KR20200012949A - 과민성 방광의 치료를 위한 비베그론의 용도 - Google Patents
과민성 방광의 치료를 위한 비베그론의 용도 Download PDFInfo
- Publication number
- KR20200012949A KR20200012949A KR1020197038625A KR20197038625A KR20200012949A KR 20200012949 A KR20200012949 A KR 20200012949A KR 1020197038625 A KR1020197038625 A KR 1020197038625A KR 20197038625 A KR20197038625 A KR 20197038625A KR 20200012949 A KR20200012949 A KR 20200012949A
- Authority
- KR
- South Korea
- Prior art keywords
- subject
- vibegron
- dose
- bibegron
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020257020007A KR20250099259A (ko) | 2017-06-06 | 2018-06-06 | 과민성 방광의 치료를 위한 비베그론의 용도 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762515996P | 2017-06-06 | 2017-06-06 | |
| US62/515,996 | 2017-06-06 | ||
| US201862635146P | 2018-02-26 | 2018-02-26 | |
| US62/635,146 | 2018-02-26 | ||
| US201862637961P | 2018-03-02 | 2018-03-02 | |
| US62/637,961 | 2018-03-02 | ||
| PCT/IB2018/054069 WO2018224989A1 (en) | 2017-06-06 | 2018-06-06 | Use of vibegron to treat overactive bladder |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257020007A Division KR20250099259A (ko) | 2017-06-06 | 2018-06-06 | 과민성 방광의 치료를 위한 비베그론의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20200012949A true KR20200012949A (ko) | 2020-02-05 |
Family
ID=62815097
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197038625A Ceased KR20200012949A (ko) | 2017-06-06 | 2018-06-06 | 과민성 방광의 치료를 위한 비베그론의 용도 |
| KR1020257020007A Pending KR20250099259A (ko) | 2017-06-06 | 2018-06-06 | 과민성 방광의 치료를 위한 비베그론의 용도 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257020007A Pending KR20250099259A (ko) | 2017-06-06 | 2018-06-06 | 과민성 방광의 치료를 위한 비베그론의 용도 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US12102638B2 (https=) |
| EP (2) | EP3634420A1 (https=) |
| JP (3) | JP7682605B2 (https=) |
| KR (2) | KR20200012949A (https=) |
| CN (3) | CN117695286A (https=) |
| AU (2) | AU2018282104B2 (https=) |
| BR (1) | BR112019025636A2 (https=) |
| CA (1) | CA3064989A1 (https=) |
| CL (1) | CL2019003533A1 (https=) |
| IL (2) | IL317220A (https=) |
| MX (1) | MX2022015629A (https=) |
| PH (1) | PH12019502651A1 (https=) |
| WO (1) | WO2018224989A1 (https=) |
| ZA (1) | ZA202000028B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102020124101A1 (de) | 2020-02-04 | 2021-08-05 | Samsung Electronics Co., Ltd. | Elektronische vorrichtung mit einer speichervorrichtung und trainingsverfahren |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102735800B1 (ko) * | 2017-12-21 | 2024-11-28 | 교린 세이야쿠 가부시키가이샤 | 야간빈뇨 치료제 |
| SG11202103662VA (en) * | 2018-12-05 | 2021-06-29 | Urovant Sciences Gmbh | Vibegron for the treatment of overactive bladder symptoms |
| JP2022524576A (ja) * | 2019-03-18 | 2022-05-09 | ウロバント サイエンシズ ゲーエムベーハー | 過活動膀胱を処置するためのビベグロンの使用 |
| CA3202926A1 (en) * | 2020-12-22 | 2022-06-30 | Paul N. Mudd Jr. | Methods of monitoring digoxin with concomitant use of vibegron to treat overactive bladder |
| WO2025262600A1 (en) | 2024-06-17 | 2025-12-26 | Urovant Sciences Gmbh | Crystalline form of vibegron hemihydrate |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE266639T1 (de) | 1997-10-17 | 2004-05-15 | Yamanouchi Pharma Co Ltd | Amidderivate oder deren salze |
| GB9812709D0 (en) | 1998-06-13 | 1998-08-12 | Glaxo Group Ltd | Chemical compounds |
| US6562375B1 (en) | 1999-08-04 | 2003-05-13 | Yamanouchi Pharmaceuticals, Co., Ltd. | Stable pharmaceutical composition for oral use |
| GB0015246D0 (en) * | 2000-06-22 | 2000-08-16 | Astrazeneca Ab | Method for the treatment of urinary incontinence |
| US6525202B2 (en) | 2000-07-17 | 2003-02-25 | Wyeth | Cyclic amine phenyl beta-3 adrenergic receptor agonists |
