CA2915279A1 - Compositions and methods of immunizing against c. difficile - Google Patents
Compositions and methods of immunizing against c. difficile Download PDFInfo
- Publication number
- CA2915279A1 CA2915279A1 CA2915279A CA2915279A CA2915279A1 CA 2915279 A1 CA2915279 A1 CA 2915279A1 CA 2915279 A CA2915279 A CA 2915279A CA 2915279 A CA2915279 A CA 2915279A CA 2915279 A1 CA2915279 A1 CA 2915279A1
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- administration
- days
- toxin
- difficile
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A61K39/08—Clostridium, e.g. Clostridium tetani
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
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| US201361835246P | 2013-06-14 | 2013-06-14 | |
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| PCT/US2014/042298 WO2014201346A1 (en) | 2013-06-14 | 2014-06-13 | Compositions and methods of immunizing against c. difficile |
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| ES2969952T3 (es) | 2011-04-22 | 2024-05-23 | Wyeth Llc | Composiciones relacionadas con una toxina mutante de Clostridium difficile y sus procedimientos |
| BR122016023101B1 (pt) | 2012-10-21 | 2022-03-22 | Pfizer Inc | Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile |
| CN105611942A (zh) | 2013-06-14 | 2016-05-25 | 圣诺菲·帕斯图尔公司 | 针对艰难梭菌免疫的组合物和方法 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| WO2019064115A1 (en) * | 2017-09-28 | 2019-04-04 | Pfizer Inc. | COMPOSITIONS AND METHODS FOR GENERATING A DIFFICULT CLOSTRIDIUM IMMUNE RESPONSE |
| WO2021255690A2 (en) | 2020-06-19 | 2021-12-23 | Pfizer Inc. | Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof |
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| US5071759A (en) | 1986-05-30 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Army | Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B |
| US6969520B2 (en) | 1997-10-20 | 2005-11-29 | Acambis Inc. | Active immunization against clostridium difficile disease |
| EP1024826B1 (en) | 1997-10-20 | 2005-03-16 | Acambis, Inc. | Passive immunization against clostridium difficile disease |
| EP2198007B1 (en) * | 2007-09-14 | 2017-10-25 | Sanofi Pasteur Biologics, LLC | Pharmaceutical compositions containing clostridium difficile toxoids a and b |
| GB0921288D0 (en) | 2009-12-04 | 2010-01-20 | Health Prot Agency | Therapies for preventing or suppressing clostridium difficile infection |
| ES2969952T3 (es) | 2011-04-22 | 2024-05-23 | Wyeth Llc | Composiciones relacionadas con una toxina mutante de Clostridium difficile y sus procedimientos |
| AR089797A1 (es) | 2012-01-27 | 2014-09-17 | Merck Sharp & Dohme | Vacunas contra clostridum difficile que comprenden toxinas recombinantes |
| GB201206070D0 (en) | 2012-04-04 | 2012-05-16 | Health Prot Agency | Clostridium difficile antigens |
| JP2016516721A (ja) | 2013-03-15 | 2016-06-09 | サノフィ パストゥール インコーポレイテッド | トキソイド、組成物および関連方法 |
| US20160030542A1 (en) | 2013-03-15 | 2016-02-04 | Sanofi Pasteur, Inc. | Toxoid, Compositions and Related Methods |
| CN105611942A (zh) | 2013-06-14 | 2016-05-25 | 圣诺菲·帕斯图尔公司 | 针对艰难梭菌免疫的组合物和方法 |
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Also Published As
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|---|---|
| US20200113991A1 (en) | 2020-04-16 |
| WO2014201346A1 (en) | 2014-12-18 |
| BR112015031088A2 (pt) | 2017-07-25 |
| MX2015017257A (es) | 2016-11-11 |
| TWI648063B (zh) | 2019-01-21 |
| CN105611942A (zh) | 2016-05-25 |
| US20210145956A1 (en) | 2021-05-20 |
| US11419930B2 (en) | 2022-08-23 |
| AU2014277981A1 (en) | 2016-01-07 |
| US20160120968A1 (en) | 2016-05-05 |
| US9730994B2 (en) | 2017-08-15 |
| EP3007724B1 (en) | 2023-07-05 |
| EP3007724A1 (en) | 2016-04-20 |
| AU2014277981B2 (en) | 2019-06-20 |
| SG11201510166YA (en) | 2016-01-28 |
| KR20160020543A (ko) | 2016-02-23 |
| JP2016521754A (ja) | 2016-07-25 |
| TW201536314A (zh) | 2015-10-01 |
| JP6691477B2 (ja) | 2020-04-28 |
| US20170304423A1 (en) | 2017-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190613 |
|
| FZDE | Discontinued |
Effective date: 20210831 |