KR20200034570A - Composition for Removing Halitosis - Google Patents

Abstract

The present invention relates to a composition for removing bad breath containing plant extracts such as rosemary, etc. Plant extracts, such as rosemary, etc., are natural-derived active components which have no problem to human body safety, and have excellent ability to immediately remove a sulfur compound, which is a major component of bad breath. In addition, plant extracts exhibit a synergistic effect with alcohols having a molecular weight of 65 to 110, so that an effect of removing bad breath can be further improved.

Description

Composition for removing halitosis

The present invention relates to a bad breath removing composition having an excellent effect of removing bad smell, especially garlic / kimchi.

Bad breath is derived from the components of volatile sulfur compounds that are normally produced by the metabolism of microorganisms in the oral cavity. Koreans frequently consume foods containing garlic and onions, and fermented foods such as kimchi, and as a result, they have a unique bad breath in addition to bad breath derived from common microbial metabolites. Bad breath after ingestion of garlic, onion, and kimchi is mainly known as sulfur compounds derived from allicin (J. Agric. Food Chem. 1995, 43, 1751-1753; J. Agric. Food Chem., 1961, 9, 140-143; J. Agric. Food Chem. 1998, 46, 19441953).

As a method for suppressing such bad breath, a composition for promoting oral hygiene containing naxosol, which is extracted from and separated from Curcuma xanthorrhiza, is known. It uses antibacterial properties. In addition, a composition for enhancing oral hygiene using a bad breath-inducing substance removal characteristic of a copper compound centered on copper gluconate is known. However, these oral hygiene-promoting compositions not only focused on a fragmentary halitosis suppression system that eliminates the one-dimensional phosphorus of halitosis or eliminates halitosis-generating substances, but also have limitations in their effectiveness.

In addition, although a technique using herbal extracts to remove bad breath has been developed, it is insufficient to immediately remove Korean bad breath.

Numerous references are cited and cited throughout this specification. The disclosure content of the cited documents is incorporated by reference herein in its entirety and the level of the technical field to which the present invention pertains and the content of the present invention are more clearly described.

Republic of Korea Patent Publication No. 10-2000-0000256

The present inventors tried to provide a composition for removing bad breath, particularly a bad smell of garlic / kimchi, which is unique to Koreans. As a result, the present invention was completed by finding out that the effect is more excellent when an alcohol having a molecular weight of 65 to 110 is mixed with the plant extract.

Therefore, an object of the present invention is to provide a composition for removing bad breath excellent in the bad breath removal effect.

Another object of the present invention is to provide an oral product comprising the composition for removing bad breath.

Other objects and advantages of the present invention will become more apparent from the following detailed description of the invention, claims and drawings.

One aspect of the present invention is to provide a composition for removing bad breath comprising a plant extract.

The plant may be at least one selected from rosemary, celestial, Angelica, cinnamon, green tea, celery, eucalyptus, calendula, chamomile, lemon balm, Curcima xanthorrhiza and chlorophyll, preferably rosemary , Cinnamon, green tea, chamomile, lemon balm, and one or more selected from eucalyptus, most preferably rosemary extract may be used.

Rosemary (Rosmarinusofficinalis), which can be used as an active ingredient in the composition of the present invention, is an evergreen tree native to the Mediterranean belonging to the family Lamiaceae, and is one of the traditional European spices grown mainly in southern Europe. 1,8- It contains essential oils such as cineol (1,8-cineole), camphor, etc., and essential ingredients such as rosmarinic acid, so it has been medicated as a dry stomach, cartilage, anti-inflammatory and insecticide.

Cnidium officinale is a perennial herbaceous plant belonging to the apiaceae family of Ippanhwa-gun of the dicotyledon family. Young shoots are eaten as herbs, and the rootstock is dried to be used as a medicine, and contains a large amount of essential oil essential oils.

Angelica gigas is traditionally used as a herbal medicine in Asian countries, and is well known in the United States and Europe as a herbal medicine for women's health care. A coumarine-based compound is known as a herbal physiologically active ingredient of native Angelica native to Korea.

Cinnamon is a spice from some of the bark of the camphor tree (Cinnamomum). It is mainly used as a seasoning or spice, and is also used as a herbal medicine to treat anorexia, indigestion, colds, headaches, fever, nervous palpitations, and pain relief.

Green tea is made by inactivating polyphenoloxidase, an enzyme involved in the oxidation of tea leaves, by using the leaves of the camellia sinussis by heat treatment. Unlike green tea or oolong tea, it has a green color, search, and fresh flavor. It is characteristic. Green tea is known to have an anti-hypertensive effect, a cholesterol removal effect and an antibacterial antiviral effect.

