MX2015017257A - Composiciones y metodos de inmunizar contra clostridium difficile. - Google Patents
Composiciones y metodos de inmunizar contra clostridium difficile.Info
- Publication number
- MX2015017257A MX2015017257A MX2015017257A MX2015017257A MX2015017257A MX 2015017257 A MX2015017257 A MX 2015017257A MX 2015017257 A MX2015017257 A MX 2015017257A MX 2015017257 A MX2015017257 A MX 2015017257A MX 2015017257 A MX2015017257 A MX 2015017257A
- Authority
- MX
- Mexico
- Prior art keywords
- difficile
- toxin
- methods
- compositions
- subject
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Abstract
Esta descripción se refiere a métodos para provocar una respuesta inmunitaria a la toxina de C. difficile A y la toxina B en un sujeto humano adulto. El sujeto puede estar en riesgo de una infección sintomática de C difficile primaria. En algunas realizaciones, un método es para provocar una respuesta inmunitaria contra la toxina C. difficile A y la toxina B en un sujeto humano adulto en riesgo de una infección sintomática de C. difficile primaria, y comprende administrar al sujeto una composición que comprende C. difficile toxoide a y B toxoide al menos tres veces, siendo cada administración alrededor de siente día de diferencia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361835246P | 2013-06-14 | 2013-06-14 | |
PCT/US2014/042298 WO2014201346A1 (en) | 2013-06-14 | 2014-06-13 | Compositions and methods of immunizing against c. difficile |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015017257A true MX2015017257A (es) | 2016-11-11 |
Family
ID=51168412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015017257A MX2015017257A (es) | 2013-06-14 | 2014-06-13 | Composiciones y metodos de inmunizar contra clostridium difficile. |
Country Status (12)
Country | Link |
---|---|
US (4) | US9730994B2 (es) |
EP (1) | EP3007724B1 (es) |
JP (1) | JP6691477B2 (es) |
KR (1) | KR20160020543A (es) |
CN (1) | CN105611942A (es) |
AU (1) | AU2014277981B2 (es) |
BR (1) | BR112015031088A2 (es) |
CA (1) | CA2915279A1 (es) |
MX (1) | MX2015017257A (es) |
SG (1) | SG11201510166YA (es) |
TW (1) | TWI648063B (es) |
WO (1) | WO2014201346A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2754446C2 (ru) | 2011-04-22 | 2021-09-02 | ВАЙЕТ ЭлЭлСи | Композиции, относящиеся к мутантному токсину CLOSTRIDIUM DIFFICILE, и способы их применения |
BR122016023101B1 (pt) | 2012-10-21 | 2022-03-22 | Pfizer Inc | Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile |
SG11201510166YA (en) | 2013-06-14 | 2016-01-28 | Sanofi Pasteur Inc | Compositions and methods of immunizing against c. difficile |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
KR102625114B1 (ko) * | 2017-09-28 | 2024-01-12 | 화이자 인코포레이티드 | 클로스트리디움 디피실레에 대항한 면역 반응을 도출하기 위한 조성물 및 방법 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5071759A (en) | 1986-05-30 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Army | Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B |
US6969520B2 (en) * | 1997-10-20 | 2005-11-29 | Acambis Inc. | Active immunization against clostridium difficile disease |
WO1999020304A1 (en) * | 1997-10-20 | 1999-04-29 | Oravax, Inc. | Passive immunization against clostridium difficile disease |
HUE037932T2 (hu) * | 2007-09-14 | 2018-09-28 | Sanofi Pasteur Biologics Llc | Clostridium difficile A és B toxoidjait tartalmazó gyógyászati kompozíciók |
GB0921288D0 (en) | 2009-12-04 | 2010-01-20 | Health Prot Agency | Therapies for preventing or suppressing clostridium difficile infection |
RU2754446C2 (ru) | 2011-04-22 | 2021-09-02 | ВАЙЕТ ЭлЭлСи | Композиции, относящиеся к мутантному токсину CLOSTRIDIUM DIFFICILE, и способы их применения |
AR089797A1 (es) | 2012-01-27 | 2014-09-17 | Merck Sharp & Dohme | Vacunas contra clostridum difficile que comprenden toxinas recombinantes |
GB201206070D0 (en) | 2012-04-04 | 2012-05-16 | Health Prot Agency | Clostridium difficile antigens |
JP2016516721A (ja) | 2013-03-15 | 2016-06-09 | サノフィ パストゥール インコーポレイテッド | トキソイド、組成物および関連方法 |
BR112015023469A8 (pt) | 2013-03-15 | 2019-12-03 | Sanofi Pasteur Inc | toxóides, composições e métodos relacionados |
SG11201510166YA (en) | 2013-06-14 | 2016-01-28 | Sanofi Pasteur Inc | Compositions and methods of immunizing against c. difficile |
-
2014
- 2014-06-13 SG SG11201510166YA patent/SG11201510166YA/en unknown
- 2014-06-13 WO PCT/US2014/042298 patent/WO2014201346A1/en active Application Filing
- 2014-06-13 BR BR112015031088A patent/BR112015031088A2/pt not_active Application Discontinuation
- 2014-06-13 KR KR1020167001130A patent/KR20160020543A/ko not_active Application Discontinuation
- 2014-06-13 MX MX2015017257A patent/MX2015017257A/es unknown
- 2014-06-13 EP EP14737429.2A patent/EP3007724B1/en active Active
- 2014-06-13 CA CA2915279A patent/CA2915279A1/en not_active Abandoned
- 2014-06-13 JP JP2016519675A patent/JP6691477B2/ja active Active
- 2014-06-13 CN CN201480044768.7A patent/CN105611942A/zh active Pending
- 2014-06-13 US US14/897,870 patent/US9730994B2/en active Active
- 2014-06-13 AU AU2014277981A patent/AU2014277981B2/en not_active Ceased
- 2014-06-16 TW TW103120772A patent/TWI648063B/zh not_active IP Right Cessation
-
2017
- 2017-07-10 US US15/645,057 patent/US20170304423A1/en not_active Abandoned
-
2019
- 2019-10-21 US US16/658,278 patent/US20200113991A1/en not_active Abandoned
-
2021
- 2021-01-08 US US17/144,486 patent/US11419930B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US9730994B2 (en) | 2017-08-15 |
BR112015031088A2 (pt) | 2017-07-25 |
JP6691477B2 (ja) | 2020-04-28 |
EP3007724B1 (en) | 2023-07-05 |
WO2014201346A1 (en) | 2014-12-18 |
EP3007724A1 (en) | 2016-04-20 |
CA2915279A1 (en) | 2014-12-18 |
US11419930B2 (en) | 2022-08-23 |
JP2016521754A (ja) | 2016-07-25 |
TWI648063B (zh) | 2019-01-21 |
KR20160020543A (ko) | 2016-02-23 |
CN105611942A (zh) | 2016-05-25 |
TW201536314A (zh) | 2015-10-01 |
AU2014277981A1 (en) | 2016-01-07 |
US20200113991A1 (en) | 2020-04-16 |
AU2014277981B2 (en) | 2019-06-20 |
SG11201510166YA (en) | 2016-01-28 |
US20210145956A1 (en) | 2021-05-20 |
US20170304423A1 (en) | 2017-10-26 |
US20160120968A1 (en) | 2016-05-05 |
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