KR101984166B1 - Cosmetic composition for reducing skin stimulus containing extracts of lophatherum gracile, humulus japonicus and dianthus chinensis - Google Patents

Abstract

The present invention relates to a cosmetic composition having an effect of alleviating skin irritation caused by vitamin C, and more particularly to a cosmetic composition for alleviating skin irritation by alleviating irritation caused by contact of the vitamin C with the skin .

Description

TECHNICAL FIELD The present invention relates to a cosmetic composition for skin irritation mitigation, which comprises an extract of a carnauba,

The present invention relates to a cosmetic composition which contains at least one natural plant extract selected from the group consisting of an extract of Chrysanthemum morifolium, Chrysanthemum morifolium extract, and a Gamma-extract, and has an effect of relieving skin irritation caused by highly concentrated vitamin C.

Vitamin C is one of the trace elements for maintaining the function and health of the human body and is also called ascorbic acid. It helps the human body resist infection, heal wounds, keep tissues healthy, and prevent cellular damage by free radicals as one of the antioxidants. Fruits, and vegetables. Especially, it is contained in persimmon, tangerine, tomato, broccoli, spinach, strawberry, melon, potato and so on.

These vitamin C also play an important role in maintaining healthy skin. It can promote the synthesis of skin collagen, and by ingestion or application to the skin, there is a research result that vitamin C can also help prevent photoaging by ultraviolet rays.

Therefore, when vitamin C deficiency, collagen formation due to collagen biosynthesis is formed, the skin becomes rough, and resistance to infection becomes poor. In addition, capillary hemorrhage and various skin lesions occur, and in the case of long-term deficiency, serious diseases such as blood clots may be caused. For this reason, it is recommended to use the vitamin C containing cosmetics to protect the skin.

These vitamin C can help skin care with excellent antioxidant and anti-pigmentation function. However, vitamin C generally begins to oxidize when it comes in contact with air, heat, and moisture, and cosmetics containing vitamin C above a certain concentration cause skin irritation. Therefore, there is a desperate need for a cosmetic which contains vitamin C and can minimize irritation to the skin.

The present invention relates to a cosmetic composition containing a high-concentrated vitamin C, which is applied to the skin to prevent the vitamin C itself from being irritated to the skin, so that a good component of the vitamin C can be stably absorbed to the skin And to provide a cosmetic composition containing the same.

In order to accomplish the object of the present invention, the present invention provides a cosmetic composition comprising at least one extract of three natural plants from the leaves of Phellinus linteus, Rhodiola, and Staphylococcus aureus which alleviate skin irritation caused by vitamin C.

The present invention can alleviate skin irritation caused by vitamin C by reducing skin irritation caused by stimulating vitamin C.

In order to accomplish the above object, the present invention provides a cosmetic composition for relieving skin irritation containing at least one extract of the following three natural plants, particularly a cosmetic composition for relieving skin irritation caused by stimulated vitamin C.

The three natural plants used in the present invention are Lophatherum gracile Bronghiart, Humulus japonicus Siebold et Zuccarini, and Dianthus chinensis Linne.
Lophatherum gracile Bronghiart is the surface of Lophatherum gracile Brongniart (Gramineae) before flowering. Its length is 25 ~ 75cm. The stem is cylindrical with rounded edges. The folded side is empty. The leaf sheath is split and the leaves are shrunken and lined with lanceolate, 5 ~ 20cm in length and 1 ~ 3.5cm in width. Outer surface is light green to yellowish green, leaf vein is vein side by side, and thin vein is transverse to form rectangle net shape. Quality is light and soft. There is little smell and the taste is cool.

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Humulus japonicus Siebold et Zuccarini is the underside of Humulus japonicus Siebold et Zuccarini (Moraceae). It is mainly composed of foliage with vine stalks and some with fruit. The length is not fixed, but it is 2 ~ 3m. Leaves are light green ~ gray green, curled and shrunken. When spread, they are split into 5 ~ 7 pieces with palm shape and 5 ~ 7cm in length. The leaves are opposite, the cracked leaves are egg-shaped or lanceolate, with regular sawtooth on the edge, coarse hairs on both sides and glandular on the underside. The stems and petiole are dense with short, thick spines. There is a little grass smell and the taste is a little bitter.

