KR20170015504A - 소분자 유출 펌프 억제제 - Google Patents

소분자 유출 펌프 억제제 Download PDF

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KR20170015504A
KR20170015504A KR1020177000672A KR20177000672A KR20170015504A KR 20170015504 A KR20170015504 A KR 20170015504A KR 1020177000672 A KR1020177000672 A KR 1020177000672A KR 20177000672 A KR20177000672 A KR 20177000672A KR 20170015504 A KR20170015504 A KR 20170015504A
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substituted
unsubstituted
formula
heteroaryl
efflux pump
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Korean (ko)
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폴 엠 던맨
캐틀린 이 블란차드
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유니버시티 오브 로체스터
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    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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WO2018183382A1 (en) 2017-03-27 2018-10-04 The Regents Of The University Of Colorado, A Body Corporate Small molecule inhibitors of bacterial efflux pumps and methods of using same
CN107216305B (zh) * 2017-05-03 2020-05-08 中国人民解放军第四军医大学 一类苯并吡喃类化合物及其应用
EP3737664B8 (en) * 2018-01-09 2024-07-17 The Hong Kong Polytechnic University Antimicrobial 2-[[(phenyl)imino]methyl]-4-nitro-phenol derivatives and related compounds as inhibitors of the nusb-nuse interaction of microorganisms for the treatment of bacterial infections
JP7062792B2 (ja) 2018-02-13 2022-05-06 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
EP3781556B1 (en) 2018-04-19 2025-06-18 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
CN118221646A (zh) 2018-07-13 2024-06-21 吉利德科学公司 Pd-1/pd-l1抑制剂
TWI811428B (zh) 2018-08-21 2023-08-11 日商杏林製藥股份有限公司 雙環雜芳香環衍生物
CN108822089A (zh) * 2018-08-22 2018-11-16 大连理工大学 2-芳基咪唑烷类化合物、制备方法及其作为Hsp90抑制剂在抗肿瘤上的应用
KR102635333B1 (ko) 2018-10-24 2024-02-15 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors

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