KR20170086057A - Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도 - Google Patents

Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도 Download PDF

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KR20170086057A
KR20170086057A KR1020177015188A KR20177015188A KR20170086057A KR 20170086057 A KR20170086057 A KR 20170086057A KR 1020177015188 A KR1020177015188 A KR 1020177015188A KR 20177015188 A KR20177015188 A KR 20177015188A KR 20170086057 A KR20170086057 A KR 20170086057A
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mmol
methyl
compound
pyrazole
ring
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Korean (ko)
Inventor
캐서린 조랑드-르브룅
레이날도 존스
애니 초 원
응안 응우엔
테레사 엘. 존슨
리즈베스 셀레스트 드셀름
코식 판다
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메르크 파텐트 게엠베하
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Priority to KR1020237038922A priority Critical patent/KR102683518B1/ko
Publication of KR20170086057A publication Critical patent/KR20170086057A/ko
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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KR1020177015188A 2014-11-20 2015-11-19 Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도 Ceased KR20170086057A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237038922A KR102683518B1 (ko) 2014-11-20 2015-11-19 Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462082231P 2014-11-20 2014-11-20
US62/082,231 2014-11-20
PCT/US2015/061463 WO2016081679A1 (en) 2014-11-20 2015-11-19 Heteroaryl compounds as irak inhibitors and uses thereof

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KR1020237038922A Division KR102683518B1 (ko) 2014-11-20 2015-11-19 Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도

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KR20170086057A true KR20170086057A (ko) 2017-07-25

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KR1020237038922A Active KR102683518B1 (ko) 2014-11-20 2015-11-19 Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도
KR1020177015188A Ceased KR20170086057A (ko) 2014-11-20 2015-11-19 Irak 억제제로서 헤테로아릴 화합물 및 이들의 용도

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US (2) US9790221B2 (OSRAM)
EP (1) EP3221306B1 (OSRAM)
JP (1) JP6787892B2 (OSRAM)
KR (2) KR102683518B1 (OSRAM)
CN (1) CN107108561B (OSRAM)
AR (1) AR103138A1 (OSRAM)
AU (1) AU2015349899B9 (OSRAM)
CA (1) CA2964982C (OSRAM)
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