Dianthus chinensis Linne, Dianthus chinensis Linne and Dianthus superbus Linnevar. It is above ground of longicalycinus Williams (Coryophyllaceae). The stem has a thin cylindrical shape, has branches and is 30 ~ 50cm long. Outer surface is light green ~ yellow green and there is no hair. Leaves are lanceolate and face slightly raised nodes. Flowers or fruit hang on the ends of the stems and branches. Calyx is cylindrical and its tip is split into 5, yellowish green and 1 ~ 2cm long. The fruit is capsule and the seed is brown. There is little smell and the taste is a little conspicuous.

No studies have been reported on the effect of vitamin C on the skin irritation mitigation effect of the above-mentioned three plants.

The natural plant extract contains 0.1 to 10.0% by weight of the total weight of the cosmetic composition, thereby alleviating skin irritation to stimulated vitamin C. Each of the above extracts can be prepared as a single component of each natural plant, and a mixed extract obtained by mixing together natural plants at a predetermined ratio can be prepared.

Preferably, the mixed extract of the present invention is prepared by mixing a mixture of Baechu-Yaburi: Yucchosu-gum: 0.5 to 2.0: 0.5 to 2.0: 0.5 to 2.0, more preferably 1: 1: 1 < / RTI > by weight.

The extract of natural plant of the present invention can be prepared by using a conventional solvent under the conditions of ordinary temperature and pressure according to a conventional method known in the art. Preferably, (a) water, 1- Propylene and butanol), propylene glycol, 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform , Hexane, and mixtures thereof. ≪ / RTI >

In the present invention, a solvent extraction method using an extraction solvent was used. Preferably ethanol, 70% (v / v) ethanol or water, and most preferably 70% (v / v) ethanol.

[Preparation Example 1] Preparation of the single extract of the present invention

100 g of the ground portion of the pine bark was cut into 99% ethanol, heated at 100 ° C for 8 hours, extracted, and the extract residue was firstly filtered using a cotton swab and then subjected to secondary filtration using Wattmann # 4 filter paper The precipitate was removed to give a single extract.

[Preparation Example 2] Preparation of the herbal extract of the present invention

100 g of the above-ground part was chopped into 99% ethanol and heated at 100 ° C for 8 hours to extract. The extract residue was firstly filtered using a cotton cloth, followed by secondary filtration using Wattmann # 4 filter paper to obtain a precipitate To obtain a single extract.

[Production Example 3] Preparation of the extract of the goat mackerel of the present invention

100 g of the ground portion of the vein was cut into a 99% ethanol and heated at 100 ° C for 8 hours to extract. The extract residue was firstly filtered using a cotton swab and then subjected to secondary filtration using a Wattmann # 4 filter paper to obtain a precipitate To obtain a single extract.

[Preparation Example 4] Preparation of the mixed extract of Dahshyeok, Yuko, and Goat of the present invention

After the sample was collected, 100 g of the ground surface portion of 100% of the ground surface, 100 g of the ground surface portion and 100 g of the ground surface portion were mixed in a weight ratio of 1: 1: 1 and the mixture was heated at 100 ° C. for 8 hours in 99% ethanol, The extracts were firstly filtered and then filtered using 'Wattman # 4 filter paper' to remove precipitates to obtain a mixed extract.

Hereinafter, only the essence formulation is exemplified as the agent of the present invention. However, the formulation including the cosmetic composition of the present invention is not limited thereto, and may be used in the form of a cream, a massage cream, a lotion, a skin lotion, a pack, a cleansing foam, .

[Formulation Examples 1 to 15 and Comparative Formulation Examples 1 to 3] Preparation of an essence formulation

Essential compositions of Formulation Examples 1 to 15 and Comparative Formulation Examples 1 to 3 were prepared according to a conventional method using the ingredients described in Tables 1 to 3 below.

Raw material name Content (% by weight) Formulation Example 1 Formulation Example 2 Formulation Example 3 Formulation Example 4 Formulation Example 5 Comparative Formulation Example 1 Production Example 1 1.0 - - 0.33 - Production Example 2 - 1.0 - 0.33 - Production Example 3 - - 1.0 0.33 - Production Example 4 1.0 Vitamin C 5 5 5 5 5 5 Concentrated glycerin 15.0 15.0 15.0 15.0 15.0 15.0 1,3-butylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 Alatoin 0.1 0.1 0.1 0.1 0.1 0.1 ethanol 7.0 7.0 7.0 7.0 7.0 7.0 Para-oxybenzoic acid 0.15 0.15 0.15 0.15 0.15 0.15 Triethanolamine 0.15 0.15 0.15 0.15 0.15 0.15 Holly oxyethylene hardened castor oil One One One One One One Tocopheryl acetate 0.5 0.5 0.5 0.5 0.5 0.5 Carboxyvinyl polymer 0.15 0.15 0.15 0.15 0.15 0.15 Spices a very small amount a very small amount a very small amount a very small amount a very small amount a very small amount Purified water Balance Balance Balance Balance Balance Balance

Raw material name Content (% by weight) Formulation Example 6 Formulation Example 7 Formulation Example 8 Formulation Example 9 Formulation Example 10 Comparative Formulation Example 2 Production Example 1 1.0 - - 0.33 - Production Example 2 - 1.0 - 0.33 - Production Example 3 - - 1.0 0.33 - Production Example 4 1.0 Vitamin C 10 10 10 10 10 10 Concentrated glycerin 15.0 15.0 15.0 15.0 15.0 15.0 1,3-butylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 Alatoin 0.1 0.1 0.1 0.1 0.1 0.1 ethanol 7.0 7.0 7.0 7.0 7.0 7.0 Para-oxybenzoic acid 0.15 0.15 0.15 0.15 0.15 0.15 Triethanolamine 0.15 0.15 0.15 0.15 0.15 0.15 Holly oxyethylene hardened castor oil One One One One One One Tocopheryl acetate 0.5 0.5 0.5 0.5 0.5 0.5 Carboxyvinyl polymer 0.15 0.15 0.15 0.15 0.15 0.15 Spices a very small amount a very small amount a very small amount a very small amount a very small amount a very small amount Purified water Balance Balance Balance Balance Balance Balance

Raw material name Content (% by weight) Formulation Example 11 Formulation Example 12 Formulation Example 13 Formulation Example 14 Formulation Example 15 Comparative Formulation Example 3 Production Example 1 1.0 - - 0.33 - Production Example 2 - 1.0 - 0.33 - Production Example 3 - - 1.0 0.33 - Production Example 4 1.0 Vitamin C 20 20 20 20 20 20 Concentrated glycerin 15.0 15.0 15.0 15.0 15.0 15.0 1,3-butylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 Alatoin 0.1 0.1 0.1 0.1 0.1 0.1 ethanol 7.0 7.0 7.0 7.0 7.0 7.0 Para-oxybenzoic acid 0.15 0.15 0.15 0.15 0.15 0.15 Triethanolamine 0.15 0.15 0.15 0.15 0.15 0.15 Holly oxyethylene hardened castor oil One One One One One One Tocopheryl acetate 0.5 0.5 0.5 0.5 0.5 0.5 Carboxyvinyl polymer 0.15 0.15 0.15 0.15 0.15 0.15 Spices a very small amount a very small amount a very small amount a very small amount a very small amount a very small amount Purified water Balance Balance Balance Balance Balance Balance

[Test Example 1] Evaluation of skin irritation mitigation efficacy through human body application test (patch test)

The subjects were visited three times (before the start of the test, on the day of removing the patches, after 24 hours after the removal of the patches) during the period of applying the human body and judged whether the skin was irritated. At the first visit, subjects were subjected to a skin patch test on the subject's back using an IQ chamber (Chemotechnique Diagnostics, Sweden). The subjects were applied to the shoulder bones and the waist line around the spine using IQ chambers.

The test site was wiped with 70% ethanol and dried. Then, 20 μl of the test sample prepared according to Tables 1 to 3 was dropped into the IQ chamber, and the test sample was fixed on the test site. After 24 hours, the test area was marked with a marking pen. After 30 minutes, the test area was observed after 24 hours.

- No reaction 0 . Faint light erythema 0.5 ± Weak erythema One + Clear erythema, papules and small follicles 2 ++ Severe erythema, alveoli 6 +++ Scab formation 12

The degree of skin irritation in Test Example 1 was shown according to the evaluation standard as shown in Table 4, and the skin irritation rate was calculated by the following calculation formula and shown in Table 5.

[Equation 1]

Skin irritation was judged to be non-irritation when the irritation rate was 0.0, irregular irritation in the range of 0.1 to 1.0, mild irritation in the range of 1.0 to 1.7, moderate irritation in the range of 1.7 to 2.5, and irritation in the irritation ratio of 2.5 or more.

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Composition Skin irritation rate Irritation degree Formulation Example 1 1.25 Light stimulus Formulation Example 2 1.39 Light stimulus Formulation Example 3 1.39 Light stimulus Formulation Example 4 1.11 Light stimulus Formulation Example 5 0.83 Irritation Formulation Example 6 1.67 Light stimulus Formulation Example 7 1.81 Moderate irritation Formulation Example 8 1.67 Light stimulus Formulation Example 9 1.53 Light stimulus Formulation Example 10 0.97 Irritation Formulation Example 11 2.08 Moderate irritation Formulation Example 12 2.36 Moderate irritation Formulation Example 13 2.22 Moderate irritation Formulation Example 14 1.67 Light stimulus Formulation Example 15 0.97 Irritation Comparative Formulation Example 1 1.53 Light stimulus Comparative Formulation Example 2 2.08 Moderate irritation Comparative Formulation Example 3 2.64 River stimulation

&Quot; (2) "

Stimulation relaxation rate (%) = 100 x (1- {skin irritation rate in formulation example} / {skin irritation rate in comparative formulation example}

Composition Stimulus relaxation rate (%) Comparative Formulation Example 1 - Formulation Example 1 18.30 Formulation Example 2 9.15 Formulation Example 3 9.15 Formulation Example 4 27.45 Formulation Example 5 45.75 Comparative Formulation Example 2 - Formulation Example 6 19.71 Formulation Example 7 12.98 Formulation Example 8 19.71 Formulation Example 9 26.44 Formulation Example 10 53.37 Comparative Formulation Example 3 - Formulation Example 11 21.21 Formulation Example 12 10.61 Formulation Example 13 15.91 Formulation Example 14 36.74 Formulation Example 15 63.26

As can be seen from Test Example 1 of the present invention, it was confirmed that the composition containing vitamin C at a certain concentration (20.0%) or more induces a strong stimulus to the skin. Referring to Table 5, Was found to have a significantly lower skin irritation rate than cosmetic compositions containing no cosmetic ingredients. In particular, as can be seen from the skin irritation rates of the cosmetic preparations of Formulation Examples 4, 9 and 14, the extract of the present invention was found to have a more stimulating effect as the components of the respective extracts were contained together.

As shown in Table 6 together with Table 5, the cosmetic compositions containing the mixed extracts obtained by mixing together a certain ratio of the carrageenan, rhinocerospora, and rhinoceros of the present invention as in the cosmetic compositions of Forms 5, 10 and 15 As the content ratio of vitamin C increased, it was proportional to the content ratio of vitamin C and the effect of stimulation relaxation was further increased.

Claims (5)

A cosmetic composition for alleviating skin irritation caused by vitamin C, which comprises at least one extract from natural plant group consisting of carnauba frutescens, rhizomes and veins, and vitamin C. The cosmetic composition for relieving skin irritation caused by vitamin C according to claim 1, wherein the cosmetic composition prevents the skin from being damaged by alleviating skin irritation caused by vitamin C by the extract. The cosmetic composition for relieving skin irritation caused by vitamin C according to any one of claims 1 to 3, wherein the extract is contained in an amount of 0.1 to 10.0% by weight based on the total weight of the composition. The cosmetic composition for relieving skin irritation caused by vitamin C according to any one of claims 1 to 3, wherein the cosmetic composition contains a mixed extract of carnauba, rhinoceros, and oranges as an active ingredient. [Claim 5] The cosmetic composition for relieving skin irritation caused by vitamin C according to claim 4, wherein the mixed extract is mixed at a weight ratio of 0.5 to 2.0: 0.5 to 2.0: 0.5 to 2.0.