KR20210002140A - Feminine Cleanser Composition - Google Patents
Feminine Cleanser Composition Download PDFInfo
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- KR20210002140A KR20210002140A KR1020190075488A KR20190075488A KR20210002140A KR 20210002140 A KR20210002140 A KR 20210002140A KR 1020190075488 A KR1020190075488 A KR 1020190075488A KR 20190075488 A KR20190075488 A KR 20190075488A KR 20210002140 A KR20210002140 A KR 20210002140A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
Description
본 발명은 여성청결제 조성물에 관한 것이다.The present invention relates to a feminine cleansing composition.
여성의 질 내부는 미생물이 자라기 좋은 환경이며, 항문과 가깝기 때문에 청결에 신경 쓰지 않으면 세균에 노출되기 쉬어 여성 질환이 발생하기 쉽다. The inside of a woman's vagina is a good environment for microorganisms to grow, and because it is close to the anus, if you don't care about cleanliness, you are likely to be exposed to germs, and female diseases are likely to occur.
여성 질환으로 알려진 질염은 질분비물, 냄새, 작열감, 배뇨통 등의 증상을 호소하며, 세균성 질염(Bacterail Vagionosis), 칸디다 질염(Candida Vaginitis), 트리코모나스 질염(Trichomonas Vaginitis) 등으로 구분할 수 있고, 세균성 질염과 더불어 흔한 질환인 칸디다 질염은 진균인 Candida albicans 균에 의해 발병되어, 냉이 많아지거나 피부에 염증 반응으로 인한 가려움을 동반시킨다. Vaginitis, known as a female disease, complains of symptoms such as vaginal discharge, odor, burning sensation, and urinary pain. In addition, Candida vaginitis, a common disease, is caused by the fungus Candida albicans , causing increased coldness or itching due to an inflammatory reaction to the skin.
여성청결제는 여성 질환을 예방하기 위하여 여성의 외음부에 사용하는 전용 세정제로, 질 내에 유해 세균과 냄새를 잡아주고 적정 산도를 유지하여 질 분비물에서의 냄새를 없애거나 질염을 예방할 수 있게 한다. Feminine Cleanser is an exclusive cleanser used on the vulva of women to prevent female diseases. It catches harmful bacteria and odors in the vagina and maintains an appropriate acidity to remove odors from vaginal discharge or prevent vaginitis.
다만, 일반적인 여성청결제는 피부에 자극 및 손상을 주거나 알레르기 등을 유발할 수 있는 화학성분을 포함하고 있어 유해논란이 존재하며, 천연물질을 포함하는 여성청결제의 경우에도 특히 Candida albicans 균에 대한 우수한 억제 및 예방 효능을 가지도록 요구되고 있다. However, since general feminine cleansers contain chemicals that can irritate and damage the skin or cause allergies, there is a controversy, and even feminine cleansers containing natural substances have excellent inhibition and excellent inhibition of Candida albicans bacteria. It is required to have a preventive effect.
한국공개특허 제10-2005-0118819호는 천연물로 혼합된 세정제 조성물을 개시하고 있으나 화학합성계면활성제인 소디움라우릴셀페이트(SDS)를 사용하고 있어, 유해논란이 존재한다. Korean Patent Laid-Open Publication No. 10-2005-0118819 discloses a detergent composition mixed with natural substances, but it uses sodium lauryl sulfate (SDS), which is a chemically synthesized surfactant, and there is a harmful controversy.
이에, 본 발명자들은 상기 문제점을 해결하기 위해, 천연 추출물, 베타글루칸 및 락토바실러스를 포함하는 여성청결제 조성물을 제공하여, 상술한 문제점이 개선됨을 확인하고, 본 발명을 완성하게 되었다. Accordingly, in order to solve the above problems, the present inventors provided a feminine cleansing composition comprising a natural extract, beta glucan and lactobacilli, confirmed that the above-described problems were improved, and completed the present invention.
이에 본 발명에서는 친환경물질로 구성되는 여성청결제 조성물을 제공하여, 칸디다 질염을 유발하는 균을 억제하여 칸디다 질염을 예방하고자 한다. Accordingly, in the present invention, by providing a feminine cleansing composition composed of an eco-friendly material, it is intended to prevent Candida vaginitis by inhibiting the bacteria that cause Candida vaginitis.
상기 과제를 해결하기 위한 본 발명의 바람직한 일 구현예는 고삼, 단삼, 사상자, 지부자, 황금, 황련 및 황백을 포함하는 천연 추출물; 락토바실러스(Lactobacillus); 및 베타글루칸을 포함하는 여성청결제 조성물을 제공하는 것이다. A preferred embodiment of the present invention for solving the above problems is a natural extract containing gosam, dansam, casualty, branch, golden, yellow lotus and hwangbaek; Lactobacillus ; And it is to provide a feminine cleansing composition comprising beta-glucan.
