KR20190039754A - Dpp-iv 지속형 저해제의 결정 및 이의 염 - Google Patents
Dpp-iv 지속형 저해제의 결정 및 이의 염 Download PDFInfo
- Publication number
- KR20190039754A KR20190039754A KR1020197006819A KR20197006819A KR20190039754A KR 20190039754 A KR20190039754 A KR 20190039754A KR 1020197006819 A KR1020197006819 A KR 1020197006819A KR 20197006819 A KR20197006819 A KR 20197006819A KR 20190039754 A KR20190039754 A KR 20190039754A
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- KR
- South Korea
- Prior art keywords
- formula
- compound
- compound represented
- crystal
- fumarate
- Prior art date
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- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610665625.9 | 2016-08-12 | ||
| CN201610666564 | 2016-08-12 | ||
| CN201610665625 | 2016-08-12 | ||
| CN201610666564.8 | 2016-08-12 | ||
| PCT/CN2017/097046 WO2018028666A1 (zh) | 2016-08-12 | 2017-08-11 | Dpp-iv长效抑制剂的结晶及其盐 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20190039754A true KR20190039754A (ko) | 2019-04-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197006819A Withdrawn KR20190039754A (ko) | 2016-08-12 | 2017-08-11 | Dpp-iv 지속형 저해제의 결정 및 이의 염 |
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| US (1) | US10822319B2 (enExample) |
| EP (1) | EP3498704A4 (enExample) |
| JP (1) | JP6997760B2 (enExample) |
| KR (1) | KR20190039754A (enExample) |
| CN (1) | CN109874304B (enExample) |
| AU (1) | AU2017308691B2 (enExample) |
| CA (1) | CA3033890A1 (enExample) |
| RU (1) | RU2753335C9 (enExample) |
| WO (1) | WO2018028666A1 (enExample) |
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| CN108456196A (zh) * | 2017-02-22 | 2018-08-28 | 四川科伦博泰生物医药股份有限公司 | 3-氨基四氢吡喃衍生物的盐及其多晶型、其制备方法和用途 |
| CN111793071B (zh) * | 2020-07-06 | 2021-06-04 | 四川凯科医药科技有限公司 | 奥格列汀的合成工艺 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2001041016A2 (en) * | 1999-12-02 | 2001-06-07 | General Electric Company | System and method for valuing loan portfolios using fuzzy clustering |
| CA2640924C (en) * | 2006-02-15 | 2013-10-08 | Merck & Co., Inc. | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
| JO2870B1 (en) * | 2008-11-13 | 2015-03-15 | ميرك شارب اند دوهم كورب | Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes |
| TWI574965B (zh) * | 2011-06-29 | 2017-03-21 | 默沙東藥廠 | 二肽基肽酶－ｉｖ抑制劑之新穎結晶型 |
| US9937153B2 (en) * | 2013-08-30 | 2018-04-10 | Merck Sharp & Dohme Ltd. | Oral pharmaceutical formulation of omarigliptin |
| CN105985357A (zh) * | 2015-02-12 | 2016-10-05 | 北京赛林泰医药技术有限公司 | 取代的氨基六元饱和杂脂环类长效dpp-iv抑制剂 |
| WO2017031918A1 (zh) | 2015-08-24 | 2017-03-02 | 四川科伦药物研究院有限公司 | 长效二肽基肽酶-iv抑制剂、用途及其中间体的制备方法 |
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2017
- 2017-08-11 AU AU2017308691A patent/AU2017308691B2/en not_active Expired - Fee Related
- 2017-08-11 EP EP17838796.5A patent/EP3498704A4/en not_active Withdrawn
- 2017-08-11 RU RU2019105352A patent/RU2753335C9/ru active
- 2017-08-11 JP JP2019506673A patent/JP6997760B2/ja not_active Expired - Fee Related
- 2017-08-11 US US16/324,884 patent/US10822319B2/en active Active
- 2017-08-11 WO PCT/CN2017/097046 patent/WO2018028666A1/zh not_active Ceased
- 2017-08-11 CN CN201780044045.0A patent/CN109874304B/zh active Active
- 2017-08-11 CA CA3033890A patent/CA3033890A1/en not_active Abandoned
- 2017-08-11 KR KR1020197006819A patent/KR20190039754A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| RU2019105352A3 (enExample) | 2020-12-17 |
| EP3498704A4 (en) | 2020-03-04 |
| RU2753335C9 (ru) | 2021-09-20 |
| CA3033890A1 (en) | 2018-02-15 |
| US10822319B2 (en) | 2020-11-03 |
| WO2018028666A1 (zh) | 2018-02-15 |
| AU2017308691A1 (en) | 2019-03-28 |
| US20190284153A1 (en) | 2019-09-19 |
| EP3498704A1 (en) | 2019-06-19 |
| JP6997760B2 (ja) | 2022-01-18 |
| RU2019105352A (ru) | 2020-09-14 |
| AU2017308691B2 (en) | 2021-12-16 |
| JP2019527708A (ja) | 2019-10-03 |
| CN109874304B (zh) | 2021-06-25 |
| RU2753335C2 (ru) | 2021-08-13 |
| CN109874304A (zh) | 2019-06-11 |
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