Celery (Apium graveolens) is a plant species belonging to the family Apiaceae, and has small leaves of four to four centimeters, 3 to 6 cm long and 2 to 4 cm wide. The flower has a soft white color and is 2-3 millimeters in diameter. It is produced in a lush compound form, and is widely used as an edible plant in the world.

Eucalyptus is a genus of genus seeds belonging to the genus Pleuroaceae of the native subtropical highlands, consisting of shrubs and shrubs. Essential oils have a strong antiseptic action and are known to be effective in purifying the skin and improving skin disorders when used as a bathing agent. Eucalyptus is also effective in improving mental and stress, and has been used since ancient Egypt because it has the effect of maintaining young skin.

The calendula is an annual plant of the Chrysanthemum family, 30 ~ 50cm high, the leaves are misaligned, and have a peculiar smell. Calendula, also called marigold, is known to have the effect of promoting the regeneration of cells and preventing infection of bacteria and fungi.

Chamomile is a plant belonging to the family Asteraceae, and is also called chamomile, or kamille, chamomile. It is widely used as herbal tea, and since ancient times, chamomile has been used to relieve intestinal gas, headache, insomnia, low back pain, neuralgia, rheumatism, skin disease, indigestion and gout disease.

Lemon balm (Melissa officinalis) is a plant belonging to the family Lamitae, a perennial plant with cold-resistant perennials that grow to a height of about 60 to 150 cm. The stems are square, and the length of the leaves meets a broad ovate of about 8 cm. Lemon balm is known to contain a variety of active flavonoids.

Curcima xanthorrhiza is a plant species belonging to the ginger family, and grows and thrives in tropical climates up to 1500 meters above sea level, and its roots grow well in loose soil. Curcuma Zantoriza is used as a medicinal plant, and roots and stems are known to contain ether oil.

Chlorophyll (chlorophyll) is a green pigment contained in plants and is a key molecule in photosynthesis, a pigment that acts as an antenna that absorbs light energy.

The composition of the present invention contains a plant extract as an active ingredient. As used herein, the term 'extract' means not only an extract obtained by treating an extractant with a plant, but also a plant processed product that is formulated (eg, powdered) so that the plant itself can be applied to animals including humans. Have

When a plant extract containing rosemary or the like used in the composition of the present invention is obtained by treating an extractant with a plant containing rosemary or the like, various extraction solvents may be used, such as water, alcohol, acetic acid, alkyl ester, and ketone. , Alkanes, cycloalkanes, ethers, benzene, alkyl sulfides, chloroform and carbon tetrachloride.

More specifically, a polar solvent or a non-polar solvent can be used as the extraction solvent. Polar solvents are, for example, (i) water, (ii) alcohols (eg methanol, ethanol, propanol, butanol, normal-propanol, iso-propanol, normal-butanol, 1-pentanol, 2-butoxyethanol, ethylene glycol , Propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, dipropylene glycol) (iii) acetic acid, (iv) dimethyl-formamide (DMFO) and (v) dimethyl sulfoxide ). Non-polar solvents are, for example, acetone, acetonitrile, ethyl acetate, methyl acetate, fluoroalkane, pentane, hexane, 2,2,4-trimethylpentane, decane, cyclohexane, cyclopentane, diisobutylene, 1-pentene , 1-chlorobutane, 1-chloropentane, o-xylene, diisopropyl ether, 2-chloropropane, toluene, 1-chloropropane, chlorobenzene, benzene, diethyl ether, diethyl sulfide, chloroform, dichloromethane , 1,2-dichloroethane, anneal, diethylamine, ether, carbon tetrachloride, THF, isopropyl myristate. Plant extracts containing rosemary and the like used in the present invention include water, ethanol, 1,3-butylene glycol, propylene glycol, ethylene glycol, dipropylene glycol, hexylene glycol, and isopropylene It may also be obtained by treating a plant including rosemary or the like with a gly or a combination thereof.

The term 'extract' used in the present specification has a meaning commonly used as a crude extract in the art as described above, but broadly also includes a fraction in which an extract is additionally fractionated. That is, plant extracts such as rosemary are obtained not only using the above-described extraction solvent, but also those obtained by additionally applying a purification process. For example, a fraction obtained by passing the extract through an ultrafiltration membrane having a constant molecular weight cut-off value, separation by various chromatography (made for separation according to size, charge, hydrophobicity or affinity), etc. Fractions obtained through the purification method are also included in plant extracts such as rosemary of the present invention.

Plant extracts such as rosemary of the present invention as described above may contain polyphenols, and the polyphenol content may range from 10 to 10,000 mg gallic acid equivalent / 100 mL purified water.

In addition, plant extracts such as rosemary used in the present invention may be prepared in powder form by additional processes such as distillation under reduced pressure and freeze drying or spray drying.

In one embodiment of the present invention, the composition for removing bad breath is added to the above-mentioned plant extracts such as rosemary, alcohols having a molecular weight of 65 to 110, such as propylene glycol (molecular weight 76.09), butylene glycol (molecular weight 90.12) ), Butanol (molecular weight 74.1) isobutyl alcohol (molecular weight 74.1), pentanol (pentanol, molecular weight 88.15), isopentyl alcohol (molecular weight 88.15), hexanol (hexanol, molecular weight 102.17), 4 -Methyl-1-pentanol (4-methyl-1-pentanol, molecular weight 102.17) and pentylene glycol (pentylene glycol, molecular weight 104.15) may further include one or more selected from.

Alcohol having a molecular weight of 65 to 110 is different from that used as a simple extraction solvent for plant extracts such as rosemary. For example, the composition for removing bad breath of the present invention has a water extract and a molecular weight of 65 or less using plants such as rosemary. 110 may further include alcohol, wherein the alcohol is not a plant extractant.

The alcohol having a molecular weight of 65 to 110 may be included in the total composition in an amount of at least 0.0001% by weight, preferably 0.001 to 10% by weight, and more preferably 0.001 to 1% by weight.

In another embodiment of the present invention, plant extracts such as rosemary, which is an active ingredient of the composition for removing bad breath, may be an extract extracted with alcohol having a molecular weight of 65 to 110. In this case, the alcohol having a molecular weight of 65 to 110 is used as an extraction solvent for plant extracts such as rosemary.

In one aspect of the present invention, the composition may be a pharmaceutical composition for preventing or treating bad breath. In this case, the composition for removing bad breath may include one or more pharmaceutically acceptable carriers, excipients, or diluents, along with an effective amount of plant extracts such as rosemary.

The effective amount refers to an amount sufficient to prevent, ameliorate and treat the disease. This can be appropriately changed according to the severity of the disease, the patient's age, weight, health status, sex, route of administration, and treatment period.

In addition, “pharmaceutically acceptable” as used above refers to a composition that is physiologically acceptable and does not generally cause an allergic reaction such as gastrointestinal disorder, dizziness or similar reaction when administered to humans.

Examples of the carrier, excipients and diluents include lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol, starch, acacia rubber, alginate, gelatin, calcium phosphate, calcium silicate, cellulose, methyl cellulose, Polyvinylpyrrolidone, water, methylhydroxybenzoate, propyl hydroxybenzoate, talc, magnesium stearate and mineral oil. In addition, fillers, anti-coagulants, lubricants, wetting agents, fragrances, emulsifiers and preservatives may be further included.

In addition, the deodorant pharmaceutical composition can be formulated using methods known in the art to provide rapid, sustained or delayed release of the active ingredient after administration to a mammal. Formulations may be in the form of powders, granules, tablets, emulsions, syrups, aerosols, soft or hard gelatin capsules, sterile injectable solutions, sterile powders. In addition, the composition of the present invention may be administered in parallel with a known compound having an effect of preventing, improving or treating oral disease or bad breath.

As another aspect of the present invention, the composition may be a quasi-drug composition for preventing, improving or eliminating bad breath. When using a plant extract such as rosemary of the present invention as a quasi-drug additive, the active ingredient of the extract having bad breath removal activity can be added as it is or used with other quasi-drug or quasi-drug components, and can be suitably used according to a conventional method. . The mixing amount of the active ingredient can be appropriately determined according to the intended use.

The quasi-drug composition for removing bad breath of the present invention is not particularly limited in its formulation, and can be variously formulated in the form of quasi-drugs known in the art having a bad breath removal effect.

In addition, in each formulation, a quasi-drug composition for preventing, improving or removing bad breath may be arbitrarily selected and blended with other ingredients according to the formulation or purpose of use. For example, thickeners, stabilizers, solubilizers, vitamins, pigments, and conventional auxiliaries such as fragrances, and carriers may be included. The composition for quasi-drugs containing plant extracts such as rosemary of the present invention as an active ingredient itself is derived from plants and has little toxicity and side effects and can be safely used as a quasi-drug material.