상기 여성청결제 조성물은 베타글루칸과, 천연 추출물 및 락토바실러스의 혼합물의 중량비가 1:0.5 내지 1:8 인 것을 특징으로 할 수 있다. The feminine cleansing composition may be characterized in that the weight ratio of the mixture of beta glucan, natural extract and lactobacilli is 1:0.5 to 1:8.
상기 여성청결제 조성물은 천연 추출물 10g 당 락토바실러스가 1*105~1*106 CFU인 것을 특징으로 할 수 있다. The feminine cleansing composition may be characterized in that Lactobacillus per 10 g of natural extract is 1*10 5 ~1*10 6 CFU.
상기 락토바실러스는 락토바실러스 아시도필루스(Lactobacillus acidophilus)인 것을 특징으로 할 수 있다. The Lactobacillus may be characterized in that the Lactobacillus acidophilus ( Lactobacillus acidophilus ).
본 발명의 여성세정제 조성물은 화학성분을 대신 칸디다 질염에 대해 항균, 항진균, 살균 효과가 우수한 천연물질 및 균을 포함하여 칸디다 질염을 억제하거나 예방할 수 있다. The female cleansing composition of the present invention can suppress or prevent Candida vaginitis by including natural substances and bacteria having excellent antibacterial, antifungal, and bactericidal effects against Candida vaginitis instead of chemical components.
본 발명의 바람직한 일 구현예는 고삼, 단삼, 사상자, 지부자, 황금, 황련 및 황백을 포함하는 천연물에서 추출되는 추출물; 락토바실러스(Lactobacillus); 및 베타글루칸을 포함하는 여성청결제 조성물을 제공한다.A preferred embodiment of the present invention is an extract extracted from natural products including gosam, dansam, casualty, branch, golden, yellow lotus and hwangbaek; Lactobacillus ; And it provides a feminine cleansing composition comprising beta-glucan.
이하, 본 발명을 보다 구체적으로 설명한다. Hereinafter, the present invention will be described in more detail.
본 발명의 천연 추출물은 고삼, 단삼, 사상자, 지부자, 황금, 황련 및 황백을 포함하는 천연물에서 추출되는 추출물로서, 칸디다 질염을 유발하는 Candida albicans 균에 대해 우수한 항균효과를 가질 수 있다. The natural extract of the present invention is an extract extracted from natural products including Gosam, Dansam, Casualty, Jibuja, Golden, Hwangryeon and Hwangbaek, and may have an excellent antibacterial effect against Candida albicans bacteria that cause Candida vaginitis.
상기 고삼(Sophora flavescens AIT)은 해열작용과 이뇨작용 등의 약리 작용을 가지며, 살충제로 사용될 수 있는 것으로 보고되고 있다. The Sophora flavescens AIT has pharmacological effects such as antipyretic and diuretic, and it is reported that it can be used as an insecticide.
상기 단삼(Salvia miltiorrhiza BUNGE)은 포도상구균, 대장균, 티푸스균, 결햅균에 대해 항균작용을 하여, 월경통, 생리불순 및 산후의 하복부 통증이 심할 때에 사용될 수 있는 것으로 보고되고 있다.The Salvia miltiorrhiza BUNGE has an antibacterial action against Staphylococcus aureus, Escherichia coli, Typhoid bacteria, and Mycobacterium tuberculosis, and it is reported that it can be used when menstrual pain, dysmenorrhea and postpartum lower abdominal pain are severe.
상기 사상자는(Torilis japonica)는 수렴제, 소염제, 살충제로 사용될 수 있는 것을 보고되고 있다. The casualty (Torilis japonica) has been reported to be used as an astringent, anti-inflammatory, and insecticide.
상기 지부자(Kochia scoparia Schrader)는 간 보호 작용, 이뇨 작용, 해독 작용, 항균 작용 등의 약리 작용을 가지는 것으로 보고되고 있다. The Jibuja (Kochia scoparia Schrader) has been reported to have pharmacological effects such as liver protective action, diuretic action, detoxification action, and antibacterial action.
상기 황금(Scutellariae Radix)은 꿀풀과(Labiatae)에 속하는 다년생 초본인 속썩은풀(Scutellaria baicalensis Georgi)의 뿌리이며, 상기 황금의 뿌리는 baicalein, baicalin, wogonin, wogonoside, neobaicalein, benzoic acid, β-sitosterol 등의 성분을 함유되어 있다고 보고되었으며, 항균작용, 항미생물작용, 항염작용, 항변태반응, 해열 작용, 소염 작용, 이담 작용, 이뇨 작용 등의 약리 작용을 가지는 것으로 보고되고 있다. The gold (Scutellariae Radix) is the root of Scutellaria baicalensis Georgi, a perennial herb belonging to the Lamiaceae family (Labiatae), and the root of the gold is baicalein, baicalin, wogonin, wogonoside, neobaicalein, benzoic acid, β-sitosterol It has been reported that it contains components such as antibacterial, antimicrobial, anti-inflammatory, anti-metamorphic, antipyretic, anti-inflammatory, otorrhea, and diuretic.
