KR20200143399A - 중간엽 줄기 세포의 창상 치유 특성을 유도 또는 개선시키는 방법 - Google Patents
중간엽 줄기 세포의 창상 치유 특성을 유도 또는 개선시키는 방법 Download PDFInfo
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- KR20200143399A KR20200143399A KR1020207030469A KR20207030469A KR20200143399A KR 20200143399 A KR20200143399 A KR 20200143399A KR 1020207030469 A KR1020207030469 A KR 1020207030469A KR 20207030469 A KR20207030469 A KR 20207030469A KR 20200143399 A KR20200143399 A KR 20200143399A
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- mesenchymal stem
- stem cell
- cell population
- cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/395—Thyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
- C12N2509/10—Mechanical dissociation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862656531P | 2018-04-12 | 2018-04-12 | |
| US62/656,531 | 2018-04-12 | ||
| PCT/SG2019/050204 WO2019199234A1 (en) | 2018-04-12 | 2019-04-12 | A method of inducing or improving wound healing properties of mesenchymal stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20200143399A true KR20200143399A (ko) | 2020-12-23 |
Family
ID=68163253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207030469A Ceased KR20200143399A (ko) | 2018-04-12 | 2019-04-12 | 중간엽 줄기 세포의 창상 치유 특성을 유도 또는 개선시키는 방법 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3775163A4 (https=) |
| JP (2) | JP7541730B2 (https=) |
| KR (1) | KR20200143399A (https=) |
| CN (2) | CN120608017A (https=) |
| AU (1) | AU2019250653B2 (https=) |
| BR (1) | BR112020020092A2 (https=) |
| CA (1) | CA3095490A1 (https=) |
| PH (1) | PH12020551658A1 (https=) |
| SG (1) | SG11202009687PA (https=) |
| TW (1) | TWI882956B (https=) |
| WO (1) | WO2019199234A1 (https=) |
| ZA (1) | ZA202005967B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020362379A1 (en) | 2019-10-08 | 2022-04-07 | Cellresearch Corporation Pte. Ltd. | A method of assessing wound healing potency of a mesenchymal stem population and related methods of selecting mesenchymal stem cells and identifying tissue as starting material for producing a mesenchymal stem cell population |
| WO2021071430A1 (en) * | 2019-10-08 | 2021-04-15 | Cellresearch Corporation Pte. Ltd. | A mesenchymal stem cell storing or transport formulation and methods of making and using the same |
| WO2021257073A1 (en) * | 2020-06-17 | 2021-12-23 | Joy Kong | Method for producing mesenchymal stem cells from neonatal stem cells |
| WO2022004938A1 (ko) * | 2020-06-30 | 2022-01-06 | 주식회사 미래셀바이오 | 유사 중간엽 줄기세포의 제조방법 |
| CN114196626A (zh) * | 2022-02-16 | 2022-03-18 | 北京国卫生物科技有限公司 | 脐带间充质干细胞及其分离培养扩增方法 |
| WO2024107102A1 (en) * | 2022-11-17 | 2024-05-23 | Cellresearch Corporation Pte. Ltd. | Use of conditioned medium derived from cultivation of mesenchymal stem cells of the umbilical cord for inducing, stimulating and promoting hair growth and regeneration |
| WO2024123237A1 (en) * | 2022-12-09 | 2024-06-13 | Cellresearch Corporation Pte. Ltd. | Use of conditioned medium of cord lining mesenchymal stem cells for healing and/or preventing the formation and/or recurrence of a wound or a damaged skin area |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1288293A1 (en) | 2001-08-30 | 2003-03-05 | Norio Sakuragawa | Human neural stem cells originated from human amniotic mesenchymal cell layer |
| WO2004072273A1 (en) | 2003-02-11 | 2004-08-26 | Davies John E | Progenitor cells from wharton's jelly of human umbilical cord |
| TWI287010B (en) * | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
| PL1789534T3 (pl) | 2004-08-16 | 2015-03-31 | Cellresearch Corp Pte Ltd | Wyodrębnienie komórek macierzystych/progenitorowych z błony owodniowej pępowiny |
| CN101189341B (zh) * | 2005-04-04 | 2016-10-19 | 纳幕尔杜邦公司 | 用于制备抗真菌病原体的植物的多核苷酸和方法 |
