KR20210016431A - 암 치료용 키메라 항원 수용체 t 세포 (car-t) - Google Patents
암 치료용 키메라 항원 수용체 t 세포 (car-t) Download PDFInfo
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US201862678878P | 2018-05-31 | 2018-05-31 | |
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US201962799513P | 2019-01-31 | 2019-01-31 | |
US62/799,513 | 2019-01-31 | ||
PCT/US2019/035010 WO2019232444A1 (en) | 2018-05-31 | 2019-05-31 | Chimeric antigen receptor t cells (car-t) for the treatment of cancer |
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KR20210016431A true KR20210016431A (ko) | 2021-02-15 |
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EP (1) | EP3802798A4 (de) |
JP (1) | JP7542854B2 (de) |
KR (1) | KR20210016431A (de) |
CN (1) | CN112912493A (de) |
AU (1) | AU2019279021A1 (de) |
CA (1) | CA3101505A1 (de) |
IL (1) | IL279063A (de) |
SG (1) | SG11202011383VA (de) |
WO (1) | WO2019232444A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
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US11253546B2 (en) | 2014-12-15 | 2022-02-22 | The Regents Of The University Of California | Bispecific OR-gate chimeric antigen receptor responsive to CD19 and CD20 |
CN110616188B (zh) * | 2018-06-20 | 2023-05-09 | 上海隆耀生物科技有限公司 | 一种通用型car-t细胞及其制备方法和应用 |
WO2020224606A1 (zh) | 2019-05-07 | 2020-11-12 | 亘喜生物科技(上海)有限公司 | 靶向bcma的工程化免疫细胞及其用途 |
WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
WO2021050862A1 (en) * | 2019-09-13 | 2021-03-18 | Memorial Sloan-Kettering Cancer Center | Antigen recognizing receptors targeting cd371 and uses thereof |
BR112022025381A2 (pt) | 2020-06-11 | 2023-01-24 | Provention Bio Inc | Métodos e composições para prevenir diabetes tipo 1 |
CN113214396B (zh) * | 2020-07-31 | 2022-04-19 | 北京市神经外科研究所 | 抗tim3的单链抗体及其在制备治疗肿瘤的药物中的用途 |
JP2023541458A (ja) * | 2020-09-14 | 2023-10-02 | ブイオーアール バイオファーマ インコーポレーテッド | Cd5修飾のための化合物および方法 |
CA3199621A1 (en) * | 2020-10-26 | 2022-05-05 | Memorial Sloan-Kettering Cancer Center | Cells with cd70 knockout and uses for immunotherapy |
WO2022098756A1 (en) * | 2020-11-03 | 2022-05-12 | WUGEN, Inc. | Chimeric antigen receptor cell therapy |
EP4408469A1 (de) * | 2021-09-29 | 2024-08-07 | Modex Therapeutics, Inc. | Antigenbindende polypeptide, antigenbindende polypeptidkomplexe und verfahren zur verwendung davon |
CN114369622A (zh) * | 2021-12-31 | 2022-04-19 | 西安桑尼赛尔生物医药有限公司 | 同时靶向cd7和cd19的双特异通用型car-t细胞及其制备方法 |
CN114317607B (zh) * | 2021-12-31 | 2024-08-02 | 苏州桑尼赛尔生物医药有限公司 | 融合一代靶向cd7 car和二代靶向bcma的双靶点通用car-t细胞及制备方法 |
WO2024019961A1 (en) * | 2022-07-18 | 2024-01-25 | Cargo Therapeutics, Inc. | Cd2 recruiting chimeric antigen receptors and fusion proteins |
CN116284435A (zh) * | 2022-09-19 | 2023-06-23 | 卡瑞济(北京)生命科技有限公司 | EGFRvIII嵌合抗原受体及其用途 |
WO2024097797A1 (en) * | 2022-11-02 | 2024-05-10 | Medisix Therapeutics, Inc. | Blockade of cd3 expression and chimeric antigen receptors for immunotherapy |
CN116514992B (zh) * | 2022-11-07 | 2024-05-24 | 武汉波睿达生物科技有限公司 | 一种信号肽序列优化的靶向cd19的嵌合抗原受体及其应用 |
CN117866110B (zh) * | 2023-12-27 | 2024-06-11 | 广东唯泰生物科技有限公司 | 一种靶向flt-3的第四代嵌合抗原受体及其应用 |
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AU2002361390A1 (en) * | 2001-12-14 | 2003-06-30 | Friedrich-Alexander-Universitaet Erlangen-Nuernberg | Anti-cd7 immunotoxin as fusion protein |
US20130280220A1 (en) * | 2012-04-20 | 2013-10-24 | Nabil Ahmed | Chimeric antigen receptor for bispecific activation and targeting of t lymphocytes |
EP3215168B1 (de) * | 2014-10-31 | 2023-08-02 | The Trustees of the University of Pennsylvania | Änderung der genexpression in modifizierten t-zellen und verwendungen davon |
WO2017112877A1 (en) * | 2015-12-22 | 2017-06-29 | Icell Gene Therapeutics, Llc | Chimeric antigen receptors and enhancement of anti-tumor activity |
WO2018027036A1 (en) * | 2016-08-03 | 2018-02-08 | Dipersio John F | Gene editing of car-t cells for the treatment of t cell malignancies with chimeric antigen receptors |
US20200109364A1 (en) * | 2018-05-31 | 2020-04-09 | Washington University | Methods for genome-editing and activation of cells |
JP2021525530A (ja) * | 2018-06-01 | 2021-09-27 | ワシントン・ユニバーシティWashington University | キメラ抗原受容体細胞治療薬を用いたサイトカイン放出症候群の抑制 |
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WO2019232444A1 (en) | 2019-12-05 |
EP3802798A4 (de) | 2022-05-11 |
JP2021525524A (ja) | 2021-09-27 |
IL279063A (en) | 2021-01-31 |
CA3101505A1 (en) | 2019-12-05 |
JP7542854B2 (ja) | 2024-09-02 |
CN112912493A (zh) | 2021-06-04 |
EP3802798A1 (de) | 2021-04-14 |
AU2019279021A1 (en) | 2020-12-10 |
SG11202011383VA (en) | 2020-12-30 |
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