KR20190122664A - 헌팅턴 병 치료를 위한 PPARγ효현제 - Google Patents

헌팅턴 병 치료를 위한 PPARγ효현제 Download PDF

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Publication number
KR20190122664A
KR20190122664A KR1020197023202A KR20197023202A KR20190122664A KR 20190122664 A KR20190122664 A KR 20190122664A KR 1020197023202 A KR1020197023202 A KR 1020197023202A KR 20197023202 A KR20197023202 A KR 20197023202A KR 20190122664 A KR20190122664 A KR 20190122664A
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KR
South Korea
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subject
disease
huntington
therapeutically effective
effective amount
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KR1020197023202A
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English (en)
Korean (ko)
Inventor
바바라 핀크
로렌스 스타인만
Original Assignee
코히러스 바이오사이언시스, 인크.
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Publication of KR20190122664A publication Critical patent/KR20190122664A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197023202A 2017-01-18 2018-01-18 헌팅턴 병 치료를 위한 PPARγ효현제 Ceased KR20190122664A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762447741P 2017-01-18 2017-01-18
US62/447,741 2017-01-18
PCT/US2018/014240 WO2018136635A1 (en) 2017-01-18 2018-01-18 Pparϒ agonist for the treatment of huntington's disease

Publications (1)

Publication Number Publication Date
KR20190122664A true KR20190122664A (ko) 2019-10-30

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ID=62908392

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197023202A Ceased KR20190122664A (ko) 2017-01-18 2018-01-18 헌팅턴 병 치료를 위한 PPARγ효현제

Country Status (13)

Country Link
US (1) US20190350918A1 (https=)
EP (1) EP3570841A4 (https=)
JP (1) JP2020505448A (https=)
KR (1) KR20190122664A (https=)
CN (1) CN110461330A (https=)
AU (1) AU2018210165A1 (https=)
BR (1) BR112019014529A2 (https=)
CA (1) CA3050104A1 (https=)
EA (1) EA201991716A1 (https=)
IL (1) IL268008A (https=)
MX (1) MX2019008535A (https=)
SG (1) SG11201906644YA (https=)
WO (1) WO2018136635A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201791982A1 (ru) 2015-03-09 2020-02-17 Интекрин Терапьютикс, Инк. Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8895541B2 (en) * 2002-09-04 2014-11-25 James A. Carnazza Methods for inhibiting the development of huntington's disease
US20040224995A1 (en) * 2003-05-09 2004-11-11 University Of North Texas Health Science Center At Fort Worth Neuroprotective effects of PPARy agonists against cellular oxidative insults
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
DE10351744A1 (de) * 2003-10-31 2005-06-16 Schering Ag Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
JP2008515978A (ja) * 2004-10-13 2008-05-15 ユニバーシティ オブ コネチカット カンナビネルジック脂質リガンド
WO2009097996A1 (de) * 2008-02-07 2009-08-13 Sanofi-Aventis Verwendung von substituierten phenylimidazolidinen zur herstellung von arzneimitteln zur behandlung des metabolischen syndroms
WO2010040055A2 (en) * 2008-10-03 2010-04-08 Intekrin Therapeutics, Inc. Oral pharmaceutical formulations for antidiabetic compounds
EP2448412B1 (en) * 2009-07-01 2019-05-01 JDS Therapeutics, LLC Chromium complexes as enhancers of brain glucose transporters
TW201609098A (zh) * 2013-12-20 2016-03-16 泰瓦藥品工業有限公司 拉喹莫德(laquinimod)於延緩亨丁頓舞蹈症進展的用途

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Publication number Publication date
IL268008A (en) 2019-09-26
CA3050104A1 (en) 2018-07-26
BR112019014529A2 (pt) 2020-02-27
EA201991716A1 (ru) 2020-02-04
EP3570841A4 (en) 2020-08-19
MX2019008535A (es) 2019-12-02
EP3570841A1 (en) 2019-11-27
WO2018136635A1 (en) 2018-07-26
JP2020505448A (ja) 2020-02-20
CN110461330A (zh) 2019-11-15
US20190350918A1 (en) 2019-11-21
AU2018210165A1 (en) 2019-08-01
SG11201906644YA (en) 2019-08-27

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