KR20200020727A - C5a 활성의 억제제를 사용한 염증 질병의 치료 - Google Patents
C5a 활성의 억제제를 사용한 염증 질병의 치료 Download PDFInfo
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- KR20200020727A KR20200020727A KR1020197038211A KR20197038211A KR20200020727A KR 20200020727 A KR20200020727 A KR 20200020727A KR 1020197038211 A KR1020197038211 A KR 1020197038211A KR 20197038211 A KR20197038211 A KR 20197038211A KR 20200020727 A KR20200020727 A KR 20200020727A
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| PCT/EP2018/065676 WO2018234118A1 (en) | 2017-06-23 | 2018-06-13 | Treatment of inflammatory diseases with inhibitors of c5a activity |
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| IL296036A (en) * | 2020-03-27 | 2022-10-01 | Inflarx Gmbh | Inhibitors of c5a for the treatment of corona virus infection |
| WO2021259160A1 (en) * | 2020-06-24 | 2021-12-30 | Staidson (Beijing) Biopharmaceuticals Co., Ltd. | Antibodies specifically recognizing c5a and uses thereof |
| JP2024502863A (ja) | 2021-01-13 | 2024-01-23 | ビステラ， インコーポレイテッド | ヒト化補体５ａ受容体１抗体及びその使用方法 |
| US12180274B2 (en) | 2023-05-26 | 2024-12-31 | Inflarx Gmbh | Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity |
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| US4704355A (en) | 1985-03-27 | 1987-11-03 | New Horizons Diagnostics Corporation | Assay utilizing ATP encapsulated within liposome particles |
| CA2025907A1 (en) | 1989-09-21 | 1991-03-22 | Franklin D. Collins | Method of transporting compositions across the blood brain barrier |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| AUPO755097A0 (en) | 1997-06-25 | 1997-07-17 | University Of Queensland, The | Receptor agonist and antagonist |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| AUPR833401A0 (en) * | 2001-10-17 | 2001-11-08 | University Of Queensland, The | G protein-coupled receptor antagonists |
| DK2860251T3 (en) | 2004-02-12 | 2018-06-06 | Archemix Llc | APTAPMER PHARMACEUTICALS USEFUL IN TREATMENT OF COMPLEMENT-RELATED DISEASES |
| MXPA06011051A (es) * | 2004-03-26 | 2007-04-13 | Promics Pty Ltd | Tratamiento de condiciones neurologicas usando complemento de moduladores del receptor c5a. |
| CN101553244B (zh) * | 2006-07-21 | 2013-01-02 | 普罗米克斯有限公司 | 内膜增生和相关病状的治疗 |
| GB0617734D0 (en) | 2006-09-08 | 2006-10-18 | Evolutec Ltd | Method of treating peripheral nerve disorders |
| TWI465434B (zh) * | 2008-12-22 | 2014-12-21 | Chemocentryx Inc | Ｃ５ａＲ拮抗劑 |
| GB0905790D0 (en) * | 2009-04-03 | 2009-05-20 | Alligator Bioscience Ab | Novel polypeptides and use thereof |
| EP2327725A1 (en) | 2009-11-26 | 2011-06-01 | InflaRx GmbH | Anti-C5a binding moieties with high blocking activity |
| HUE033644T2 (en) | 2010-06-24 | 2017-12-28 | Chemocentryx Inc | C5AR antagonists |
| SMT201700552T1 (it) * | 2013-03-14 | 2018-01-11 | Alnylam Pharmaceuticals Inc | COMPOSIZIONI DI iRNA DEL COMPONENTE DEL COMPLEMENTO C5 E LORO METODI DI USO |
| US20160060351A1 (en) * | 2013-05-08 | 2016-03-03 | Novo Nordisk A/S | Use of C5AR Antagonists |
| EP3119802B1 (en) * | 2014-03-20 | 2019-12-04 | InflaRx GmbH | Inhibitors of c5a for the treatment of viral pneumonia |
| EP3194596A1 (en) | 2014-09-16 | 2017-07-26 | Alnylam Pharmaceuticals, Inc. | Complement component c5 irna compositions and methods of use thereof |
| US10544209B2 (en) | 2014-10-15 | 2020-01-28 | Alexion Pharmaceuticals, Inc. | Methods of replicating a large scale eculizumab production cell culture |
| FR3030515B1 (fr) * | 2014-12-23 | 2017-01-20 | Galderma Res & Dev | Nouveaux composes antagonistes des recepteurs cxcr1 et cxcr2 aux chimiokines, et leur utilisation dans le traitement de pathologies mediees par des chimiokines |
| US20180142010A1 (en) | 2015-06-26 | 2018-05-24 | Alexion Pharmaceuticals, Inc. | Method for treating a patient in compliance with vaccination with eculizumab or an eculizumab variant |
| JP7121722B2 (ja) | 2016-04-04 | 2022-08-18 | ケモセントリックス，インコーポレイティド | 可溶性Ｃ５ａＲアンタゴニスト |
| ES2893769T3 (es) * | 2017-04-03 | 2022-02-10 | Inflarx Gmbh | Tratamiento de enfermedades inflamatorias con inhibidores de la actividad de C5a |
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