As another aspect of the present invention, the composition may be a cosmetic composition for preventing, improving or removing bad breath.

The cosmetic composition for removing bad breath of the present invention may be variously formulated in the form of cosmetics known in the art, and additional ingredients may be arbitrarily selected according to the formulation and purpose of use to be appropriately formulated. For example, it may include conventional ingredients such as thickeners, surfactants, moisturizers, abrasives, sweeteners, pH adjusting agents, preservatives, binders, wetting agents, foaming agents, stabilizers, solubilizing agents, vitamins, pigments and flavoring agents.

In addition, the present invention provides a product for oral cavity comprising the above-mentioned deodorant composition. The composition according to the present invention, which uses a plant extract such as rosemary as an active ingredient, is an oral composition that can be contained in all products manufactured and marketed for oral health in general, and there is no limitation on applied oral products. For example, the oral products include, but are not limited to, toothpaste, mouth spray, mouthwash, oral ointment, mouthwash, gargling products, gum, and the like. The oral product of the present invention may be in a liquid, solid, suspension, gel, or aerosol form, but is not limited thereto. In order to apply to the oral product of the present invention, suitable additives, carriers, and the like may be further included in the composition for removing bad breath, and the additives and carriers may be appropriately selected and combined by those skilled in the art. You can.

Plant extracts, such as rosemary, are natural-derived active ingredients that do not pose a problem to human safety, and are excellent in removing sulfur compounds, which are major components of bad breath. In addition, it has a synergistic effect with alcohols having a molecular weight of 65 to 110, and the bad breath removal effect may be further improved. Since these ingredients are hydrophilic, they are also suitable for use in compositions containing water.

1 shows the removal rate of sulfur compounds contained in garlic-derived odor components.
Figure 2 shows the removal rate of sulfur compounds contained in kimchi-derived odor components.
Figure 3 shows the removal rate of sulfur compounds derived from garlic according to the concentration of rosemary extract.
Figure 4 shows the removal rate of sulfur compounds in the rosemary extract according to the extraction solvent.
Figure 5 shows the polyphenol content in the rosemary extract.
Figure 6 shows the effect of PG and 1,3-BG on the effect of removing the sulfur compounds in the rosemary water extract.
Figure 7 shows the effect of the content of PG and 1,3-BG on the sulfur compound removal effect of rosemary water extract.
Figure 8 shows the results showing the bad breath removal effect of the spray containing rosemary extract.
Figure 9 shows the results of evaluating the effect of 1,3-BG on the effect of removing sulfur compounds of various plant extracts.

Hereinafter, the present invention will be described in more detail through examples. These examples are only for explaining the present invention in more detail, it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples.

Example

Experiment method

1. Preparation of extract

To prepare a plant extract, 1 g of plant raw materials and 1 g of extraction solvent were mixed and stored at 50 ° C for 3 hours. Thereafter, the plant material and the extract were first separated by centrifugation at 3,500 rpm for 15 minutes, and then only the extract was completely separated using a filter.

2. Evaluation of sulfur compound removal rate

To evaluate the removal rate of sulfur compounds, odor components were first extracted from garlic and kimchi. Garlic powder was dispersed in purified water to a concentration of 1% (w / w) and then stored at room temperature for 1 hour. Then, by centrifugation, only the supernatant was taken to prepare a garlic odor solution with a garlic odor. Kimchi smell samples were prepared as follows. After adding chopped kimchi to purified water at a concentration of 5% (w / w), it was stored at room temperature for 1 hour. Then, the supernatant was taken by centrifugation. The supernatant separated from kimchi was diluted 50 times with purified water to prepare a kimchi odor solution with kimchi odor.

The concentration of sulfur compounds contained in the garlic odor solution and the kimchi odor solution was quantitatively analyzed using a Halimeter (RH17K, Interscan). In a 50 mL container with a lid, 10 mL each of the garlic odor solution and the kimchi odor solution were added and stored at room temperature for 3 minutes. After that, the gas in the upper space was collected, and the concentration of sulfur compounds was measured using a Halimeter device. In the experiments to confirm the effect of the odor removal candidates on the sulfur compounds, each of the odor removal candidates was added to the garlic odor solution and kimchi odor solution to have a concentration of 0.1% (w / w). After that, after storing at the same temperature for 3 minutes, the concentration of sulfur compounds was measured using a Halimeter.

