KR20180118198A - 수지상 세포 감염을 위한 멀티모달 벡터(multimodal vector for dendritic cell infection) - Google Patents

수지상 세포 감염을 위한 멀티모달 벡터(multimodal vector for dendritic cell infection) Download PDF

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Publication number
KR20180118198A
KR20180118198A KR1020187028404A KR20187028404A KR20180118198A KR 20180118198 A KR20180118198 A KR 20180118198A KR 1020187028404 A KR1020187028404 A KR 1020187028404A KR 20187028404 A KR20187028404 A KR 20187028404A KR 20180118198 A KR20180118198 A KR 20180118198A
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nucleic acid
recombinant nucleic
acid vector
cancer
virus
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Korean (ko)
Inventor
패트릭 순-시옹
케이반 니아지
샤루즈 라비자데
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난트셀, 인크.
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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1777—Integrin superfamily
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020187028404A 2016-03-18 2017-03-20 수지상 세포 감염을 위한 멀티모달 벡터(multimodal vector for dendritic cell infection) Ceased KR20180118198A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662310551P 2016-03-18 2016-03-18
US62/310,551 2016-03-18
US201662313596P 2016-03-25 2016-03-25
US62/313,596 2016-03-25
PCT/US2017/023117 WO2017161360A2 (en) 2016-03-18 2017-03-20 Multimodal vector for dendritic cell infection

Publications (1)

Publication Number Publication Date
KR20180118198A true KR20180118198A (ko) 2018-10-30

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ID=59850551

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KR1020187028404A Ceased KR20180118198A (ko) 2016-03-18 2017-03-20 수지상 세포 감염을 위한 멀티모달 벡터(multimodal vector for dendritic cell infection)

Country Status (11)

Country Link
US (1) US20210198689A1 (https=)
EP (1) EP3430148A4 (https=)
JP (1) JP2019508044A (https=)
KR (1) KR20180118198A (https=)
CN (1) CN109312364A (https=)
AU (1) AU2017233072B2 (https=)
CA (1) CA3016389A1 (https=)
IL (1) IL261812A (https=)
MX (1) MX2018011306A (https=)
SG (1) SG11201808058PA (https=)
WO (1) WO2017161360A2 (https=)

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HRP20200439T1 (hr) 2015-04-30 2020-06-12 Psioxus Therapeutics Limited Onkolitički adenovirus koji kodira protein b7
AU2016311444B2 (en) 2015-08-25 2019-02-07 Nantomics, Llc Systems and methods for high-accuracy variant calling
BR112018012180A2 (pt) 2015-12-17 2018-12-04 Psioxus Therapeutics Ltd vírus de codificação de um anticorpo ou fragmento de complexo anti-tcr
EP4101447A1 (en) 2016-06-30 2022-12-14 Nant Holdings IP, LLC Nant cancer vaccine
GB201713765D0 (en) 2017-08-28 2017-10-11 Psioxus Therapeutics Ltd Modified adenovirus
IL303187A (en) 2016-08-29 2023-07-01 Akamis Bio Ltd Adenovirus with bispecific T cell activator
DK3630143T5 (da) 2017-06-01 2024-09-02 Akamis Bio Ltd Onkolytisk virus og fremgangsmåde
GB201801614D0 (en) 2018-01-31 2018-03-14 Psioxus Therapeutics Ltd Formulation
US11823773B2 (en) 2018-04-13 2023-11-21 Nant Holdings Ip, Llc Nant cancer vaccine strategies

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EP1385538B1 (en) * 2001-04-05 2013-01-30 The Johns Hopkins University Chimeric Vaccines comprising the lumenal domain of LAMP-1 or LAMP-2
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Publication number Publication date
WO2017161360A2 (en) 2017-09-21
CA3016389A1 (en) 2017-09-21
IL261812A (en) 2018-10-31
CN109312364A (zh) 2019-02-05
AU2017233072B2 (en) 2020-12-24
US20210198689A1 (en) 2021-07-01
JP2019508044A (ja) 2019-03-28
WO2017161360A4 (en) 2017-11-16
WO2017161360A3 (en) 2017-10-26
EP3430148A2 (en) 2019-01-23
AU2017233072A1 (en) 2018-09-13
MX2018011306A (es) 2019-08-16
EP3430148A4 (en) 2020-01-01
SG11201808058PA (en) 2018-10-30

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