KR20160143017A - cosmetis composition having peptide - Google Patents

Abstract

The present invention provides a cosmetic composition for improving wrinkles and promoting cell regeneration, which comprises 18 to 22% by weight of a peptide and 28 to 32% by weight of a natural-derived functional A composition comprising 18 to 22% by weight of jojoba oil, 6 to 10% by weight of apricot seed oil, 14 to 18% by weight of base, 1.5 to 2.5% by weight squalane, 1.5 to 2.5% by weight of hyaluronic acid And a peptide containing 1.5 to 2.5% by weight of vitamin K or a vitamin K derivative as an active ingredient.

Description

The present invention relates to a cosmetic composition having a peptide as an active ingredient,

The present invention relates to a cosmetic composition comprising a peptide as an active ingredient, and more particularly to a cosmetic composition comprising a peptide having an improved wrinkle and cell regeneration ability to prevent aging of the skin as an active ingredient.

Skin composed of epidermis, dermis, and subcutaneous fat is the most important body that constitutes the human body and plays an important role in various roles such as temperature control function, excretion function, respiration function, human body protection function and barrier function. However, as the age increases, the function of the skin suddenly deteriorates, and various changes occur, thereby progressing aging. Particularly, it is known that the active oxygen generated by the increase of ultraviolet rays and air pollution and the excessive fatigue and stress of the modern person acts as a main cause of skin aging by oxidizing or denaturing biological components.

On the other hand, as the physiological changes of the skin due to aging, the thickness of the skin, the dermis, and the subcutaneous tissue, which are constituents of the skin, becomes thinner and the lipid barrier of the skin barrier functions, The moisture content of the skin is lowered and the skin becomes dry and wrinkles occur.

In addition, various forms of aging may occur, such as skin blackening phenomena such as spiny freckles and pigmentation. Here, skin melanogenesis is a defense mechanism against stimuli such as ultraviolet light in a melanocyte-producing cell (melanocyte), and melanin production activity is increased, and a large amount of melanin produced thereby is transferred to keratinocyte, It is the result of accumulation.

Although melanin protects the skin, hyperpigmentation of the skin causes skin irritation, freckles, darkening of the skin after inflammation of the skin, aging of the skin, and so on. .

This process of melanin production is made by a non-enzymatic oxidation reaction after tyrosine tyrosine, which is an amino acid, is converted into DOPA and dopaquinone by an enzyme called tyrosinase, It is said that it is deposited in the skin to cause stain and black spots.

Materials for inhibiting melanin production such as hydroquinone, arbutin, vitamin C and derivatives thereof have been developed and disclosed as whitening cosmetic compositions containing the same in order to alleviate, prevent, and treat pigmentation, stain, have. Here, the hydroquinone is generally recognized for its effectiveness, but its sensitivity is generally limited.

On the other hand, the skin of the human being is exposed to chemical and physical stimuli of the outside, the normal function of the skin is deteriorated and problems are caused, and the aging phenomenon of the skin is promoted and the skin is damaged. It is known that skin wrinkles are generated by the combined action of various factors such as moisture content of skin, collagen content and immunity against external environment. Among these factors, collagenase activity and collagenase activity, which reduce collagen production and collagen content, have the greatest effect on the formation of wrinkles.

 As described above, various compositions have been conventionally disclosed for suppressing skin whitening and wrinkling. For example, various extracts extracted from L-ascorbic acid and its derivatives, hydroquinone, arbutin, licorice, and herbal extracts are used as skin lightening agents and wrinkle removers. However, L-ascorbic acid is easily oxidized to cause irritation to the skin. The cosmetic composition containing the L-ascorbic acid causes discoloration and irregularities, and arubitin is substantially inferior in skin-improving effect.

Korean Patent No. 10-0337113

In order to solve the above problems, a cosmetic composition containing as an active ingredient a peptide having an improved wrinkle and cell regeneration ability to prevent skin aging is provided.

In order to solve the above problems, the present invention provides a cosmetic composition for improving wrinkles and promoting cell regeneration, comprising 18 to 22 wt% of a peptide, 28 to 32 wt% of a functional additive derived from nature, 18 to 22 wt% % Of squalene, 1.5 to 2.5 wt% of hyaluronic acid, 1.5 to 2.5 wt% of hyaluronic acid, 6 to 10 wt% of apricot seed oil, 14 to 18 wt% of base, 1.5 to 2.5 wt% Of a vitamin K or a vitamin K derivative as an active ingredient.

Here, the peptide is preferably composed of at least one selected from the group consisting of powdered tripeptides, oligopeptides, acetylhexapeptides, pentapeptides, and acetylheptape peptides.

Preferably, the functional additive comprises at least one selected from caviar, pineapple, and powders obtained by drying and crushing grapes.

