KR20190082192A - 암 치료를 위한 다수의 사이토카인 성분 함유 생물제제와 pd-1/pd-l1 저해제 및/또는 ctla-4 저해제의 사용 - Google Patents

암 치료를 위한 다수의 사이토카인 성분 함유 생물제제와 pd-1/pd-l1 저해제 및/또는 ctla-4 저해제의 사용 Download PDF

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KR20190082192A
KR20190082192A KR1020197007858A KR20197007858A KR20190082192A KR 20190082192 A KR20190082192 A KR 20190082192A KR 1020197007858 A KR1020197007858 A KR 1020197007858A KR 20197007858 A KR20197007858 A KR 20197007858A KR 20190082192 A KR20190082192 A KR 20190082192A
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biological agent
primary cell
derived biological
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존 더블유. 하덴
네일 엘. 베린스테인
제임스 이. 이건
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브루클린 이뮤노테라퓨틱스 엘엘씨
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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KR1020197007858A 2016-08-19 2017-08-18 암 치료를 위한 다수의 사이토카인 성분 함유 생물제제와 pd-1/pd-l1 저해제 및/또는 ctla-4 저해제의 사용 Ceased KR20190082192A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662377051P 2016-08-19 2016-08-19
US62/377,051 2016-08-19
PCT/US2017/047477 WO2018035395A1 (en) 2016-08-19 2017-08-18 Uses of pd-1/pd-l1 inhibitors and/or ctla-4 inhibitors with a biologic containing multiple cytokine components to treat cancer

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KR20190082192A true KR20190082192A (ko) 2019-07-09

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KR1020197007858A Ceased KR20190082192A (ko) 2016-08-19 2017-08-18 암 치료를 위한 다수의 사이토카인 성분 함유 생물제제와 pd-1/pd-l1 저해제 및/또는 ctla-4 저해제의 사용

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US (1) US20200330557A1 (https=)
EP (1) EP3500290A4 (https=)
JP (2) JP2019524887A (https=)
KR (1) KR20190082192A (https=)
CN (1) CN109890405A (https=)
AU (1) AU2017312121A1 (https=)
BR (1) BR112019003248A2 (https=)
CA (1) CA3034266A1 (https=)
EA (1) EA201990530A1 (https=)
MX (1) MX2019002023A (https=)
PH (1) PH12019550027A1 (https=)
SG (1) SG11201901271VA (https=)
WO (1) WO2018035395A1 (https=)
ZA (1) ZA201901258B (https=)

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WO2021071127A1 (ko) * 2019-10-11 2021-04-15 경북대학교 산학협력단 엑소좀 pd-l1의 발현에 대한 억제제를 유효성분으로 포함하는 항암 효과 증진용 조성물

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SG10201609131YA (en) 2016-11-01 2018-06-28 Xylonix Ip Holdings Pte Ltd Zinc-pga compositions and methods for treating cancer
BR112019018915A2 (pt) 2017-03-15 2020-04-14 Pandion Therapeutics Inc imunotolerância direcionada
JP2020521452A (ja) 2017-05-24 2020-07-27 パンディオン・セラピューティクス・インコーポレイテッド 標的化免疫寛容
AU2018326633A1 (en) * 2017-08-30 2020-03-26 Sanford Burnham Prebys Medical Discovery Institute TP53 as biomarker for responsiveness to immunotherapy
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
USRE50550E1 (en) 2017-12-06 2025-08-26 Pandion Operations, Inc. IL-2 muteins and uses thereof
AU2019290345B2 (en) * 2018-06-22 2025-07-10 Xylonix PTE. LTD. Oncology treatments using zinc agents
WO2020236875A1 (en) 2019-05-20 2020-11-26 Pandion Therapeutics, Inc. Madcam targeted immunotolerance
CN110746493A (zh) * 2019-09-06 2020-02-04 中国药科大学 一种pd-l1拮抗剂多肽及其应用
AU2019479828B2 (en) * 2019-12-27 2024-01-18 Wuhan Vast Conduct Science Foundation Co., Ltd. Composition and method for treatment of multiple sclerosis
US11981715B2 (en) 2020-02-21 2024-05-14 Pandion Operations, Inc. Tissue targeted immunotolerance with a CD39 effector
CN113450877B (zh) * 2021-06-28 2022-04-08 深圳裕泰抗原科技有限公司 一种基于多重免疫组化技术的生物标志物分析方法及其应用
JP2025508823A (ja) 2022-02-23 2025-04-10 ブライト ピーク セラピューティクス エージー 免疫抗原特異的ｉｌ－１８免疫サイトカイン及びその使用
WO2024215753A2 (en) * 2023-04-10 2024-10-17 Oregon Health & Science University Combination therapy for treatment of solid tumors

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MX2011012147A (es) * 2009-05-15 2012-06-19 Irx Therapeutics Inc Inmunoterapia de vacuna.
PT2619576T (pt) * 2010-09-24 2020-09-14 Niels Grabe Meios e métodos para a previsão de resposta ao tratamento de um paciente com cancro
MX385194B (es) * 2014-02-21 2025-03-14 Nektar Therapeutics India Pvt Ltd Agonistas il-2rbeta-selectivos en combinación con un anticuerpo anti-ctla-4 o un anticuerpo anti-pd-1.
AU2015327868A1 (en) * 2014-10-03 2017-04-20 Novartis Ag Combination therapies
TWI716362B (zh) * 2014-10-14 2021-01-21 瑞士商諾華公司 針對ｐｄ－ｌ１之抗體分子及其用途

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021071127A1 (ko) * 2019-10-11 2021-04-15 경북대학교 산학협력단 엑소좀 pd-l1의 발현에 대한 억제제를 유효성분으로 포함하는 항암 효과 증진용 조성물

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JP2023116576A (ja) 2023-08-22
EP3500290A4 (en) 2020-04-29
MX2019002023A (es) 2019-11-18
AU2017312121A1 (en) 2019-03-21
CA3034266A1 (en) 2018-02-22
ZA201901258B (en) 2020-11-25
CN109890405A (zh) 2019-06-14
JP2019524887A (ja) 2019-09-05
EP3500290A1 (en) 2019-06-26
BR112019003248A2 (pt) 2019-10-01
PH12019550027A1 (en) 2019-07-24
US20200330557A1 (en) 2020-10-22
EA201990530A1 (ru) 2019-07-31
WO2018035395A1 (en) 2018-02-22
SG11201901271VA (en) 2019-03-28

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