JP7541730B2 - 間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 - Google Patents
間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 Download PDFInfo
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- JP7541730B2 JP7541730B2 JP2020555404A JP2020555404A JP7541730B2 JP 7541730 B2 JP7541730 B2 JP 7541730B2 JP 2020555404 A JP2020555404 A JP 2020555404A JP 2020555404 A JP2020555404 A JP 2020555404A JP 7541730 B2 JP7541730 B2 JP 7541730B2
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- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/395—Thyroid hormones
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- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
- C12N2509/10—Mechanical dissociation
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024035680A JP2024069365A (ja) | 2018-04-12 | 2024-03-08 | 間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862656531P | 2018-04-12 | 2018-04-12 | |
| US62/656,531 | 2018-04-12 | ||
| PCT/SG2019/050204 WO2019199234A1 (en) | 2018-04-12 | 2019-04-12 | A method of inducing or improving wound healing properties of mesenchymal stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024035680A Division JP2024069365A (ja) | 2018-04-12 | 2024-03-08 | 間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021526125A JP2021526125A (ja) | 2021-09-30 |
| JP2021526125A5 JP2021526125A5 (https=) | 2022-04-19 |
| JP7541730B2 true JP7541730B2 (ja) | 2024-08-29 |
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ID=68163253
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020555404A Active JP7541730B2 (ja) | 2018-04-12 | 2019-04-12 | 間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 |
| JP2024035680A Pending JP2024069365A (ja) | 2018-04-12 | 2024-03-08 | 間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024035680A Pending JP2024069365A (ja) | 2018-04-12 | 2024-03-08 | 間葉系幹細胞の創傷治癒特性を誘導するまたは改善する方法 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3775163A4 (https=) |
| JP (2) | JP7541730B2 (https=) |
| KR (1) | KR20200143399A (https=) |
| CN (2) | CN120608017A (https=) |
| AU (1) | AU2019250653B2 (https=) |
| BR (1) | BR112020020092A2 (https=) |
| CA (1) | CA3095490A1 (https=) |
| PH (1) | PH12020551658A1 (https=) |
| SG (1) | SG11202009687PA (https=) |
| TW (1) | TWI882956B (https=) |
| WO (1) | WO2019199234A1 (https=) |
| ZA (1) | ZA202005967B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020362379A1 (en) | 2019-10-08 | 2022-04-07 | Cellresearch Corporation Pte. Ltd. | A method of assessing wound healing potency of a mesenchymal stem population and related methods of selecting mesenchymal stem cells and identifying tissue as starting material for producing a mesenchymal stem cell population |
| WO2021071430A1 (en) * | 2019-10-08 | 2021-04-15 | Cellresearch Corporation Pte. Ltd. | A mesenchymal stem cell storing or transport formulation and methods of making and using the same |
| WO2021257073A1 (en) * | 2020-06-17 | 2021-12-23 | Joy Kong | Method for producing mesenchymal stem cells from neonatal stem cells |
| WO2022004938A1 (ko) * | 2020-06-30 | 2022-01-06 | 주식회사 미래셀바이오 | 유사 중간엽 줄기세포의 제조방법 |
| CN114196626A (zh) * | 2022-02-16 | 2022-03-18 | 北京国卫生物科技有限公司 | 脐带间充质干细胞及其分离培养扩增方法 |
| WO2024107102A1 (en) * | 2022-11-17 | 2024-05-23 | Cellresearch Corporation Pte. Ltd. | Use of conditioned medium derived from cultivation of mesenchymal stem cells of the umbilical cord for inducing, stimulating and promoting hair growth and regeneration |
| WO2024123237A1 (en) * | 2022-12-09 | 2024-06-13 | Cellresearch Corporation Pte. Ltd. | Use of conditioned medium of cord lining mesenchymal stem cells for healing and/or preventing the formation and/or recurrence of a wound or a damaged skin area |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007046775A1 (en) | 2005-10-21 | 2007-04-26 | Cellresearch Corporation Pte Ltd | Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of cells differentiated therefrom |
| JP2014525262A (ja) | 2011-08-31 | 2014-09-29 | セウォン セロンテック カンパニー リミテッド | 間葉系幹細胞の基本培養培地の調製方法、間葉系幹細胞の基本培養培地及びこれを利用して培養分化した細胞治療剤 |
| WO2017094879A1 (ja) | 2015-12-03 | 2017-06-08 | タカラバイオ株式会社 | 間葉系幹細胞の製造方法 |
| JP2019530448A (ja) | 2016-10-05 | 2019-10-24 | セルリサーチ コーポレイション プロプライエタリー リミテッド | 細胞培養液を用いて臍帯羊膜から間葉系幹細胞を単離する方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1288293A1 (en) | 2001-08-30 | 2003-03-05 | Norio Sakuragawa | Human neural stem cells originated from human amniotic mesenchymal cell layer |