Alternatively, the functional additive may be composed of any one selected from caviar, pineapple, and grape obtained by extracting the skin improving ingredient from the grape, drying and grinding.

On the other hand, the base is preferably composed of any one selected from purified water and glycolic acid.

Through the above-mentioned solution, the cosmetic composition comprising the peptide according to the present invention as an active ingredient provides the following effects.

First, vitamin K, which is included together with peptides that improve skin regeneration power and improve skin elasticity by improving wrinkles caused by aging, promotes cell regeneration of the peptide while reducing blushing and inflammation of the skin, The synergy effect that uniformly improves is provided, and the satisfaction of the user can be remarkably improved.

Second, the functional additives obtained through various kinds of materials such as caviar, pineapple and grape are included in a single or mixed form, and thus, they can be used as nutrition and moisture supply, slimming, skin endotoxin release, whitening, A variety of complex skin improving effects can be provided, and the additives are derived from natural ingredients, so that side effects are minimized and stable.

Hereinafter, a cosmetic composition comprising a peptide according to a preferred embodiment of the present invention as an active ingredient will be described in detail with reference to the accompanying drawings.

In detail, the cosmetic composition comprising the peptide according to the present invention as an active ingredient includes peptides, functional additives derived from nature, jojoba oil, apricot seed oil, base, squalene, hyaluronic acid and vitamin K or vitamin K derivatives. At this time, the components and the composition ratios thereof are shown in Table 1 below.

ingredient Composition ratio (% by weight) Peptide powder 18-22 Functional additive 28 ~ 32 Jojoba oil 18-22 Apricot seed oil 6 to 10 Base 14-18 Squalene 1.5 to 2.5 Hyaluronic acid 1.5 to 2.5 Vitamin K 1.5 to 2.5

As shown in Table 1, the cosmetic composition according to the present invention contains 18 to 22% by weight of the peptide as an active ingredient. The peptide may be at least one selected from the group consisting of powdered tripeptide, oligopeptide, acetyl hexapeptide, pentapeptide and acetylheptapeptide. .

In detail, the peptide is a unit formed by combining a plurality of amino acids, which are basic units of proteins constituting human tissue. Depending on the binding of these amino acids, the peptide that penetrates into the skin and performs various functions can be obtained. For example, the acetylhexapeptide group may affect the repetitive motion of the wrinkles by controlling the signal transmission process of the nerve cells connected to the wrinkle muscles, thereby increasing the elasticity of the skin and providing the effect of improving the wrinkles.

As described above, the peptide contained in the cosmetic composition induces the activation of enzymes acting on the regeneration of the skin tissue while helping to improve wrinkles, thereby improving the biosynthesis rate of molecules constituting other skin such as collagen So that skin regeneration and skin tension of the user can be improved. In addition, the amount of biosynthesis of the collagenase degrading the collagen is reduced to maintain skin elasticity, thereby preventing aging of the skin, thereby significantly improving the satisfaction of the user.

The peptide may be a variety of known peptides in addition to the above-described constituent groups, and a single peptide may be used. However, at least one peptide may be mixed to provide various synergistic effects.

On the other hand, it is preferable that the functional additive derived from nature is mixed in an amount of 28 to 32% by weight. Herein, the functional additive derived from natural origin is preferably composed of at least one selected from powder obtained by drying and crushing caviar, pineapple and grape. The types and effects of the functional additives are shown in Table 2 below.

Functional additive effect Caviar powder Nutrition, hydration Pineapple powder Skin toxin release, slimming effect Grape powder Whitening, Prevention

As shown in Table 2, a cosmetic composition capable of providing various effects according to the functional additive can be provided. In detail, caviar is an egg of sturgeon and is composed of nutrients such as protein, fat, sugar, vitamins and minerals. In addition, the protein contained in the caviar is water-soluble and can be selected from the group consisting of glutamic acid, aspartic acid, leucine, isoleucine, lysine, alanine, serine, arginine and the like are uniformly distributed.

In addition, fat-soluble vitamins A and D, as well as water-soluble vitamins including vitamin B group and vitamin C are well-balanced. The fat is composed of cholesterol and lecithin, and is effective for regeneration of lipid membrane of dermis. In addition, it is possible to prevent skin moisturizing function, cell regeneration function, protecting function of skin and hair, and aging caused by antioxidant action.

The pineapple is a fruit having a sour taste and a sweet taste including sucrose and citric acid, and is rich in vitamins A, B, and C, and includes a protease called bromelain The bromelin inhibits blood clotting by hydrolyzing fibrin and fibrinogen of serum. In addition, the pineapple promotes lipolysis by decomposing triglyceride in adipocytes into free fatty acid and glycerol, thereby providing a slimming effect of the human body using the cosmetic.