3. Rosemary  Evaluation of polyphenol reducing power in extract

The reducing power of the polyphenols contained in the rosemary extract was measured using Folin-Ciocalteu's reagent. First, 2 mL of purified water, 0.2 mL of sample solution, and 0.4 mL of Folin-Ciocalteu's reagent were mixed and stored at room temperature for 5 minutes. Thereafter, 4 mL of a 7% concentration aqueous sodium carbonate solution was added. Subsequently, 3.4 mL of purified water was added and stored at room temperature for 2 hours. After storage, the absorbance at 750 nm was measured to evaluate the reducing power of polyphenols. Reducing power was quantified using gallic acid as a standard sample, and rosemary extract was used as a sample solution.

4. Sensory evaluation for removing bad breath

For the evaluation of bad breath removal power, an oral spray composition was prepared with the content (% by weight) of Table 1 below. The content was adjusted with purified water.

Ten professionally trained panelists evaluated the intensity of bad breath after meals in a total of 10 subjects. The spray for removing bad breath was constantly sprayed at 0.1 g, and the intensity of bad breath felt immediately after spraying was quantified.

Experiment result

1.Evaluation of garlic odor and kimchi odor removal

As a result of evaluating the effect of removing 13 kinds of deodorant candidate ingredients for garlic odor, rosemary extract, cinnamon extract, and sodium chlorophyllin showed excellent removal effect as shown in FIG. 1. Among them, rosemary extract showed the best removal effect. In the kimchi odor removal evaluation, as shown in FIG. 2, rosemary extract, green tea extract, chamomile extract, lemon balm extract, chamomile extract, and eucalyptus extract showed excellent removal effects. In particular, the rosemary extract exhibited the best removal rate of kimchi, the same as the effect of removing garlic odor.

2. Rosemary  Evaluation of garlic odor removal of extract

In order to confirm the ability of rosemary extract to remove garlic odor, various rosemary extracts were added to the garlic odor solution, and then the concentration of sulfur compounds generated in the garlic odor solution was measured. As a result, a removal rate graph according to the concentration as in FIG. 3 was obtained. Rosemary extract removed the sulfur compounds contained in the garlic scent, but it was not completely removed even at high concentrations.

3. Extraction solvent  Sulfur compounds Removal power  evaluation

To more clearly remove sulfur compounds, rosemary extract was prepared using a solvent other than water when extracting rosemary. The extraction solvent used is ethanol (Ethanol, EtOH, molecular weight 46.07), ethylene glycol (Ethylene glycol, EG, molecular weight 62.07), dipropylene glycol (Dipropylene glycol, DPG, molecular weight 134.173), hexylene glycol (Hexylene glycol, HG, molecular weight 118.17) ), Isopropyl myristate (IPM, molecular weight 270.451), propylene glycol (PG, molecular weight 76.09), 1,3-butylene glycol (1,3-Butylene glycol, 1,3-BG, molecular weight 90.12). Each extract was mixed in a garlic odor solution so that the final concentration was 0.1%, and the sulfur compound removal rate was evaluated in the same manner as before. As a result, it was confirmed that the rosemary extract using PG and 1,3-BG as shown in FIG. 4 has an excellent sulfur compound removal effect.

4. Investigation of the cause of the increase of sulfur compound removal effect

Rosemary extract contains a large amount of polyphenols, and the contained polyphenols may act to remove sulfur compounds. The content of polyphenols contained in the extract can be quantitatively analyzed using Folin-Ciocalteu's reagent. It was confirmed that the content of the polyphenols contained in the rosemary extract varies depending on the extraction solvent. As a result, as shown in FIG. 5, the polyphenol content in the PG, 1,3-BG extract was not significantly different from other extracts. That is, it was confirmed that the reason why the PG extract and the 1,3-BG extract exhibited a superior sulfur compound removal effect than the water extract was not simply because the extraction efficiency of the polyphenol was increased.

The reason why the rosemary extract using PG and 1,3-BG as an extraction solvent is superior in removing sulfur compounds compared to other rosemary extracts is because the extraction efficiency of polyphenols is not increased, so PG and 1,3-BG are added to the water extract. After the addition, the effect of removing sulfur compounds was evaluated. As a result, PG and 1,3-BG do not have a sulfur compound removal effect, but as shown in FIG. 6, when PG and 1,3-BG were added to the water extract, it was confirmed that the sulfur compound removal effect of the rosemary extract was significantly increased. . That is, it was confirmed that PG and 1,3-BG have a synergistic effect in that the polyphenols present in the rosemary extract act to remove sulfur compounds. In addition, the fact that only PG and 1,3-BG among various alcohol solvents cause this synergistic effect is evaluated to mean that an alcohol solvent having a molecular weight of about 65-110 specifically increases the odor removal effect of rosemary extract. Became.

