KR20150143672A - Ras/raf/mek/erk 및 pi3k/akt/pten/mtor 경로의 이중 억제제로서의 퀴나졸린 및 아자퀴나졸린 - Google Patents

Ras/raf/mek/erk 및 pi3k/akt/pten/mtor 경로의 이중 억제제로서의 퀴나졸린 및 아자퀴나졸린 Download PDF

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KR20150143672A
KR20150143672A KR1020157032374A KR20157032374A KR20150143672A KR 20150143672 A KR20150143672 A KR 20150143672A KR 1020157032374 A KR1020157032374 A KR 1020157032374A KR 20157032374 A KR20157032374 A KR 20157032374A KR 20150143672 A KR20150143672 A KR 20150143672A
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sulfonamide
fluorophenyl
fluoropropane
phenyl
alkyl
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스콧 케이. 톰슨
로저 에이. 스미스
산지바 레디
타일러 엠. 존
비제이 쿠마르 냐바난디
호사할리 수브라만야
비제이 포틀루리
수닐 쿠마르 파니그라히
프라브하카라 라오 나디팔리
사우미트라 센굽타
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아사나 바이오사이언시스 엘엘씨
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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KR1020157032374A 2013-04-12 2014-04-11 Ras/raf/mek/erk 및 pi3k/akt/pten/mtor 경로의 이중 억제제로서의 퀴나졸린 및 아자퀴나졸린 Abandoned KR20150143672A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361811408P 2013-04-12 2013-04-12
US61/811,408 2013-04-12
PCT/US2014/033727 WO2014169167A1 (en) 2013-04-12 2014-04-11 Quinazolines and azaquinazolines as dual inhibitors of ras/raf/mek/erk and pi3k/akt/pten/mtor pathways

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KR20150143672A true KR20150143672A (ko) 2015-12-23

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US (5) US9499495B2 (enExample)
EP (1) EP2984088B1 (enExample)
JP (1) JP6496301B2 (enExample)
KR (1) KR20150143672A (enExample)
CN (1) CN105283454B (enExample)
AU (1) AU2014250836C1 (enExample)
BR (1) BR112015025901A8 (enExample)
CA (1) CA2909310A1 (enExample)
IL (2) IL242020B (enExample)
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RU (1) RU2015148359A (enExample)
WO (1) WO2014169167A1 (enExample)
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CN112341434B (zh) * 2019-08-08 2021-11-26 恩瑞生物医药科技（上海）有限公司 PI3K/mTOR蛋白降解靶向嵌合体类化合物及其制备方法和医药用途
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CN113416181B (zh) * 2021-08-02 2022-05-03 四川大学 喹唑啉类衍生物及其用途
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BR112015025901A8 (pt) 2020-01-14
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US9757382B2 (en) 2017-09-12
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WO2014169167A1 (en) 2014-10-16
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IL242020B (en) 2019-08-29
US20210113578A1 (en) 2021-04-22
HK1215810A1 (en) 2016-09-15
US10912779B2 (en) 2021-02-09
US20160068496A1 (en) 2016-03-10
CA2909310A1 (en) 2014-10-16
US20170027953A1 (en) 2017-02-02
US9499495B2 (en) 2016-11-22
CN105283454A (zh) 2016-01-27

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