| WO2004072273A1 (en) | 2003-02-11 | 2004-08-26 | Davies John E | Progenitor cells from wharton's jelly of human umbilical cord |
| TWI287010B (en) * | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
| PL1789534T3 (pl) | 2004-08-16 | 2015-03-31 | Cellresearch Corp Pte Ltd | Wyodrębnienie komórek macierzystych/progenitorowych z błony owodniowej pępowiny |
| CN101189341B (zh) * | 2005-04-04 | 2016-10-19 | 纳幕尔杜邦公司 | 用于制备抗真菌病原体的植物的多核苷酸和方法 |
| WO2007121263A2 (en) * | 2006-04-14 | 2007-10-25 | Wako Pure Chemical Industries, Ltd | Structure for introducing a plurality of solutions, micro fluidic device having said structure and method for introducing solution |
| US20100136681A1 (en) * | 2007-04-02 | 2010-06-03 | The General Hospital Corporation | Cellular compositions for the treatment of kidney disease and uses thereof |
| WO2013059528A2 (en) * | 2011-10-18 | 2013-04-25 | City Of Hope | Encapsulated diagnostics and therapeutics in nanoparticles-conjugated to tropic cells and methods for their use |
| US9670488B2 (en) * | 2011-11-04 | 2017-06-06 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of met by double stranded RNA |
| CN103301154B (zh) * | 2013-04-19 | 2014-12-17 | 胡祥 | 脐带间充质干细胞在制备治疗红斑狼疮的制剂中的用途 |
| CN104630142B (zh) * | 2015-02-06 | 2018-06-05 | 广州赛莱拉干细胞科技股份有限公司 | 一种牛脐带间充质干细胞的分离及培养方法 |
| WO2017096607A1 (zh) | 2015-12-11 | 2017-06-15 | 郭镭 | 一种从脐带外层羊膜组织中分离提取hUC-MSC的方法 |
| CN105420179A (zh) * | 2015-12-17 | 2016-03-23 | 斯坦姆(天津)生物技术研究有限公司 | 一种从脐带和胎盘羊膜组织同时提取上皮细胞和间充质干细胞的方法 |
| CN106119191A (zh) * | 2016-07-05 | 2016-11-16 | 四川华皓生物科技有限公司 | 一种胎盘绒毛板间充质干细胞及临床化制备方法 |
| CN106377544A (zh) * | 2016-09-30 | 2017-02-08 | 广州赛莱拉干细胞科技股份有限公司 | 脐带间充质干细胞上清液在制备治疗口腔溃疡药物中的应用及漱口液和其制备方法 |
| WO2019199230A1 (en) | 2018-04-09 | 2019-10-17 | Cellresearch Corporation Pte. Ltd. | A method of transporting mesenchymal stem cells by means of a cell culture medium and a method of administering stem cells to wounds |
-
2019
- 2019-04-11 TW TW108112754A patent/TWI882956B/zh active
- 2019-04-12 WO PCT/SG2019/050204 patent/WO2019199234A1/en not_active Ceased
- 2019-04-12 EP EP19784508.4A patent/EP3775163A4/en active Pending
- 2019-04-12 BR BR112020020092-1A patent/BR112020020092A2/pt unknown
- 2019-04-12 CN CN202510513409.1A patent/CN120608017A/zh active Pending
- 2019-04-12 CA CA3095490A patent/CA3095490A1/en active Pending
- 2019-04-12 JP JP2020555404A patent/JP7541730B2/ja active Active
- 2019-04-12 SG SG11202009687PA patent/SG11202009687PA/en unknown
- 2019-04-12 KR KR1020207030469A patent/KR20200143399A/ko not_active Ceased
- 2019-04-12 AU AU2019250653A patent/AU2019250653B2/en active Active
- 2019-04-12 CN CN201980039206.6A patent/CN112262211B/zh active Active
-
2020
- 2020-09-28 ZA ZA2020/05967A patent/ZA202005967B/en unknown
- 2020-10-07 PH PH12020551658A patent/PH12020551658A1/en unknown
-
2024
- 2024-03-08 JP JP2024035680A patent/JP2024069365A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007046775A1 (en) | 2005-10-21 | 2007-04-26 | Cellresearch Corporation Pte Ltd | Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of cells differentiated therefrom |
| JP2014525262A (ja) | 2011-08-31 | 2014-09-29 | セウォン セロンテック カンパニー リミテッド | 間葉系幹細胞の基本培養培地の調製方法、間葉系幹細胞の基本培養培地及びこれを利用して培養分化した細胞治療剤 |
| WO2017094879A1 (ja) | 2015-12-03 | 2017-06-08 | タカラバイオ株式会社 | 間葉系幹細胞の製造方法 |
| JP2019530448A (ja) | 2016-10-05 | 2019-10-24 | セルリサーチ コーポレイション プロプライエタリー リミテッド | 細胞培養液を用いて臍帯羊膜から間葉系幹細胞を単離する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024069365A (ja) | 2024-05-21 |
| JP2021526125A (ja) | 2021-09-30 |
| SG11202009687PA (en) | 2020-10-29 |
| CN120608017A (zh) | 2025-09-09 |
| ZA202005967B (en) | 2021-08-25 |
| EP3775163A4 (en) | 2022-03-09 |
| AU2019250653A1 (en) | 2020-10-15 |
| PH12020551658A1 (en) | 2021-07-26 |
| EP3775163A1 (en) | 2021-02-17 |
| KR20200143399A (ko) | 2020-12-23 |
| TW202012618A (zh) | 2020-04-01 |
| TWI882956B (zh) | 2025-05-11 |
| CN112262211B (zh) | 2025-05-09 |
| BR112020020092A2 (pt) | 2021-02-17 |
| CN112262211A (zh) | 2021-01-22 |
| AU2019250653B2 (en) | 2025-06-19 |
| CA3095490A1 (en) | 2019-10-17 |
| WO2019199234A1 (en) | 2019-10-17 |
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