상기 황련(Coptis chinensis)은 소화불량, 위염, 장염, 복통, 하혈, 코피, 번열 등을 치료하는데 사용되는 것으로 보고되고 있다. The Coptis chinensis is reported to be used to treat indigestion, gastritis, enteritis, abdominal pain, bleeding, nosebleeds, and fever.
상기 황백(Phellodendron amurense)은 폐렴쌍구균, 인형결핵균, 포도상구균 등에 대하여 발육저지 작용을 하며, 종양세포의 번식 저지 및 살균작용을 하는 것으로 보고되고 있다. The Hwangbaek (Phellodendron amurense) is reported to inhibit the growth of pneumococcal, tuberculosis pneumoniae, staphylococcus, etc., and inhibit the reproduction and sterilization of tumor cells.
상기 천연 추출물은 고삼, 단삼, 사상자, 지부자, 황금, 황련 및 황백을 포함하는 것이 상기 효과 측면에서 바람직하고, 특히 Candida albicans 균에 대한 항균, 항진균, 살균 작용 효과를 고양시키는 측면에서 고삼, 단삼, 사상자, 지부자, 황금, 황련 및 황백 이외의 천연물을 더 포함할 수 있다. The natural extracts include Gosam, Dansam, Casualty, Jibuja, Golden, Hwangryeon and Hwangbaek in the aspect of the above effect, and in particular, in terms of enhancing antibacterial, antifungal, and bactericidal effects against Candida albicans bacteria, Gosam, Dansam, It may further contain natural products other than casualties, branch people, gold, yellow lotus and yellow white.
상기 천연물은 물, 알코올 또는 이의 혼합물을 추출용매로 사용하여 추출할 수 있으며, 추출방법으로는 초음파추출, 진탕추출, Soxhlet 추출 또는 환류 추출을 이용하는 것이 바람직하나 이에 한정되지 않는다. The natural product may be extracted using water, alcohol, or a mixture thereof as an extraction solvent, and the extraction method is preferably ultrasonic extraction, shaking extraction, Soxhlet extraction, or reflux extraction, but is not limited thereto.
본 발명의 락토바실러스(Lactobacillus)는 락토바실러스 플란타룸(Lactobacillus plantarum), 락토바실러스 아시도필루스(Lactobacillus acidophilus), 락토바실러스 카제이(Lactobacillus casei)의 락토바실러스 균을 포함할 수 있고, 락토바실러스 아시도필루스(Lactobacillus acidophilus)인 것이 질염에 의해 감소되는 유산균을 증진시키는 점에서 바람직하다. Lactobacillus ( Lactobacillus ) of the present invention may contain Lactobacillus bacteria of Lactobacillus plantarum ( Lactobacillus plantarum ), Lactobacillus acidophilus ( Lactobacillus acidophilus ), Lactobacillus casei ( Lactobacillus casei ), Lactobacillus Acidophilus ( Lactobacillus acidophilus ) is preferred in terms of promoting lactic acid bacteria that are reduced by vaginitis.
상기 락토바실러스는 천연 추출물 10g 당 락토바실러스가 1*105~1*106 CFU인 것이 바람직하다. The Lactobacillus is preferably 1*10 5 ~ 1*10 6 CFU of Lactobacillus per 10 g of natural extract.
본 발명의 베타글루칸은 세균 예방 및 질내 면역력을 강화할 수 있다. The beta-glucan of the present invention can prevent bacteria and strengthen vaginal immunity.
상기 베타글루칸은 칸디다 질염을 유발하는 Candida albicans 균에 대한 우수한 항균, 항진균 효과를 가질 수 있다. 상기 베타글루칸은 상기 천연 추출물 및 락토바실러스(Lactobacillus)를 혼합한 혼합물과의 중량비가 1:0.5 내지 1:8일 때, 항균, 항진균 성능이 우수해질 수 있다. The beta-glucan may have excellent antibacterial and antifungal effects against Candida albicans bacteria that cause Candida vaginitis. The beta-glucan is the weight ratio of the mixture and a mixture of the natural extracts and Lactobacillus bacteria (Lactobacillus) 1: 0.5 to 1: A, can be excellent in antibacterial, antifungal performance when eight days.
본 발명의 일 구현예로 제공된 여성청결제 조성물은 비누, 세정제 용품으로 사용되어, 칸디다 균에 대해 우수한 항균, 항진균 효과를 가지는 여성청결제로 사용될 수 있고, 본 발명의 추출물, 락토바실러스 및 베타글구칸 이외의 다른 공지 항균 물질을 더 포함할 수 있다. The feminine cleansing composition provided as an embodiment of the present invention can be used as a soap, a cleansing product, and can be used as a feminine cleansing agent having excellent antibacterial and antifungal effects against Candida bacteria. It may further include other known antibacterial substances.
Claims (4)
The female cleansing composition according to claim 1, wherein the Lactobacillus is Lactobacillus acidophilus .
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