KR20170125951A - 화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 - Google Patents
화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 Download PDFInfo
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- KR20170125951A KR20170125951A KR1020177028558A KR20177028558A KR20170125951A KR 20170125951 A KR20170125951 A KR 20170125951A KR 1020177028558 A KR1020177028558 A KR 1020177028558A KR 20177028558 A KR20177028558 A KR 20177028558A KR 20170125951 A KR20170125951 A KR 20170125951A
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- Life Sciences & Earth Sciences (AREA)
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- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP09382144A EP2292236A1 (en) | 2009-08-14 | 2009-08-14 | Sigma ligands for the prevention or treatment of pain induced by chemotherapy |
| EP09382144.5 | 2009-08-14 | ||
| PCT/EP2010/061720 WO2011018487A1 (en) | 2009-08-14 | 2010-08-12 | Sigma ligands for the prevention or treatment of pain induced by chemotherapy |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157034281A Division KR20150140419A (ko) | 2009-08-14 | 2010-08-12 | 화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 |
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| KR20170125951A true KR20170125951A (ko) | 2017-11-15 |
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| KR1020157034281A Ceased KR20150140419A (ko) | 2009-08-14 | 2010-08-12 | 화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 |
| KR1020127006715A Expired - Fee Related KR101605151B1 (ko) | 2009-08-14 | 2010-08-12 | 화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1020157034281A Ceased KR20150140419A (ko) | 2009-08-14 | 2010-08-12 | 화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 |
| KR1020127006715A Expired - Fee Related KR101605151B1 (ko) | 2009-08-14 | 2010-08-12 | 화학요법에 의해 유도되는 통증의 예방 또는 치료를 위한 시그마 리간드 |
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| EP2116539A1 (en) | 2008-04-25 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof |
| EP2353591A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof |
| EP2353598A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for use in the prevention and/or treatment of postoperative pain |
| EP2388005A1 (en) | 2010-05-21 | 2011-11-23 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy |
| EP2415471A1 (en) | 2010-08-03 | 2012-02-08 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in opioid-induced hyperalgesia |
| EP2426111A1 (en) * | 2010-08-09 | 2012-03-07 | Laboratorios Del. Dr. Esteve, S.A. | 4-[-2-[[5-methyl-1-(2-naphtalenyl)-1h-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride amorphous solid forms |
| EP2524694A1 (en) * | 2011-05-19 | 2012-11-21 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in diabetes type-2 associated pain |
| EP2792352A1 (en) | 2013-04-16 | 2014-10-22 | Laboratorios Del. Dr. Esteve, S.A. | Alpha-2 adrenoreceptor and sigma receptor ligand combinations |
| TN2016000084A1 (en) * | 2013-09-12 | 2017-07-05 | Esteve Labor Dr | Nsaid and sigma receptor ligand combinations |
| TW201607539A (zh) | 2013-12-17 | 2016-03-01 | 以斯提夫博士實驗室股份有限公司 | 加巴噴丁類似物和σ受體配體組合物 |
| JP2016540771A (ja) | 2013-12-17 | 2016-12-28 | ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ | セロトニン−ノルアドレナリン再取り込み阻害薬（ｓｎｒｉ）およびシグマ受容体リガンドの組み合わせ |
| TW201808300A (zh) * | 2016-06-06 | 2018-03-16 | 以斯提夫博士實驗室股份有限公司 | σ受體配體在癌症中的用途 |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| WO2024105225A1 (en) * | 2022-11-18 | 2024-05-23 | Universitat De Barcelona | Synergistic combinations of a sigma receptor 1 (s1r) antagonist and a soluble epoxide hydrolase inhibitor (sehi) and their use in the treatment of pain |
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| SU11248A1 (ru) | 1927-03-29 | 1929-09-30 | В.С. Григорьев | Способ очистки антрацена |
| FR2301250A1 (fr) * | 1975-02-21 | 1976-09-17 | Bellon Labor Sa Roger | Nouveaux diaryl-1, 4o-aminoalcoxy-3 pyrazoles et leurs sels |
| US7696199B2 (en) | 2004-08-27 | 2010-04-13 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
| EP1634872A1 (en) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Pyrazole derivatives as sigma receptor inhibitors |
| ES2396421T3 (es) * | 2004-08-27 | 2013-02-21 | Laboratorios Del Dr. Esteve, S.A. | Inhibidores del receptor sigma |
| US8202872B2 (en) * | 2006-03-01 | 2012-06-19 | Laboratorios Del Dr. Esteve, S.A. | Pyrazole derivatives as sigma receptor inhibitors |
| CN101395157A (zh) * | 2006-03-01 | 2009-03-25 | 伊斯特芬博士实验室有限公司 | 作为西格玛受体抑制剂的吡唑衍生物 |
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