KR20190124326A - 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템 - Google Patents

유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템 Download PDF

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KR20190124326A
KR20190124326A KR1020197031339A KR20197031339A KR20190124326A KR 20190124326 A KR20190124326 A KR 20190124326A KR 1020197031339 A KR1020197031339 A KR 1020197031339A KR 20197031339 A KR20197031339 A KR 20197031339A KR 20190124326 A KR20190124326 A KR 20190124326A
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cells
unit
automated system
cell
automated
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Korean (ko)
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스콧 노글
케빈 에간
스티븐 창
수잔 엘. 솔로몬
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뉴욕 스템 셀 파운데이션, 인코포레이티드
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Priority to KR1020217024088A priority Critical patent/KR102439238B1/ko
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts

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  • Sustainable Development (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analytical Chemistry (AREA)
  • Computer Hardware Design (AREA)
KR1020197031339A 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템 Ceased KR20190124326A (ko)

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KR1020217024088A KR102439238B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템

Applications Claiming Priority (7)

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US201161565818P 2011-12-01 2011-12-01
US61/565,818 2011-12-01
US201161580007P 2011-12-23 2011-12-23
US61/580,007 2011-12-23
US201261700792P 2012-09-13 2012-09-13
US61/700,792 2012-09-13
PCT/US2012/067417 WO2013082509A1 (en) 2011-12-01 2012-11-30 Automated system for producing induced pluripotent stem cells or differentiated cells

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KR1020147017723A Division KR102039202B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템

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KR1020197031339A Ceased KR20190124326A (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
KR1020217024088A Active KR102439238B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
KR1020247003083A Ceased KR20240019378A (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
KR1020147017723A Active KR102039202B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
KR1020227029866A Active KR102631374B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템

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KR1020247003083A Ceased KR20240019378A (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
KR1020147017723A Active KR102039202B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
KR1020227029866A Active KR102631374B1 (ko) 2011-12-01 2012-11-30 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템

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EP (2) EP3653698B1 (enExample)
JP (1) JP6257520B2 (enExample)
KR (5) KR20190124326A (enExample)
CN (2) CN110724636A (enExample)
AU (4) AU2012345676B2 (enExample)
BR (2) BR122020005735B1 (enExample)
CA (2) CA2857295C (enExample)
DK (2) DK3653698T3 (enExample)
ES (2) ES3038941T3 (enExample)
IL (3) IL299477B1 (enExample)
IN (1) IN2014CN04920A (enExample)
WO (1) WO2013082509A1 (enExample)
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CA2857295C (en) 2021-06-29
IL232869B (en) 2022-02-01
KR102039202B1 (ko) 2019-10-31
CA3118842C (en) 2023-12-12
AU2021212081B2 (en) 2024-02-29
US20130345094A1 (en) 2013-12-26
IL299477B1 (en) 2026-05-01
IL232869A0 (en) 2014-07-31
ZA202205833B (en) 2024-09-25
US10273459B2 (en) 2019-04-30
CN104080906A (zh) 2014-10-01
ES2773863T3 (es) 2020-07-15
KR102439238B1 (ko) 2022-08-31
US20210332330A1 (en) 2021-10-28
JP2015502747A (ja) 2015-01-29
ZA201403945B (en) 2018-08-29
EP2785829A1 (en) 2014-10-08
DK3653698T3 (da) 2025-07-07
BR122020005735B1 (pt) 2021-12-28
AU2018286561A1 (en) 2019-01-24
EP3653698B1 (en) 2025-04-02
US20190352613A1 (en) 2019-11-21
EP2785829A4 (en) 2015-04-29
ZA201803502B (en) 2022-12-21
KR20240019378A (ko) 2024-02-14
CA2857295A1 (en) 2013-06-06
AU2012345676B2 (en) 2018-10-04
CN110724636A (zh) 2020-01-24
US11732242B2 (en) 2023-08-22
DK2785829T3 (da) 2020-01-27
KR20140101393A (ko) 2014-08-19
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AU2012345676A1 (en) 2014-06-19
IL289822A (en) 2022-03-01
US10968435B2 (en) 2021-04-06
AU2021212081A1 (en) 2021-08-26
CA3118842A1 (en) 2013-06-06
IL289822B2 (en) 2023-06-01
KR102631374B1 (ko) 2024-01-29
BR112014013152A2 (pt) 2017-06-13
ES3038941T3 (en) 2025-10-16
KR20210096700A (ko) 2021-08-05
US20240191203A1 (en) 2024-06-13
AU2024203546A1 (en) 2024-06-20
EP3653698A1 (en) 2020-05-20
KR20220141823A (ko) 2022-10-20
IN2014CN04920A (enExample) 2015-09-18
BR112014013152B1 (pt) 2021-08-31
JP6257520B2 (ja) 2018-01-10
WO2013082509A1 (en) 2013-06-06
IL299477A (en) 2023-02-01

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