KR20160020543A - 씨. 디피실에 대해서 면역화시키는 조성물 및 방법 - Google Patents
씨. 디피실에 대해서 면역화시키는 조성물 및 방법 Download PDFInfo
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- KR20160020543A KR20160020543A KR1020167001130A KR20167001130A KR20160020543A KR 20160020543 A KR20160020543 A KR 20160020543A KR 1020167001130 A KR1020167001130 A KR 1020167001130A KR 20167001130 A KR20167001130 A KR 20167001130A KR 20160020543 A KR20160020543 A KR 20160020543A
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- 230000000069 prophylactic effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000032537 response to toxin Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- 201000002516 toxic megacolon Diseases 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US201361835246P | 2013-06-14 | 2013-06-14 | |
| US61/835,246 | 2013-06-14 | ||
| PCT/US2014/042298 WO2014201346A1 (en) | 2013-06-14 | 2014-06-13 | Compositions and methods of immunizing against c. difficile |
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| KR20160020543A true KR20160020543A (ko) | 2016-02-23 |
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| SI3505531T1 (sl) | 2011-04-22 | 2024-02-29 | Wyeth Llc | Kompozicije, povezane z mutantnim toksinom clostridium difficile in njegovimii metodami |
| BR122016023101B1 (pt) | 2012-10-21 | 2022-03-22 | Pfizer Inc | Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile |
| MX2015017257A (es) | 2013-06-14 | 2016-11-11 | Sanofi Pasteur Inc | Composiciones y metodos de inmunizar contra clostridium difficile. |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| AU2018343217B2 (en) * | 2017-09-28 | 2024-11-07 | Pfizer Inc. | Compositions and methods for eliciting an immune response against Clostridium difficile |
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| US5071759A (en) | 1986-05-30 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Army | Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B |
| US6969520B2 (en) * | 1997-10-20 | 2005-11-29 | Acambis Inc. | Active immunization against clostridium difficile disease |
| US6214341B1 (en) | 1997-10-20 | 2001-04-10 | Oravax | Passive immunization against Clostridium difficile disease |
| BRPI0816790A8 (pt) * | 2007-09-14 | 2017-05-16 | Sanofi Pasteur Biologics Co | Composições farmacêuticas contendo toxóides a e b de clostridium difficile |
| GB0921288D0 (en) | 2009-12-04 | 2010-01-20 | Health Prot Agency | Therapies for preventing or suppressing clostridium difficile infection |
| SI3505531T1 (sl) | 2011-04-22 | 2024-02-29 | Wyeth Llc | Kompozicije, povezane z mutantnim toksinom clostridium difficile in njegovimii metodami |
| AR089797A1 (es) | 2012-01-27 | 2014-09-17 | Merck Sharp & Dohme | Vacunas contra clostridum difficile que comprenden toxinas recombinantes |
| GB201206070D0 (en) | 2012-04-04 | 2012-05-16 | Health Prot Agency | Clostridium difficile antigens |
| JP2016516721A (ja) * | 2013-03-15 | 2016-06-09 | サノフィ パストゥール インコーポレイテッド | トキソイド、組成物および関連方法 |
| CN105308066A (zh) * | 2013-03-15 | 2016-02-03 | 圣诺菲·帕斯图尔公司 | 类毒素、组合物和相关的方法 |
| MX2015017257A (es) | 2013-06-14 | 2016-11-11 | Sanofi Pasteur Inc | Composiciones y metodos de inmunizar contra clostridium difficile. |
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2014
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- 2014-06-13 SG SG11201510166YA patent/SG11201510166YA/en unknown
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- 2014-06-13 CN CN201480044768.7A patent/CN105611942A/zh active Pending
- 2014-06-13 EP EP14737429.2A patent/EP3007724B1/en active Active
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2017
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2019
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2021
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Also Published As
| Publication number | Publication date |
|---|---|
| US20210145956A1 (en) | 2021-05-20 |
| US11419930B2 (en) | 2022-08-23 |
| EP3007724A1 (en) | 2016-04-20 |
| AU2014277981A1 (en) | 2016-01-07 |
| CA2915279A1 (en) | 2014-12-18 |
| TWI648063B (zh) | 2019-01-21 |
| CN105611942A (zh) | 2016-05-25 |
| TW201536314A (zh) | 2015-10-01 |
| US20160120968A1 (en) | 2016-05-05 |
| AU2014277981B2 (en) | 2019-06-20 |
| US20200113991A1 (en) | 2020-04-16 |
| JP2016521754A (ja) | 2016-07-25 |
| EP3007724B1 (en) | 2023-07-05 |
| WO2014201346A1 (en) | 2014-12-18 |
| BR112015031088A2 (pt) | 2017-07-25 |
| JP6691477B2 (ja) | 2020-04-28 |
| US20170304423A1 (en) | 2017-10-26 |
| US9730994B2 (en) | 2017-08-15 |
| SG11201510166YA (en) | 2016-01-28 |
| MX2015017257A (es) | 2016-11-11 |
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