5. PG  And 1,3-BG content Rosemary  Evaluation of effect on the effect of removing sulfur compounds from extracts

After adding rosemary extract with water (polyphenol content in the extract is about 500 mg GAE / 100 mL DW) in various amounts of PG and 1,3-BG in 0.1% by weight, the effect of these on the removal of sulfur compounds was confirmed. . As a result, as shown in FIG. 7, it was found that an increase in the effect of removing sulfur compounds was observed when the content of PG and 1,3-BG was 0.001% by weight.

6. Rosemary  Evaluation of bad breath removal effect of composition including extract

As a result of confirming how the intensity of bad breath occurring after the actual meal changes after spray spraying, it was confirmed that the composition (example) comprising rosemary extract and 1,3-BG exhibits a significantly better bad breath removal rate (FIG. 8). These results demonstrate that the rosemary extract removes real bad breath with excellent efficiency, as confirmed in the experimental results of 1 to 5 above.

7. Evaluation of the effect of 1,3-BG on the effect of removing sulfur compounds from various plant extracts

After mixing 1 g of cinnamon, green tea, chamomile, lemon balm, and eucalyptus and 1 g of water as an extraction solvent, 0.1% by weight of each plant extract prepared by storing at 50 ° C for 3 hours was prepared. Using 0.1% by weight of 1,3-BG added (w / 0.1% 1,3-BG) and not adding (w / o 0.1% 1,3-BG), they remove sulfur compounds. The effect on the effect was confirmed. The concentration of sulfur compounds contained in the garlic odor solution was quantitatively analyzed using a Halimeter (RH17K, Interscan), and the results are shown in FIG. 9.

As a result of the experiment, as shown in FIG. 9, when 1,3-BG was added to various plant extracts, it was confirmed that the effect of removing the sulfur compounds of the plant extract was greatly increased. That is, it was confirmed that 1,3-BG has a synergistic effect in removing the sulfur compound from polyphenols present in various plant extracts as well as rosemary.

Claims (18)

A composition for removing bad breath comprising a plant extract. The composition of claim 1, wherein the plant extract is at least one selected from the group consisting of rosemary, celestial, Angelica, cinnamon, green tea, celery, eucalyptus, calendula, chamomile, and lemon balm extracts. The composition of claim 1, wherein the plant extract is a rosemary extract. The composition of claim 1, wherein the composition further comprises an alcohol having a molecular weight of 65 to 110. The method of claim 4, wherein the alcohol having a molecular weight of 65 to 110 is propylene glycol (propylene glycol), butylene glycol (butylene glycol), butanol (butanol), isobutyl alcohol (isobutyl alcohol), pentanol (pentanol), iso Characterized in that at least one selected from the group consisting of pentyl alcohol, hexanol, 4-methyl-1-pentanol and pentylene glycol Composition. The composition of claim 4, wherein the alcohol having a molecular weight of 65 to 110 is not an extraction solvent for a plant extract. The composition of claim 4, wherein the alcohol is contained in an amount of 0.001 to 10% by weight in the total composition. In claim 1, the bad breath is characterized in that the smell of garlic or kimchi. The method of claim 1, wherein the plant extract is water, alcohol, acetic acid, alkyl esters, ketones, alkanes, cycloalkanes, ethers, benzene, alkyl sulfide, chloroform and one or more solvent extracts selected from the group consisting of carbon tetrachloride, characterized in that Composition. The composition of claim 1, wherein the plant extract is a water extract. The composition of claim 1, wherein the content of polyphenols contained in the plant extract is 10 to 10,000 mg gallic acid equivalent / 100 mL purified water. The composition of claim 1, wherein the plant extract is a vacuum distilled powder, freeze dried powder or spray dried powder. A composition for removing bad breath comprising a plant extract, wherein the extract is extracted using alcohol having a molecular weight of 65 to 110 as an extraction solvent. The composition according to any one of claims 1 to 13, wherein the composition is a pharmaceutical composition. The composition according to any one of claims 1 to 13, wherein the composition is a quasi-drug composition. The composition according to any one of claims 1 to 13, wherein the composition is a cosmetic composition. An oral product comprising the composition according to claim 1. 18. The oral product according to claim 17, wherein the oral product is selected from the group consisting of toothpaste, gargling product, gum, oral soap spray, oral ointment, mouthwash and mouthwash.

Images