| CN103555655B (zh) * | 2005-10-21 | 2018-02-27 | 细胞研究私人有限公司 | 自脐带羊膜分离和培养干/祖细胞及其分化的细胞的应用 |
| WO2007121263A2 (en) * | 2006-04-14 | 2007-10-25 | Wako Pure Chemical Industries, Ltd | Structure for introducing a plurality of solutions, micro fluidic device having said structure and method for introducing solution |
| US20100136681A1 (en) * | 2007-04-02 | 2010-06-03 | The General Hospital Corporation | Cellular compositions for the treatment of kidney disease and uses thereof |
| KR101138091B1 (ko) * | 2011-08-31 | 2012-04-24 | 세원셀론텍(주) | 중간엽 줄기세포 기본 배양 배지 조성방법, 중간엽 줄기세포 기본 배양 배지 및 이를 이용하여 배양분화된 세포치료제 |
| WO2013059528A2 (en) * | 2011-10-18 | 2013-04-25 | City Of Hope | Encapsulated diagnostics and therapeutics in nanoparticles-conjugated to tropic cells and methods for their use |
| US9670488B2 (en) * | 2011-11-04 | 2017-06-06 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of met by double stranded RNA |
| CN103301154B (zh) * | 2013-04-19 | 2014-12-17 | 胡祥 | 脐带间充质干细胞在制备治疗红斑狼疮的制剂中的用途 |
| CN104630142B (zh) * | 2015-02-06 | 2018-06-05 | 广州赛莱拉干细胞科技股份有限公司 | 一种牛脐带间充质干细胞的分离及培养方法 |
| KR102676761B1 (ko) * | 2015-12-03 | 2024-06-18 | 다카라 바이오 가부시키가이샤 | 중간엽 줄기세포의 제조방법 |
| WO2017096607A1 (zh) | 2015-12-11 | 2017-06-15 | 郭镭 | 一种从脐带外层羊膜组织中分离提取hUC-MSC的方法 |
| CN105420179A (zh) * | 2015-12-17 | 2016-03-23 | 斯坦姆(天津)生物技术研究有限公司 | 一种从脐带和胎盘羊膜组织同时提取上皮细胞和间充质干细胞的方法 |
| CN106119191A (zh) * | 2016-07-05 | 2016-11-16 | 四川华皓生物科技有限公司 | 一种胎盘绒毛板间充质干细胞及临床化制备方法 |
| CN106377544A (zh) * | 2016-09-30 | 2017-02-08 | 广州赛莱拉干细胞科技股份有限公司 | 脐带间充质干细胞上清液在制备治疗口腔溃疡药物中的应用及漱口液和其制备方法 |
| PL3523421T3 (pl) | 2016-10-05 | 2025-06-09 | Cellresearch Corporation Pte. Ltd. | Sposób izolowania mezenchymalnych komórek macierzystych z błony owodniowej pępowiny przy użyciu podłoża do hodowli komórkowej |
| WO2019199230A1 (en) | 2018-04-09 | 2019-10-17 | Cellresearch Corporation Pte. Ltd. | A method of transporting mesenchymal stem cells by means of a cell culture medium and a method of administering stem cells to wounds |
-
2019
- 2019-04-11 TW TW108112754A patent/TWI882956B/zh active
- 2019-04-12 WO PCT/SG2019/050204 patent/WO2019199234A1/en not_active Ceased
- 2019-04-12 EP EP19784508.4A patent/EP3775163A4/en active Pending
- 2019-04-12 BR BR112020020092-1A patent/BR112020020092A2/pt unknown
- 2019-04-12 CN CN202510513409.1A patent/CN120608017A/zh active Pending
- 2019-04-12 CA CA3095490A patent/CA3095490A1/en active Pending
- 2019-04-12 JP JP2020555404A patent/JP7541730B2/ja active Active
- 2019-04-12 SG SG11202009687PA patent/SG11202009687PA/en unknown
- 2019-04-12 KR KR1020207030469A patent/KR20200143399A/ko not_active Ceased
- 2019-04-12 AU AU2019250653A patent/AU2019250653B2/en active Active
- 2019-04-12 CN CN201980039206.6A patent/CN112262211B/zh active Active
-
2020
- 2020-09-28 ZA ZA2020/05967A patent/ZA202005967B/en unknown
- 2020-10-07 PH PH12020551658A patent/PH12020551658A1/en unknown
-
2024
- 2024-03-08 JP JP2024035680A patent/JP2024069365A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024069365A (ja) | 2024-05-21 |
| JP2021526125A (ja) | 2021-09-30 |
| SG11202009687PA (en) | 2020-10-29 |
| CN120608017A (zh) | 2025-09-09 |
| ZA202005967B (en) | 2021-08-25 |
| JP7541730B2 (ja) | 2024-08-29 |
| EP3775163A4 (en) | 2022-03-09 |
| AU2019250653A1 (en) | 2020-10-15 |
| PH12020551658A1 (en) | 2021-07-26 |
| EP3775163A1 (en) | 2021-02-17 |
| TW202012618A (zh) | 2020-04-01 |
| TWI882956B (zh) | 2025-05-11 |
| CN112262211B (zh) | 2025-05-09 |
| BR112020020092A2 (pt) | 2021-02-17 |
| CN112262211A (zh) | 2021-01-22 |
| AU2019250653B2 (en) | 2025-06-19 |
| CA3095490A1 (en) | 2019-10-17 |
| WO2019199234A1 (en) | 2019-10-17 |
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| P11 | Amendment of application requested |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |