KR20160091350A - 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신 - Google Patents

중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신

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Publication number
KR20160091350A
KR20160091350A KR1020167015308A KR20167015308A KR20160091350A KR 20160091350 A KR20160091350 A KR 20160091350A KR 1020167015308 A KR1020167015308 A KR 1020167015308A KR 20167015308 A KR20167015308 A KR 20167015308A KR 20160091350 A KR20160091350 A KR 20160091350A
Authority
KR
South Korea
Prior art keywords
mers
acid sequence
seq
spike
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020167015308A
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English (en)
Korean (ko)
Inventor
데이비드 비. 웨이너
카루피아 무투마니
니란잔 와이. 사르데자이
Original Assignee
더 트러스티스 오브 더 유니버시티 오브 펜실바니아
이노비오 파마수티컬즈, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 트러스티스 오브 더 유니버시티 오브 펜실바니아, 이노비오 파마수티컬즈, 인크. filed Critical 더 트러스티스 오브 더 유니버시티 오브 펜실바니아
Priority to KR1020237027157A priority Critical patent/KR20230122181A/ko
Publication of KR20160091350A publication Critical patent/KR20160091350A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020167015308A 2013-11-29 2014-11-26 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신 Ceased KR20160091350A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237027157A KR20230122181A (ko) 2013-11-29 2014-11-26 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361910153P 2013-11-29 2013-11-29
US61/910,153 2013-11-29
PCT/US2014/067537 WO2015081155A1 (en) 2013-11-29 2014-11-26 Mers-cov vaccine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020237027157A Division KR20230122181A (ko) 2013-11-29 2014-11-26 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신

Publications (1)

Publication Number Publication Date
KR20160091350A true KR20160091350A (ko) 2016-08-02

Family

ID=53199622

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020167015308A Ceased KR20160091350A (ko) 2013-11-29 2014-11-26 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신
KR1020237027157A Ceased KR20230122181A (ko) 2013-11-29 2014-11-26 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020237027157A Ceased KR20230122181A (ko) 2013-11-29 2014-11-26 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신

Country Status (10)

Country Link
US (5) US10016497B2 (OSRAM)
EP (1) EP3074051A4 (OSRAM)
JP (1) JP6412131B2 (OSRAM)
KR (2) KR20160091350A (OSRAM)
CN (2) CN112057613A (OSRAM)
AU (1) AU2014354797C1 (OSRAM)
CA (1) CA2932055A1 (OSRAM)
IL (3) IL276210B2 (OSRAM)
SA (1) SA516371223B1 (OSRAM)
WO (1) WO2015081155A1 (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019078600A1 (ko) * 2017-10-19 2019-04-25 (주)에이티젠 중동호흡기증후군 코로나바이러스에 대한 항체 및 이를 이용한 항체역가 측정방법
KR20210136998A (ko) * 2020-05-08 2021-11-17 한림대학교 산학협력단 코로나 바이러스 억제용 펩타이드 및 그 용도

