KR20170097045A - 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물 - Google Patents

알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물 Download PDF

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KR20170097045A
KR20170097045A KR1020177016896A KR20177016896A KR20170097045A KR 20170097045 A KR20170097045 A KR 20170097045A KR 1020177016896 A KR1020177016896 A KR 1020177016896A KR 20177016896 A KR20177016896 A KR 20177016896A KR 20170097045 A KR20170097045 A KR 20170097045A
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South Korea
Prior art keywords
desmopressin
alpha
adrenergic receptor
administered
receptor antagonist
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Ceased
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KR1020177016896A
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English (en)
Korean (ko)
Inventor
시모어 에이치. 페인
린다 쳉
마리아 쳉
사무엘 헤르쉬코비츠
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알레간 인코포레이티드
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Priority to KR1020247000547A priority Critical patent/KR20240010751A/ko
Publication of KR20170097045A publication Critical patent/KR20170097045A/ko
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    • A61K38/11—
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A61K31/75—Polymers of hydrocarbons of ethene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
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    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020177016896A 2014-11-20 2015-11-19 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물 Ceased KR20170097045A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247000547A KR20240010751A (ko) 2014-11-20 2015-11-19 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462082301P 2014-11-20 2014-11-20
US62/082,301 2014-11-20
PCT/US2015/061686 WO2016081772A1 (en) 2014-11-20 2015-11-19 Methods and compositions comprising desmopressin in combination with an alpha-adrenergic receptor antagonist

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KR1020247000547A Division KR20240010751A (ko) 2014-11-20 2015-11-19 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물

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KR20170097045A true KR20170097045A (ko) 2017-08-25

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KR1020177016896A Ceased KR20170097045A (ko) 2014-11-20 2015-11-19 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물
KR1020247000547A Ceased KR20240010751A (ko) 2014-11-20 2015-11-19 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물

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US (1) US10286033B2 (enExample)
EP (1) EP3220942B1 (enExample)
JP (4) JP2017535567A (enExample)
KR (2) KR20170097045A (enExample)
CN (1) CN106999538A (enExample)
AU (1) AU2015349811B2 (enExample)
CA (1) CA2967390A1 (enExample)
DK (1) DK3220942T3 (enExample)
ES (1) ES2923438T3 (enExample)
MX (1) MX2017006655A (enExample)
WO (1) WO2016081772A1 (enExample)

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EP4687859A2 (en) 2023-04-04 2026-02-11 Tulex Pharmaceuticals, Inc. Desmopressin oral compositions

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JP2017535567A (ja) 2017-11-30
JP2020097632A (ja) 2020-06-25
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US20170319646A1 (en) 2017-11-09
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