In addition, the grape is mainly composed of tannin, anthocyanin, flavonoid, and can provide an antioxidant effect for preventing arteriosclerosis and removing active oxygen. In addition, by inhibiting the activity of tyrosinase, melanin production can be prevented and a whitening effect can be provided. At this time, it is preferable that the grapes use not only the flesh but also the husks and seed parts. That is, since beneficial ingredients such as polyphenol, which is contained in a large amount in the husks and seeds, can be included in the cosmetic composition, the whitening effect that can be provided through the grapes can be further improved.

Preferably, the functional additive comprises at least one selected from caviar, pineapple, and powder obtained by drying and pulverizing the grape. That is, by mixing the cosmetic composition shown in Table 1, the caviar, pineapple, and the functional additive obtained by drying and powdering the grape, the effect of each additive can be provided together. Furthermore, the caviar, the pineapple and the grape powder may be mixed individually, or may be mixed with each other by at least two or more to provide a more complex skin improving effect.

Alternatively, the functional additive may be composed of any one selected from caviar, pineapple, and powders obtained by extracting, drying and grinding the components for skin improvement extracted from grapes. That is, by extracting the dyestuff-improving ingredient required from the caviar, pineapple and the grapes, the ingredients that may be irritating to the skin are minimized, and thus the stability may be improved.

Furthermore, the grape may be improved in economic efficiency and productivity by using the grape powder or the functional ingredient powder extracted from the grape as a natural material that can be easily obtained.

That is, the cosmetic composition includes single or mixed functional additives obtained through various kinds of materials such as caviar, pineapple and grape. This can provide a variety of complex skin enhancement effects, such as nutrition and hydration, slimming, toxin release, whitening, and anti-stain, depending on the nature of each additive. In addition, since the functional additive is derived from natural origin, side effects are minimized and stable.

On the other hand, the cosmetic composition preferably contains 18 to 22% by weight of jojoba oil. In detail, the jojoba oil is not oxidized by the higher unsaturated alcohols obtained from seeds of johoba (simmondsia chimensis) and the liquid wax of unsaturated fatty acids, and is rich in natural proteins, minerals and collagen components. In addition, it is similar to the sebaceous structure of the human body, although it is a plant, it has a high affinity for skin, prevents skin dryness and coloring aging, excellently moisturizes and promotes cell regeneration. And because it dissolves fat, it is beneficial for the ground, acne and troublesome skin, and has a slimming effect, so it is a base oil suitable for use in the management of obesity.

In addition, the above-mentioned jojoba oil, which is light and permeable, is very useful for skin troubles and has a high stability against weakness of trouble, long-term storage, water absorption and moisturizing ability, oily acne and atopy. In addition, it strengthens the natural resistance of the skin to cope with bacterial attack, so it can be used for seborrheic skin. Moreover, the jojoba oil contains a complex of minerals and vitamins, which softens the skin as if it is silk and provides a UV-blocking effect.

On the other hand, the cosmetic composition preferably contains 18 to 22% by weight of apricot seed oil. In detail, the apricot seed oil is one of the natural substances containing a large amount of 11 essential amino acids and various minerals which are good for health and skin, and it can remove aging dead skin to keep the skin clean and mitigate stain do. It also has excellent moisture retention and contains vitamins A and B, which can provide vitality to the skin.

On the other hand, the cosmetic composition preferably contains 1.5 to 2.5% by weight of squalene and 1.5 to 2.5% by weight of hyaluronic acid. In detail, the squalene is used as a pharmaceutical and cosmetic preparation in a natural or hydrogenated form as a hydrocarbon-based oil present in a large amount in liver oil such as shark. Here, the squalene may be contained in the cosmetic composition as a skin softening agent and an oil moisturizing agent, and may be provided with an anti-aging effect and skin regeneration effect through an antioxidative effect.

The hyaluronic acid is a colorless, highly viscous polysaccharide having a molecular weight of 500,000 to 13,000,000 Da. The repeating units, glucutonic acid and N-acetyl glucosamine, ) And (1-4), respectively. Such hyaluronic acid has a moisturizing effect, and the moisturizing power increases as the concentration of the hyaluronic acid is higher. In addition, hyaluronic acid has excellent lubrication effect on physical friction and is used in cosmetics in various kinds.

Meanwhile, the cosmetic composition preferably contains vitamin K or vitamin K derivative in an amount of 1.5 to 2.5% by weight. Herein, the vitamin K plays an important role in the growth and development of the human body. Especially, it is an important factor of blood coagulation and accumulates in the fat tissue of the body as fat soluble vitamin which is involved in prevention of bleeding. These vitamin K can be absorbed into the skin, and the veins distributed below the skin can be crowded to reduce redness or redness of the skin. In addition, the effect of rapidly healing the bruise and reducing inflammation can also be provided.