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US10016497B2 (en) * 2013-11-29 2018-07-10 The Trustees Of The Universtiy Of Pennsylvania MERS-CoV vaccine
US11103575B2 (en) 2014-02-28 2021-08-31 The New York Blood Center, Inc. Immunogenic composition for MERS coronavirus infection
EP3045181B1 (en) * 2015-01-19 2018-11-14 Ludwig-Maximilians-Universität München A novel vaccine against the middle east respiratory syndrome coronavirus (MERS-CoV)
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CN106397549B (zh) * 2016-10-11 2019-08-06 中国疾病预防控制中心病毒病预防控制所 MERS-CoV特异性多肽及其应用
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KR20180058206A (ko) * 2016-11-23 2018-05-31 에스케이케미칼 주식회사 중동호흡기증후군 코로나바이러스 s 단백질 면역원 조성물 및 이의 제작 방법
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US11738025B2 (en) 2020-02-04 2023-08-29 Oyagen, Inc. Method for treating coronavirus infections
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CN111378785A (zh) * 2020-03-12 2020-07-07 仁宽(上海)生物科技有限公司 用于核酸诊断新型冠状病毒2019-nCov的假病毒标准品及其应用
US11559577B2 (en) 2020-03-31 2023-01-24 Engimata, Inc. Immunogenic composition forming a vaccine, and a method for its manufacture
WO2021231560A1 (en) * 2020-05-12 2021-11-18 Greffex, Inc. Engineering coronavirus spike proteins as vaccine antigens, their design and uses
US20230210981A1 (en) * 2020-06-09 2023-07-06 The Wistar Institute Of Anatomy And Biology Coronavirus disease 2019 (covid-19) combination vaccine
WO2022011332A2 (en) * 2020-07-10 2022-01-13 Engimata, Inc Immunogenic composition forming a vaccine, and a method for its manufacture
WO2022020604A1 (en) * 2020-07-22 2022-01-27 Greffex, Inc. Multivalent beta-coronavirus vaccines, their design and uses
US20230279361A1 (en) * 2020-07-27 2023-09-07 National University Corporation Shiga University Of Medical Science Method for in vitro proliferating virus belonging to family coronaviridae, method for producing neutralizing antibody to virus belonging to family coronaviridae, and method for producing infection model of severe acute respiratory syndrome coronavirus 2
EP4196158A1 (en) * 2020-08-14 2023-06-21 Julius-Maximilians-Universität Würzburg Salmonella vaccine for the treatment of coronavirus
WO2022046737A1 (en) * 2020-08-25 2022-03-03 The Wistar Institute Of Anatomy And Biology Intradermal mers-cov vaccine
WO2022051816A1 (en) * 2020-09-10 2022-03-17 The Council Of The Queensland Institute Of Medical Research Methods of determining immune response
AU2021340715A1 (en) * 2020-09-11 2023-04-27 Mark J. Cantwell Enhancing immunity using chimeric cd40 ligand and coronavirus vaccine
WO2022236301A1 (en) * 2021-05-05 2022-11-10 Inovio Pharmaceuticals Inc. Vaccines against coronavirus and methods of use

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019078600A1 (ko) * 2017-10-19 2019-04-25 (주)에이티젠 중동호흡기증후군 코로나바이러스에 대한 항체 및 이를 이용한 항체역가 측정방법
KR20210136998A (ko) * 2020-05-08 2021-11-17 한림대학교 산학협력단 코로나 바이러스 억제용 펩타이드 및 그 용도

Also Published As

Publication number Publication date
AU2014354797C1 (en) 2018-02-01
US10548971B2 (en) 2020-02-04
EP3074051A1 (en) 2016-10-05
IL245903B (en) 2020-08-31
AU2014354797B2 (en) 2017-10-26
US20210401972A1 (en) 2021-12-30
WO2015081155A1 (en) 2015-06-04
US20190022213A1 (en) 2019-01-24
US20240123056A1 (en) 2024-04-18
IL305392A (en) 2023-10-01
IL245903A0 (en) 2016-07-31
US11801298B2 (en) 2023-10-31
SA516371223B1 (ar) 2023-01-31
IL276210B1 (en) 2023-09-01
CA2932055A1 (en) 2015-06-04
EP3074051A4 (en) 2017-04-12
IL276210A (en) 2020-09-30
US11135284B2 (en) 2021-10-05
JP2016539946A (ja) 2016-12-22
CN105939730B (zh) 2020-09-11
US20200222527A1 (en) 2020-07-16
AU2014354797A1 (en) 2016-07-07
KR20230122181A (ko) 2023-08-22
JP6412131B2 (ja) 2018-10-24
IL276210B2 (en) 2024-01-01
US10016497B2 (en) 2018-07-10
CN105939730A (zh) 2016-09-14
US20170258893A1 (en) 2017-09-14
CN112057613A (zh) 2020-12-11

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Patent event date: 20240311

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