1 (en) * | 2020-12-31 | 2022-07-07 | Sonja SCHREPFER | Methods and compositions for modulating car-t activity |
| US20250269022A1 (en) * | 2021-05-06 | 2025-08-28 | Mayo Foundation For Medical Education And Research | Assessing and treating cancer |
| BR112023024231A2 (pt) | 2021-05-19 | 2024-01-30 | Sana Biotechnology Inc | Células t primárias rhd negativas hipoimunogênicas |
| AU2022283291A1 (en) | 2021-05-27 | 2023-11-02 | Sana Biotechnology, Inc. | Hypoimmunogenic cells comprising engineered hla-e or hla-g |
| KR20240046319A (ko) | 2021-07-14 | 2024-04-08 | 사나 바이오테크놀로지, 인크. | 저면역원성 세포에서의 y 염색체-연결 항원의 변경된 발현 |
| MX2024000713A (es) * | 2021-07-16 | 2024-03-25 | Sana Biotechnology Inc | Vectores policistrónicos para terapias a base de células. |
| TW202321435A (zh) | 2021-08-11 | 2023-06-01 | 美商薩那生物科技公司 | 用於改變低免疫原性細胞中之基因表現之可誘導系統 |
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| WO2023019226A1 (en) | 2021-08-11 | 2023-02-16 | Sana Biotechnology, Inc. | Genetically modified cells for allogeneic cell therapy |
| AU2022325231A1 (en) | 2021-08-11 | 2024-02-08 | Sana Biotechnology, Inc. | Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions |
| JP2024535677A (ja) | 2021-08-11 | 2024-10-02 | サナ バイオテクノロジー,インコーポレイテッド | 即時血液媒介性炎症反応を減少させるための同種細胞療法を目的とした遺伝子改変細胞 |
| WO2023069790A1 (en) | 2021-10-22 | 2023-04-27 | Sana Biotechnology, Inc. | Methods of engineering allogeneic t cells with a transgene in a tcr locus and associated compositions and methods |
| MX2024007528A (es) | 2021-12-23 | 2024-08-30 | Sana Biotechnology Inc | Linfocitos t del receptor de antígeno quimérico (car) para el tratamiento de enfermedades autoinmunitarias y métodos asociados. |
| KR20240142624A (ko) * | 2022-01-10 | 2024-09-30 | 사나 바이오테크놀로지, 인크. | 만능줄기세포에서 분화된 면역저하 베타세포 및 관련 용도 및 방법 |
| WO2023154578A1 (en) | 2022-02-14 | 2023-08-17 | Sana Biotechnology, Inc. | Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells |
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| CN119213117A (zh) * | 2022-04-07 | 2024-12-27 | 菲特治疗公司 | 用于同种异体细胞疗法的参与免疫识别途径的隐形策略 |
| EP4504914A4 (en) | 2022-04-08 | 2026-04-29 | Fate Therapeutics Inc | Cells having solid tumor targeting backbone and use thereof |
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| CA3254552A1 (en) * | 2022-04-28 | 2023-11-02 | Allogene Therapeutics Inc. | METHODS FOR ANALYZING DONOR CELLS |
| JP2025518125A (ja) * | 2022-05-25 | 2025-06-12 | マルコルム,トーマス | 生体模倣型ナノ小胞を作製するための低免疫原性細胞 |
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| EP4547825A1 (en) | 2022-07-01 | 2025-05-07 | Novo Nordisk A/S | Enhancing neuronal differentiation of ventral midbrain neural progenitor cells |
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| CN118207165B (zh) * | 2022-12-07 | 2026-03-20 | 士泽生物医药(苏州)有限公司 | 一种表达stc1的通用型细胞及其制备方法 |
| CN115612673A (zh) * | 2022-12-14 | 2023-01-17 | 卡瑞济(北京)生命科技有限公司 | 一种改善car-t细胞群的持久性的方法 |
| WO2024183750A1 (en) * | 2023-03-07 | 2024-09-12 | Qihan Hong Kong Limited | A novel immune cell and use thereof for treating diseases |
| WO2025003393A1 (en) | 2023-06-30 | 2025-01-02 | Novo Nordisk A/S | Enhancing neuronal differentiation of neural progenitor cells |
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| AU2001297880B2 (en) * | 2000-11-30 | 2007-05-31 | Stemron Inc. | Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same |
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| EP3134515B1 (en) * | 2014-04-24 | 2019-03-27 | Board of Regents, The University of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| EP3294342A4 (en) * | 2015-05-08 | 2018-11-07 | President and Fellows of Harvard College | Universal donor stem cells and related methods |
| GB201518136D0 (en) * | 2015-10-14 | 2015-11-25 | Glaxosmithkline Ip Dev Ltd | Novel chimeric antigen receptors |
| JP6928604B2 (ja) * | 2015-11-04 | 2021-09-01 | フェイト セラピューティクス,インコーポレイテッド | 万能性細胞のゲノム改変 |
| CN110177869A (zh) * | 2017-01-13 | 2019-08-27 | 加利福尼亚大学董事会 | 免疫改造的多能细胞 |
| US20200109364A1 (en) * | 2018-05-31 | 2020-04-09 | Washington University | Methods for genome-editing and activation of cells |
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| WO2023008918A1 (ko) * | 2021-07-28 | 2023-02-02 | 의료법인 성광의료재단 | B2m 유전자의 발현이 저해된 유전적으로 조작된 줄기세포 및 이의 이용방법 |
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