Moreover, the vitamin K can be used as an accelerator for promoting the skin regenerating ability of the peptide. That is, the cosmetic composition includes vitamin K, which is included together with a peptide that improves skin regeneration power and improves wrinkles caused by aging and improves skin elasticity, promotes cell regeneration of the peptide, Thereby providing a synergistic effect of brightening and uniformly improving the skin tone, and the satisfaction of the user can be remarkably improved.

At this time, the cosmetic composition may contain the vitamin K derivative in place of the vitamin K. In detail, since the vitamin K derivative is prepared so as to have improved stability than the pure vitamin K, sensitivity to the skin is minimized and the vitamin K derivative can be used stably.

Table 3 below shows the degree of skin improvement according to the content of vitamin K or vitamin K derivative. The degree of skin improvement described above was classified into four groups of 16 women aged 30 to 50 years, irrespective of the invention, and the skin condition measured before use of the cosmetic composition and the composition ratio of the vitamin K Of the cosmetics after one week of use.

At this time, the skin condition is a value obtained by measuring wrinkle improvement degree and skin tone improvement degree. Specifically, the degree of wrinkle improvement was calculated by visually checking the number and depth of the wrinkles changed per predetermined skin area of the eyes or mouth, and the number of wrinkles was reduced to a value between 1 and 5, Understanding is desirable. The degree of improvement of the skin tone is calculated from a score of 1 to 5 by visually confirming the changed skin tone per unit area of the predetermined skin of the ball, and it is preferable that the closer to 5 the greater the improvement of the skin tone.

Vitamin K or vitamin K derivative content
(weight%) A B C D 0 0.1 to 1.4 1.5 to 2.5 2.6+ Degree of skin improvement
Wrinkle improvement 1.8 2.8 4.7 4.6 Improvement of skin tone 1.2 3.4 4.8 4.8
(Skin irritation) 0 (Low improvement) <-----------------------> 5 (High improvement)

As shown in Table 3, when the vitamin or vitamin K derivative is not contained or (A) the content is 1.4% by weight or less (B), it can be confirmed that the effect of improving the skin wrinkles and improving the skin tone is insufficient. When the content of the vitamin K or vitamin K derivative is 2.6% by weight or more (D), the content of the vitamin K or vitamin K derivative is between 1.5 and 2.5% by weight and the effect of improving wrinkles and skin tone is similar, .

Furthermore, even if they are mixed at a high weight%, the difference in degree of improvement of the skin is insufficient, so that the economical efficiency may be lowered. Therefore, it is preferable that the vitamin K or the vitamin K derivative is mixed in an amount of 1.5 to 2.5% by weight.

On the other hand, the cosmetic composition preferably contains 14 to 18% by weight of a base. Here, the base may be any one selected from the group consisting of purified water and glycoric acid. Specifically, the glycolic acid is a fruit acid which can be extracted from sugarcane or fruit, and is a kind of alpha hydroxy acids (AHA's). These glyconic acids give moisture to dry skin and provide the effect of ameliorating other abnormal skin abnormalities including acne, psoriasis and the like. In addition, the keratinous keratinous tissue layer of the outer skin layer may be removed to promote the regenerating ability to regenerate the new skin layer.

The purified water can be used as the base for mixing the cosmetic composition with the glycolic acid as a known purified water. Of course, it is also possible to use a sap of plant water such as purified water or bamboo sap, or to use lactic acid or the like in addition to the glycolic acid. Such modifications are within the scope of the present invention.

In addition, the base may be modified to selectively form the cosmetic composition into a formulation selected from the group consisting of softened longevity, nutritional lotion, nutritional cream, massage cream, essence and pack.

As described above, the present invention is not limited to the above-described embodiments, and variations and modifications may be made by those skilled in the art without departing from the scope of the present invention. And such modifications are within the scope of the present invention.

Claims (5)

A cosmetic composition for improving wrinkles and promoting cell regeneration,
From 18 to 22% by weight of peptides, from 28 to 32% by weight of natural derived functional additives, from 18 to 22% by weight of jojoba oil, from 6 to 10% by weight of apricot seed oil, from 14 to 18% 1. A cosmetic composition comprising, as an active ingredient, a peptide comprising 1.5 to 2.5% by weight of squalene, 1.5 to 2.5% by weight of hyaluronic acid, and 1.5 to 2.5% by weight of vitamin K or a vitamin K derivative. The method according to claim 1,
Wherein the peptide is composed of at least one selected from the group consisting of powdered tripeptides, oligopeptides, acetylhexapeptides, pentapeptides, and acetylheptape peptides. The method according to claim 1,
Wherein the functional additive comprises at least one selected from caviar, pineapple, and powder obtained by drying and crushing grapes. The method according to claim 1,
Wherein the functional additive is selected from the group consisting of powder obtained by extracting the skin improving ingredient from caviar, pineapple and grape, drying and grinding. The method according to claim 1,
Wherein the base comprises any one selected from the group consisting of purified water and glycolic acid.