| US7342117B2 (en) | 2001-10-30 | 2008-03-11 | Astellas Pharma Inc. | α-form or β-form crystal of acetanilide derivative |
| DOP2003000587A (es) | 2002-02-27 | 2003-08-30 | Pfizer Prod Inc | AGONISTAS DEL RECEPTOR ß3-ADRENERGICO |
| DK1559427T3 (da) | 2002-11-07 | 2011-04-26 | Astellas Pharma Inc | Lægemiddel til overaktiv blære omfattende eddikesyreanilidderivat som den aktive bestanddel |
| DK1620085T3 (da) | 2003-05-05 | 2008-11-24 | Kissei Pharmaceutical | Anvendelse af phenoxyacetatsyrederivater til behandling af hyperaktiv blære |
| FR2874011B1 (fr) | 2004-08-03 | 2007-06-15 | Sanofi Synthelabo | Derives de sulfonamides, leur preparation et leur application en therapeutique |
| CA2682676A1 (en) | 2007-04-19 | 2008-10-30 | Novartis Ag | Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5 |
| EP2198018B1 (en) | 2007-09-13 | 2013-11-20 | Codexis, Inc. | Ketoreductase polypeptides for the reduction of acetophenones |
| CA2704298C (en) | 2007-11-02 | 2015-07-21 | Astellas Pharma Inc. | Pharmaceutical composition for treating overactive bladder |
| PE20091825A1 (es) | 2008-04-04 | 2009-12-04 | Merck & Co Inc | Hidroximetil pirrolidinas como agonistas del receptor adrenergico beta 3 |
| US8273554B2 (en) | 2008-08-29 | 2012-09-25 | Codexis, Inc. | Ketoreductase polypeptides for the stereoselective production of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one |
| WO2011043942A1 (en) | 2009-10-07 | 2011-04-14 | Merck Sharp & Dohme Corp. | Combination therapy using a beta 3 adrenergic receptor agonist and an antimuscarinic agent |
| WO2011137054A1 (en) | 2010-04-30 | 2011-11-03 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| US9522129B2 (en) | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
| AU2011285928B9 (en) | 2010-08-03 | 2018-08-02 | B3Ar Therapeutics, Inc. | Combinations of beta - 3 adrenergic receptor agonists and muscarinic receptor antagonists for treating overactive bladder |
| AU2012323890A1 (en) | 2011-10-14 | 2014-05-29 | Array Biopharma Inc. | Polymorphs of arry-380, a selective ErbB2 inhibitor and pharmaceutical compositions containing them |
| ES2584427T3 (es) | 2011-10-27 | 2016-09-27 | Merck Sharp & Dohme Corp. | Proceso para la preparación de agonistas beta 3 y productos intermedios |
| WO2013062881A1 (en) | 2011-10-27 | 2013-05-02 | Merck Sharp & Dohme Corp. | Process for making beta 3 agonists and intermediates |
| IN2014CN04470A (https=) | 2011-11-18 | 2015-09-04 | Codexis Inc | |
| EP2606894A1 (en) | 2011-12-20 | 2013-06-26 | Sanofi | Novel therapeutic use of p75 receptor antagonists |
| UA112028C2 (uk) | 2012-12-14 | 2016-07-11 | Пфайзер Лімітед | Похідні імідазопіридазину як модулятори гамка-рецептора |
| RS59402B1 (sr) | 2013-03-15 | 2019-11-29 | Merck Sharp & Dohme | Postupak za pripremu beta 3 agonista i međuproizvoda |
| HK1245117A1 (zh) | 2014-12-03 | 2018-08-24 | Velicept Therapeutics, Inc. | 使用调节释放索拉贝隆用於下尿路症状的组合物和方法 |
| ES2967863T3 (es) | 2015-10-23 | 2024-05-06 | B3Ar Therapeutics Inc | Ion dipolar de solabegron y usos del mismo |
| US20170348288A1 (en) | 2016-06-03 | 2017-12-07 | Velicept Therapeutics, Inc. | Dosing regimens for beta-3 adrenoceptor agonists and anti-muscarinic agents for the treatment and prevention of lower urinary tract symptoms and overactive bladder |
| EP3463307A4 (en) | 2016-06-03 | 2020-01-15 | Velicept Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR USE OF SOLABEGRON WITH MODIFIED RELEASE FOR SYMPTOMS OF THE LOWER URINARY PATHWAYS |
| JP7670461B2 (ja) | 2017-06-06 | 2025-04-30 | ウロバント サイエンシズ ゲゼルシャフト ミット ベシュレンクター ハフトゥング | 過活動膀胱の治療のためのビベグロンの投薬 |
