KR20170095965A - 간 및 위장 질환의 치료에 사용하기 위한 fxr 효능제로서의 아자비시클로옥탄 유도체 - Google Patents
간 및 위장 질환의 치료에 사용하기 위한 fxr 효능제로서의 아자비시클로옥탄 유도체 Download PDFInfo
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- KR20170095965A KR20170095965A KR1020177019415A KR20177019415A KR20170095965A KR 20170095965 A KR20170095965 A KR 20170095965A KR 1020177019415 A KR1020177019415 A KR 1020177019415A KR 20177019415 A KR20177019415 A KR 20177019415A KR 20170095965 A KR20170095965 A KR 20170095965A
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- azabicyclo
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| EP3919489A4 (en) * | 2019-01-31 | 2022-10-12 | The National Institutes of Pharmaceutical R&D Co., Ltd | AROMATIC RING OR HETEROAROMATIC RING COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND MEDICAL USE |
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| JP7599014B2 (ja) * | 2020-06-30 | 2024-12-12 | オクヴィルク，ゼレン | グアニル酸シクラーゼｃ（ｇｕｃｙ２ｃ）アゴニストおよび短鎖脂肪酸またはそのプロドラッグの組み合わせを含む医薬組成物 |
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| CN113292555B (zh) * | 2021-04-28 | 2022-03-18 | 武汉纽瑞斯医药科技有限公司 | 一种Tropifexor的制备方法 |
| CN116987062A (zh) * | 2023-08-03 | 2023-11-03 | 中国热带农业科学院分析测试中心 | 一种氨基酸键联槟榔碱衍生物的制备方法 |
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| JP2009511450A (ja) * | 2005-10-07 | 2009-03-19 | ノバルティス アクチエンゲゼルシャフト | ニロチニブとファルネシルトランスフェラーゼ阻害剤の組合せ |
| WO2012087520A1 (en) * | 2010-12-20 | 2012-06-28 | Irm Llc | Compositions and methods for modulating farnesoid x receptors |
| CU24152B1 (es) * | 2010-12-20 | 2016-02-29 | Irm Llc | 1,2 oxazol-8-azabiciclo[3,2,1]octano 8 il como moduladores de fxr |
| EP2545964A1 (en) * | 2011-07-13 | 2013-01-16 | Phenex Pharmaceuticals AG | Novel FXR (NR1H4) binding and activity modulating compounds |
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| WO2016097933A1 (en) | 2016-06-23 |
| RU2017125365A3 (enExample) | 2019-07-17 |
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| US20190083473A1 (en) | 2019-03-21 |
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| TW201628615A (zh) | 2016-08-16 |
| JP2017537960A (ja) | 2017-12-21 |
| CN107106555A (zh) | 2017-08-29 |
| IL252596A0 (en) | 2017-07-31 |
| US20170368038A1 (en) | 2017-12-28 |
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| MX2017008057A (es) | 2017-09-28 |
| CA2970866A1 (en) | 2016-06-23 |
| PH12017501046A1 (en) | 2017-11-27 |
| AU2015365481B2 (en) | 2018-08-09 |
| CL2017001566A1 (es) | 2018-03-23 |
| BR112017011972A2 (pt) | 2017-12-26 |
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