KR20190135000A - Aav 벡터를 기반으로 하는 인플루엔자 백신 - Google Patents

Aav 벡터를 기반으로 하는 인플루엔자 백신 Download PDF

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KR20190135000A
KR20190135000A KR1020197027793A KR20197027793A KR20190135000A KR 20190135000 A KR20190135000 A KR 20190135000A KR 1020197027793 A KR1020197027793 A KR 1020197027793A KR 20197027793 A KR20197027793 A KR 20197027793A KR 20190135000 A KR20190135000 A KR 20190135000A
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seq
aavhu68
raav
acid sequence
vector
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Ceased
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마리아 피. 림베리스
안나 피. 트레티아코바
제임스 엠. 윌슨
마이클 나소
주스트 콜크만
로버트 프리센
치앙 왕
Original Assignee
더 트러스티스 오브 더 유니버시티 오브 펜실바니아
얀센 바이오테크 인코포레이티드
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Publication of KR20190135000A publication Critical patent/KR20190135000A/ko
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
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    • A—HUMAN NECESSITIES
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C12N7/06—Inactivation or attenuation by chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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  • Chemical Kinetics & Catalysis (AREA)
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  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020197027793A 2017-02-28 2018-02-27 Aav 벡터를 기반으로 하는 인플루엔자 백신 Ceased KR20190135000A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762464753P 2017-02-28 2017-02-28
US62/464,753 2017-02-28
US201762504293P 2017-05-10 2017-05-10
US62/504,293 2017-05-10
US201762560834P 2017-09-20 2017-09-20
US62/560,834 2017-09-20
US201862618443P 2018-01-17 2018-01-17
US62/618,443 2018-01-17
PCT/US2018/019974 WO2018160573A1 (en) 2017-02-28 2018-02-27 Influenza vaccines based on aav vectors

Publications (1)

Publication Number Publication Date
KR20190135000A true KR20190135000A (ko) 2019-12-05

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KR1020197027793A Ceased KR20190135000A (ko) 2017-02-28 2018-02-27 Aav 벡터를 기반으로 하는 인플루엔자 백신

Country Status (13)

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US (2) US10786568B2 (https=)
EP (1) EP3589649A1 (https=)
JP (1) JP2020510430A (https=)
KR (1) KR20190135000A (https=)
CN (1) CN110573523A (https=)
AU (1) AU2018229293A1 (https=)
BR (1) BR112019017697A2 (https=)
CA (1) CA3052487A1 (https=)
IL (1) IL268445A (https=)
SG (2) SG11201907611WA (https=)
TW (1) TW201837170A (https=)
UY (1) UY37620A (https=)
WO (1) WO2018160573A1 (https=)

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