| KR102735800B1 (ko) | 2017-12-21 | 2024-11-28 | 교린 세이야쿠 가부시키가이샤 | 야간빈뇨 치료제 |
| SG11202010683PA (en) | 2018-05-23 | 2020-12-30 | Urovant Sciences Gmbh | Use of vibegron to treat pain associated with irritable bowel syndrome |
| SG11202103662VA (en) | 2018-12-05 | 2021-06-29 | Urovant Sciences Gmbh | Vibegron for the treatment of overactive bladder symptoms |
| JP2022524576A (ja) | 2019-03-18 | 2022-05-09 | ウロバント サイエンシズ ゲーエムベーハー | 過活動膀胱を処置するためのビベグロンの使用 |
| CA3202926A1 (en) | 2020-12-22 | 2022-06-30 | Paul N. Mudd Jr. | Methods of monitoring digoxin with concomitant use of vibegron to treat overactive bladder |
| TW202245781A (zh) | 2021-02-16 | 2022-12-01 | 瑞士商優洛凡特科學公司 | 用維貝格龍(vibegron)治療心臟衰竭之方法 |
-
2018
- 2018-06-06 EP EP18737031.7A patent/EP3634420A1/en not_active Withdrawn
- 2018-06-06 KR KR1020197038625A patent/KR20200012949A/ko not_active Ceased
- 2018-06-06 WO PCT/IB2018/054069 patent/WO2018224989A1/en not_active Ceased
- 2018-06-06 JP JP2019567995A patent/JP7682605B2/ja active Active
- 2018-06-06 IL IL317220A patent/IL317220A/en unknown
- 2018-06-06 AU AU2018282104A patent/AU2018282104B2/en active Active
- 2018-06-06 US US16/620,179 patent/US12102638B2/en active Active
- 2018-06-06 CA CA3064989A patent/CA3064989A1/en active Pending
- 2018-06-06 CN CN202311666042.4A patent/CN117695286A/zh active Pending
- 2018-06-06 EP EP24181939.0A patent/EP4410295A3/en active Pending
- 2018-06-06 CN CN202311666478.3A patent/CN117695287A/zh active Pending
- 2018-06-06 CN CN201880045540.8A patent/CN110869022A/zh active Pending
- 2018-06-06 KR KR1020257020007A patent/KR20250099259A/ko active Pending
- 2018-06-06 BR BR112019025636-9A patent/BR112019025636A2/pt not_active Application Discontinuation
-
2019
- 2019-11-25 PH PH12019502651A patent/PH12019502651A1/en unknown
- 2019-12-04 MX MX2022015629A patent/MX2022015629A/es unknown
- 2019-12-04 CL CL2019003533A patent/CL2019003533A1/es unknown
- 2019-12-04 IL IL271164A patent/IL271164A/en unknown
-
2020
- 2020-01-02 ZA ZA2020/00028A patent/ZA202000028B/en unknown
-
2023
- 2023-03-01 JP JP2023030625A patent/JP2023071826A/ja active Pending
-
2024
- 2024-07-03 AU AU2024204591A patent/AU2024204591A1/en active Pending
-
2025
- 2025-01-15 JP JP2025005498A patent/JP2025063196A/ja active Pending
- 2025-04-25 US US19/190,296 patent/US20260014158A1/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102020124101A1 (de) | 2020-02-04 | 2021-08-05 | Samsung Electronics Co., Ltd. | Elektronische vorrichtung mit einer speichervorrichtung und trainingsverfahren |
Also Published As
| Publication number | Publication date |
|---|---|
| US20210077495A1 (en) | 2021-03-18 |
| IL271164A (en) | 2020-01-30 |
| CN110869022A (zh) | 2020-03-06 |
| MX2022015629A (es) | 2023-01-11 |
| US20260014158A1 (en) | 2026-01-15 |
| JP2025063196A (ja) | 2025-04-15 |
| JP2020522560A (ja) | 2020-07-30 |
| ZA202000028B (en) | 2025-09-25 |
| WO2018224989A1 (en) | 2018-12-13 |
| JP2023071826A (ja) | 2023-05-23 |
| CL2019003533A1 (es) | 2020-06-26 |
| AU2018282104B2 (en) | 2024-07-11 |
| JP7682605B2 (ja) | 2025-05-26 |
| KR20250099259A (ko) | 2025-07-01 |
| EP4410295A3 (en) | 2024-10-16 |
| AU2024204591A1 (en) | 2024-07-18 |
| IL317220A (en) | 2025-01-01 |
| US12102638B2 (en) | 2024-10-01 |
| EP4410295A2 (en) | 2024-08-07 |
| CA3064989A1 (en) | 2018-12-13 |
| AU2018282104A1 (en) | 2019-12-12 |
| CN117695287A (zh) | 2024-03-15 |
| PH12019502651A1 (en) | 2020-06-08 |
| CN117695286A (zh) | 2024-03-15 |
| BR112019025636A2 (pt) | 2020-08-25 |
| EP3634420A1 (en) | 2020-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
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