CN109890405A - Pd-1/pd-l1抑制剂和/或ctla-4抑制剂与含有多种细胞因子组分的生物制剂用于治疗癌症的用途 - Google Patents

Pd-1/pd-l1抑制剂和/或ctla-4抑制剂与含有多种细胞因子组分的生物制剂用于治疗癌症的用途 Download PDF

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CN109890405A
CN109890405A CN201780063783.XA CN201780063783A CN109890405A CN 109890405 A CN109890405 A CN 109890405A CN 201780063783 A CN201780063783 A CN 201780063783A CN 109890405 A CN109890405 A CN 109890405A
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antagonist
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biological agent
cancer
cell
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J·W·哈登
N·L·贝琳斯丁
J·E·伊根
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Brooklyn Immunotherapy Co Ltd
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Brooklyn Immunotherapy Co Ltd
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CN201780063783.XA 2016-08-19 2017-08-18 Pd-1/pd-l1抑制剂和/或ctla-4抑制剂与含有多种细胞因子组分的生物制剂用于治疗癌症的用途 Pending CN109890405A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662377051P 2016-08-19 2016-08-19
US62/377,051 2016-08-19
PCT/US2017/047477 WO2018035395A1 (en) 2016-08-19 2017-08-18 Uses of pd-1/pd-l1 inhibitors and/or ctla-4 inhibitors with a biologic containing multiple cytokine components to treat cancer

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US (1) US20200330557A1 (https=)
EP (1) EP3500290A4 (https=)
JP (2) JP2019524887A (https=)
KR (1) KR20190082192A (https=)
CN (1) CN109890405A (https=)
AU (1) AU2017312121A1 (https=)
BR (1) BR112019003248A2 (https=)
CA (1) CA3034266A1 (https=)
EA (1) EA201990530A1 (https=)
MX (1) MX2019002023A (https=)
PH (1) PH12019550027A1 (https=)
SG (1) SG11201901271VA (https=)
WO (1) WO2018035395A1 (https=)
ZA (1) ZA201901258B (https=)

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JP2020521452A (ja) 2017-05-24 2020-07-27 パンディオン・セラピューティクス・インコーポレイテッド 標的化免疫寛容
AU2018326633A1 (en) * 2017-08-30 2020-03-26 Sanford Burnham Prebys Medical Discovery Institute TP53 as biomarker for responsiveness to immunotherapy
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
USRE50550E1 (en) 2017-12-06 2025-08-26 Pandion Operations, Inc. IL-2 muteins and uses thereof
AU2019290345B2 (en) * 2018-06-22 2025-07-10 Xylonix PTE. LTD. Oncology treatments using zinc agents
WO2020236875A1 (en) 2019-05-20 2020-11-26 Pandion Therapeutics, Inc. Madcam targeted immunotolerance
CN110746493A (zh) * 2019-09-06 2020-02-04 中国药科大学 一种pd-l1拮抗剂多肽及其应用
US20240082358A1 (en) * 2019-10-11 2024-03-14 Kyungpook National University Industry-Academic Cooperation Foundation Composition comprising inhibitor against expression of exosomal pd-l1 as active ingredient for enhancing anticancer effect
AU2019479828B2 (en) * 2019-12-27 2024-01-18 Wuhan Vast Conduct Science Foundation Co., Ltd. Composition and method for treatment of multiple sclerosis
US11981715B2 (en) 2020-02-21 2024-05-14 Pandion Operations, Inc. Tissue targeted immunotolerance with a CD39 effector
JP2025508823A (ja) 2022-02-23 2025-04-10 ブライト ピーク セラピューティクス エージー 免疫抗原特異的il-18免疫サイトカイン及びその使用
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CN113450877B (zh) * 2021-06-28 2022-04-08 深圳裕泰抗原科技有限公司 一种基于多重免疫组化技术的生物标志物分析方法及其应用

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MX2019002023A (es) 2019-11-18
AU2017312121A1 (en) 2019-03-21
CA3034266A1 (en) 2018-02-22
ZA201901258B (en) 2020-11-25
JP2019524887A (ja) 2019-09-05
EP3500290A1 (en) 2019-06-26
KR20190082192A (ko) 2019-07-09
BR112019003248A2 (pt) 2019-10-01
PH12019550027A1 (en) 2019-07-24
US20200330557A1 (en) 2020-10-22
EA201990530A1 (ru) 2019-07-31
WO2018035395A1 (en) 2018-02-22
SG11201901271VA (en) 2019-03-28

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