CN110724636A - 用于产生诱导多能干细胞或分化细胞的自动化系统 - Google Patents

用于产生诱导多能干细胞或分化细胞的自动化系统 Download PDF

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Publication number
CN110724636A
CN110724636A CN201911063727.3A CN201911063727A CN110724636A CN 110724636 A CN110724636 A CN 110724636A CN 201911063727 A CN201911063727 A CN 201911063727A CN 110724636 A CN110724636 A CN 110724636A
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cells
cell
ipscs
automated
differentiated
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Chinese (zh)
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S·诺格
K·艾甘
S·常
S·L·所罗门
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New York Stem Cell Foundation Inc
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
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  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analytical Chemistry (AREA)
  • Computer Hardware Design (AREA)
CN201911063727.3A 2011-12-01 2012-11-30 用于产生诱导多能干细胞或分化细胞的自动化系统 Pending CN110724636A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161565818P 2011-12-01 2011-12-01
US61/565,818 2011-12-01
US201161580007P 2011-12-23 2011-12-23
US61/580,007 2011-12-23
US201261700792P 2012-09-13 2012-09-13
US61/700,792 2012-09-13
CN201280068799.7A CN104080906A (zh) 2011-12-01 2012-11-30 用于产生诱导多能干细胞或分化细胞的自动化系统

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CN110724636A true CN110724636A (zh) 2020-01-24

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CN201280068799.7A Pending CN104080906A (zh) 2011-12-01 2012-11-30 用于产生诱导多能干细胞或分化细胞的自动化系统

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US (4) US10273459B2 (enExample)
EP (2) EP3653698B1 (enExample)
JP (1) JP6257520B2 (enExample)
KR (5) KR20190124326A (enExample)
CN (2) CN110724636A (enExample)
AU (4) AU2012345676B2 (enExample)
BR (2) BR122020005735B1 (enExample)
CA (2) CA2857295C (enExample)
DK (2) DK3653698T3 (enExample)
ES (2) ES3038941T3 (enExample)
IL (3) IL299477B1 (enExample)
IN (1) IN2014CN04920A (enExample)
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Cited By (1)

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TWI822127B (zh) * 2021-06-17 2023-11-11 美商建南德克公司 改良式模擬神經病症之培養系統及方法

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CN109923204A (zh) * 2016-07-21 2019-06-21 塞尔艾德 用于细胞的自动化独立并行批量处理的方法和装置
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WO2018155607A1 (ja) * 2017-02-24 2018-08-30 剛士 田邊 細胞処理装置、浮遊培養器、及び幹細胞の誘導方法
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WO2019068022A1 (en) * 2017-09-30 2019-04-04 Inscripta, Inc. CONTINUOUS FLOW ELECTROPORATION INSTRUMENTATION
JPWO2019240008A1 (ja) * 2018-06-13 2021-06-24 富士フイルム株式会社 情報処理装置、導出方法、及び導出プログラム
JP6530577B1 (ja) * 2019-03-20 2019-06-12 剛士 田邊 細胞処理システム及び細胞処理装置
JP7090337B2 (ja) * 2019-03-20 2022-06-24 アイ ピース，インコーポレイテッド 細胞処理システム及び細胞処理装置
JP6530874B1 (ja) * 2019-03-20 2019-06-12 剛士 田邊 細胞処理システム及び細胞処理装置
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CN114606198A (zh) * 2022-03-25 2022-06-10 深圳临研医学有限公司 成骨发育不全诱导多能干细胞及其构建方法
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CA2857295C (en) 2021-06-29
IL232869B (en) 2022-02-01
KR102039202B1 (ko) 2019-10-31
CA3118842C (en) 2023-12-12
AU2021212081B2 (en) 2024-02-29
US20130345094A1 (en) 2013-12-26
IL299477B1 (en) 2026-05-01
IL232869A0 (en) 2014-07-31
ZA202205833B (en) 2024-09-25
US10273459B2 (en) 2019-04-30
CN104080906A (zh) 2014-10-01
ES2773863T3 (es) 2020-07-15
KR102439238B1 (ko) 2022-08-31
US20210332330A1 (en) 2021-10-28
JP2015502747A (ja) 2015-01-29
ZA201403945B (en) 2018-08-29
EP2785829A1 (en) 2014-10-08
DK3653698T3 (da) 2025-07-07
BR122020005735B1 (pt) 2021-12-28
AU2018286561A1 (en) 2019-01-24
EP3653698B1 (en) 2025-04-02
US20190352613A1 (en) 2019-11-21
EP2785829A4 (en) 2015-04-29
ZA201803502B (en) 2022-12-21
KR20240019378A (ko) 2024-02-14
CA2857295A1 (en) 2013-06-06
AU2012345676B2 (en) 2018-10-04
US11732242B2 (en) 2023-08-22
DK2785829T3 (da) 2020-01-27
KR20140101393A (ko) 2014-08-19
EP2785829B1 (en) 2019-10-16
AU2012345676A1 (en) 2014-06-19
IL289822A (en) 2022-03-01
US10968435B2 (en) 2021-04-06
AU2021212081A1 (en) 2021-08-26
CA3118842A1 (en) 2013-06-06
IL289822B2 (en) 2023-06-01
KR102631374B1 (ko) 2024-01-29
BR112014013152A2 (pt) 2017-06-13
ES3038941T3 (en) 2025-10-16
KR20210096700A (ko) 2021-08-05
US20240191203A1 (en) 2024-06-13
AU2024203546A1 (en) 2024-06-20
EP3653698A1 (en) 2020-05-20
KR20220141823A (ko) 2022-10-20
IN2014CN04920A (enExample) 2015-09-18
BR112014013152B1 (pt) 2021-08-31
JP6257520B2 (ja) 2018-01-10
WO2013082509A1 (en) 2013-06-06
KR20190124326A (ko) 2019-11-04
IL299477A (en) 2023-02-01

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